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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001199946> ?p ?o ?g. }

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• W2001199946 abstract "Mitogen-activated protein kinase (MAPK) is an important mediator of cellular signaling pathways. In an attempt to investigate the role of these kinases in contact allergen/irritant-induced signaling cascades, we have utilized keratinocyte (A431 cell line) as antigen presenting cells (APCs). This group has previously reported the applicability of A431 as an APC. The role of these kinases in the elicitation pathways of allergic contact dermatitis was investigated using interleukin-12p40 (IL-12p40) as a marker. Inhibitors of the isoforms of MAPK reduced the allergen-induced IL-12 release in the A431 cell line. This result suggests a possible role of the isoforms of MAPK in the development of contact allergy." @default.
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• W2001199946 date "2007-01-01" @default.
• W2001199946 modified "2023-10-16" @default.
• W2001199946 title "Differential Phosphorylation of MAPK Isoforms in Keratinocyte Cell Line by Contact Allergens and Irritant" @default.
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• W2001199946 doi "https://doi.org/10.1080/15376510600860250" @default.
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