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• W2001079689 abstract "Lighter is a fast, memory-efficient tool for correcting sequencing errors. Lighter avoids counting k-mers. Instead, it uses a pair of Bloom filters, one holding a sample of the input k-mers and the other holding k-mers likely to be correct. As long as the sampling fraction is adjusted in inverse proportion to the depth of sequencing, Bloom filter size can be held constant while maintaining near-constant accuracy. Lighter is parallelized, uses no secondary storage, and is both faster and more memory-efficient than competing approaches while achieving comparable accuracy." @default.
• W2001079689 created "2016-06-24" @default.
• W2001079689 creator A5009556658 @default.
• W2001079689 creator A5065946017 @default.
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• W2001079689 date "2014-11-01" @default.
• W2001079689 modified "2023-10-06" @default.
• W2001079689 title "Lighter: fast and memory-efficient sequencing error correction without counting" @default.
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• W2001079689 doi "https://doi.org/10.1186/s13059-014-0509-9" @default.
• W2001079689 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4248469" @default.
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• W2001079689 hasPublicationYear "2014" @default.
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