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- W2001194223 abstract "Abstract The influences of treatment with drugs, of sex, and of treatment with sex hormones on the liver l -ascorbic acid content in fish were studied. An analysis of various enzymatic steps of the glucuronic acid pathway involved in the synthesis of l -ascorbic acid was made. The data obtained, on most points confirmed the findings in this field obtained with mammals. In mammals the drug-induced increase in the activity of drug-metabolizing enzymes in the liver is accompanied by an increased production of l -ascorbic acid. In fish this drug-metabolizing enzyme inducing activity of drugs is only very slight, while there is a clear response in l -ascorbic acid formation. This makes it doubtful whether there is any direct relationship between the induction of an increased activity of drug-metabolizing enzymes in the liver, and the increased formation of l -ascorbic acid in the liver." @default.
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- W2001194223 date "1968-07-01" @default.
- W2001194223 modified "2023-10-14" @default.
- W2001194223 title "Influence of drugs on liver-ascorbic acid in fish" @default.
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- W2001194223 doi "https://doi.org/10.1016/0006-2952(68)90052-x" @default.
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