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• W2001131331 endingPage "74" @default.
• W2001131331 startingPage "65" @default.
• W2001131331 abstract "The prognosis associated with Stage III melanoma is variable (17–65% 5-year survival) and primarily influenced by the number of lymph nodes involved, the presence of ulceration in a primary lesion, and the tumor burden present in each lymph node. In patients with metastatic (Stage IV) melanoma, the prognosis remains dismal (6–18% 5-year survival) and is influenced primarily by the sites (and extent) of metastatic involvement. Serum lactate dehydrogenase is the only prognostic biomarker useful in metastatic melanoma and it has been incorporated into the 2002 American Joint Committee on Cancer tumor, node, metastasis staging system. In this review, the known prognostic factors in Stage III and IV melanoma are reviewed. Selected investigational therapies and associated biomarkers are also discussed." @default.
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• W2001131331 date "2005-01-01" @default.
• W2001131331 modified "2023-09-27" @default.
• W2001131331 title "Biomarkers in melanoma: Stage III and IV disease" @default.
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• W2001131331 doi "https://doi.org/10.1586/14737159.5.1.65" @default.
• W2001131331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15723593" @default.
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