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• W2001147312 abstract "To investigate the mobility rules and influencing factors in lung tumors in order to guide for precisely defining the margin that CTV (clinical target volume) is to be expanded to PTV during stereotactic radiation therapy for lung tumors. A total 83 tumors in 70 cases of patients with primary or metastatic lung cancer were chosen who were subject to robotic radiosurgery including 7 cases of patients with a total of 7 tumors invading the chest wall. Under the guidance by CT, the pure gold mark (tumors) was implanted into or nearby the tumor. With the X-ray simulator system, the range of motion of the gold mark (cancer) was measured. One week later, 16-slice spiral lung CT scan was conducted (1.25 mm thick). According to anatomical borderlines, apex, middle, bottom of the lung were classified. The data on the motion of lung tumors in x (right-left), y (anterior-posterior) and z (superior-inferior) direction was recorded. For 76 lung lesions of 63 patients, the moving distance of apex, middle, and bottom was 1.6 ± 0.8, 2.6 ± 1.1, and 2.8 ± 1.7 mm (F = 1.76, p = 0.179) in x-axis; 2.0 ± 1.3, 4.3 ± 2.8, and 4.0 ± 2.0 mm (F = 2.06, p = 0.135) in y-axis; 2.7 ± 0.8, 7.3 ± 3.6, and 12.0 ± 5.3 mm (F = 16.33, p = 0.000) in z-axis respectively. For 7 lesions invading the chest wall, their moving distance was very small (i.e., 0.9 ± 0.7, 0.7 ± 0.7, and 2.0 ± 0.6 mm, respectively). The correlation analysis showed the moving distance in all directions was related with the patient's sex, age, height, weight and 1s breathing rate (r = −0.001-0.136, p> 0.05). The moving distance due to breathing is mainly affected by the location of the tumor and the status of chest wall involvement. Identification of the mobile rules and the influencing factors is conducive to the internal margin set-up in lung tumor radiation therapy." @default.
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• W2001147312 date "2013-10-01" @default.
• W2001147312 modified "2023-10-16" @default.
• W2001147312 title "Studies on the Mobility Rules of Lung Tumors and the Influencing Factors" @default.
• W2001147312 doi "https://doi.org/10.1016/j.ijrobp.2013.06.1336" @default.
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