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• W2001127207 abstract "Abstract A bioassay of the toxicity of 12 test chemicals is described using Klebsiella pneumonia grown at 35°C in a medium containing potassium citrate in which the pH increased steadily as the bacteria continued to grow. The chemicals tested were nine metallic ions, two alcohols, and phenol. The pH of the medium was recorded automatically every 3.6 h for 15 h. The 50% inhibitory concentrations (IC50) of the test chemicals (mg/l) were 0.9 for Hg, 2.9 for Cd, 2.9 for Cr6+, 7.5 for Cu, 19 for Cr3+, 25 for Zn, 50 for CN, 91 for Mn, 1,430 for phenol, 53,300 for ethanol, and 74,200 for methanol. LD50 values for rats given the compounds per os and for mice given them intraperitoneally were correlated with the IC50 values obtained by this method. The method might be used in preliminary screening for toxicity before tests in experimental animals." @default.
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• W2001127207 date "1993-01-01" @default.
• W2001127207 modified "2023-09-27" @default.
• W2001127207 title "Microbial bioassay of acute toxicity by the pH inhibition method and comparison of IC50 (pHI) with LD50 for rats and mice" @default.
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• W2001127207 doi "https://doi.org/10.1016/0922-338x(93)90022-z" @default.
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