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- W2001197318 abstract "We report experimental imaging results with mice using an array-based photoacoustic tomography system designed for small animal imaging. The system features a 128-element curved transducer array with stage rotation to enable complete two-dimensional tomographic imaging in less than 15 seconds. High fidelity imaging of ex vivo mouse brain vasculature was achieved with resolution of vessels less than 200 microns in diameter in the cortex as well as the cerebellum. Images obtained using varying measurement surface angular spans clearly illustrate the impact on feature definition with orientation. The high sensitivity of the system was demonstrated by images of the brain vasculature with an overlying turbid medium (μa=0.03 cm-1 and μs'~7 cm-1 at 780 nm) of over 2 cm depth. In phantom experiments, high-quality images of blood tubing in a turbid medium were achieved at depths greater than 3 cm for incident fluences of less than 15 mJ/cm2. These results illustrate the suitability for near real-time small animal imaging of deep tissue with high definition.© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only." @default.
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- W2001197318 date "2008-02-07" @default.
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- W2001197318 title "Small animal imaging using a curved array photoacoustic tomography system" @default.
- W2001197318 doi "https://doi.org/10.1117/12.769238" @default.
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