Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001196738> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2001196738 endingPage "206" @default.
- W2001196738 startingPage "200" @default.
- W2001196738 abstract "Low bulk concentrations of thyroid stimulating hormone (TSH) were detected by scanning force microscopy (SFM) using gold-labeled conjugates. Anti-TSH antibodies were covalently bound onto amino-modified silicon oxide wafers. Surface modification was examined by contact-angle measurements, ellipsometry, X-ray photoelectron spectroscopy, and SFM. Antibodies were found to form a monolayer of prone molecules with an average surface density of 5000 IgG/μm2. TSH molecules were then allowed to bind to immobilized antibodies. The immunological reaction was quantified by SFM using gold-labeled species. Two scanned force microscopic immunoassays (SFMIA) were compared: first, a competitive test which used gold-labeled TSH molecules mixed with free TSH antigens was performed . Afterward, a sandwich assay was carried out, using gold-labeled anti-TSH antibodies. This latter method was found to be far more sensitive than competitive SFMIA. Gold conjugates were also found to be of great use to quantify antigens in large volumes by a sandwich test: a sensitivity threshold as low as 0.015 ng of TSH/ml (0.075 μUI/ml or 6 × 10−13M) was estimated." @default.
- W2001196738 created "2016-06-24" @default.
- W2001196738 creator A5051202924 @default.
- W2001196738 creator A5068050714 @default.
- W2001196738 creator A5076804187 @default.
- W2001196738 date "1998-02-01" @default.
- W2001196738 modified "2023-09-25" @default.
- W2001196738 title "Thyroid Stimulating Hormone Assays Based on the Detection of Gold Conjugates by Scanning Force Microscopy" @default.
- W2001196738 cites W1984462153 @default.
- W2001196738 cites W1985622275 @default.
- W2001196738 cites W1985900564 @default.
- W2001196738 cites W1990688281 @default.
- W2001196738 cites W2002768661 @default.
- W2001196738 cites W2012464647 @default.
- W2001196738 cites W2038956403 @default.
- W2001196738 cites W2045328900 @default.
- W2001196738 cites W2047397572 @default.
- W2001196738 cites W2049667872 @default.
- W2001196738 cites W2065289349 @default.
- W2001196738 cites W2065324499 @default.
- W2001196738 cites W2067215847 @default.
- W2001196738 cites W2070721943 @default.
- W2001196738 cites W2072306011 @default.
- W2001196738 cites W2079595379 @default.
- W2001196738 cites W2080658437 @default.
- W2001196738 cites W2082460988 @default.
- W2001196738 cites W2092069665 @default.
- W2001196738 cites W4230795423 @default.
- W2001196738 doi "https://doi.org/10.1006/abio.1997.2493" @default.
- W2001196738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9473278" @default.
- W2001196738 hasPublicationYear "1998" @default.
- W2001196738 type Work @default.
- W2001196738 sameAs 2001196738 @default.
- W2001196738 citedByCount "19" @default.
- W2001196738 countsByYear W20011967382014 @default.
- W2001196738 countsByYear W20011967382016 @default.
- W2001196738 countsByYear W20011967382017 @default.
- W2001196738 countsByYear W20011967382019 @default.
- W2001196738 crossrefType "journal-article" @default.
- W2001196738 hasAuthorship W2001196738A5051202924 @default.
- W2001196738 hasAuthorship W2001196738A5068050714 @default.
- W2001196738 hasAuthorship W2001196738A5076804187 @default.
- W2001196738 hasConcept C104819515 @default.
- W2001196738 hasConcept C12554922 @default.
- W2001196738 hasConcept C134306372 @default.
- W2001196738 hasConcept C155672457 @default.
- W2001196738 hasConcept C159654299 @default.
- W2001196738 hasConcept C171250308 @default.
- W2001196738 hasConcept C178790620 @default.
- W2001196738 hasConcept C180577832 @default.
- W2001196738 hasConcept C185592680 @default.
- W2001196738 hasConcept C192562407 @default.
- W2001196738 hasConcept C197336794 @default.
- W2001196738 hasConcept C203014093 @default.
- W2001196738 hasConcept C32909587 @default.
- W2001196738 hasConcept C33923547 @default.
- W2001196738 hasConcept C43617362 @default.
- W2001196738 hasConcept C55493867 @default.
- W2001196738 hasConcept C7070889 @default.
- W2001196738 hasConcept C86803240 @default.
- W2001196738 hasConceptScore W2001196738C104819515 @default.
- W2001196738 hasConceptScore W2001196738C12554922 @default.
- W2001196738 hasConceptScore W2001196738C134306372 @default.
- W2001196738 hasConceptScore W2001196738C155672457 @default.
- W2001196738 hasConceptScore W2001196738C159654299 @default.
- W2001196738 hasConceptScore W2001196738C171250308 @default.
- W2001196738 hasConceptScore W2001196738C178790620 @default.
- W2001196738 hasConceptScore W2001196738C180577832 @default.
- W2001196738 hasConceptScore W2001196738C185592680 @default.
- W2001196738 hasConceptScore W2001196738C192562407 @default.
- W2001196738 hasConceptScore W2001196738C197336794 @default.
- W2001196738 hasConceptScore W2001196738C203014093 @default.
- W2001196738 hasConceptScore W2001196738C32909587 @default.
- W2001196738 hasConceptScore W2001196738C33923547 @default.
- W2001196738 hasConceptScore W2001196738C43617362 @default.
- W2001196738 hasConceptScore W2001196738C55493867 @default.
- W2001196738 hasConceptScore W2001196738C7070889 @default.
- W2001196738 hasConceptScore W2001196738C86803240 @default.
- W2001196738 hasIssue "2" @default.
- W2001196738 hasLocation W20011967381 @default.
- W2001196738 hasLocation W20011967382 @default.
- W2001196738 hasOpenAccess W2001196738 @default.
- W2001196738 hasPrimaryLocation W20011967381 @default.
- W2001196738 hasRelatedWork W1999902982 @default.
- W2001196738 hasRelatedWork W2040541508 @default.
- W2001196738 hasRelatedWork W2063705161 @default.
- W2001196738 hasRelatedWork W2094512380 @default.
- W2001196738 hasRelatedWork W2104799708 @default.
- W2001196738 hasRelatedWork W2346848998 @default.
- W2001196738 hasRelatedWork W2801174013 @default.
- W2001196738 hasRelatedWork W2965618763 @default.
- W2001196738 hasRelatedWork W3012350427 @default.
- W2001196738 hasRelatedWork W3161173879 @default.
- W2001196738 hasVolume "256" @default.
- W2001196738 isParatext "false" @default.
- W2001196738 isRetracted "false" @default.
- W2001196738 magId "2001196738" @default.
- W2001196738 workType "article" @default.