FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001231930> ?p ?o ?g. }

• W2001231930 endingPage "794" @default.
• W2001231930 startingPage "788" @default.
• W2001231930 abstract "Purpose We analyzed variables associated with long-term toxicity using three-dimensional conformal external beam radiation therapy (3D-CRT) to deliver accelerated partial breast irradiation. Methods and Materials One hundred patients treated with 3D-CRT accelerated partial breast irradiation were evaluated using Common Terminology Criteria for Adverse Events version 4.0 scale. Cosmesis was scored using Harvard criteria. Multiple dosimetric and volumetric parameters were analyzed for their association with worst and last (W/L) toxicity outcomes. Results Sixty-two patients had a minimum of 36 months of toxicity follow-up (median follow-up, 4.8 years). The W/L incidence of poor-fair cosmesis, any telangiectasia, and grade ≥2 induration, volume reduction, and pain were 16.4%/11.5%, 24.2%/14.5%, 16.1%/9.7%, 17.7%/12.9%, and 11.3%/3.2%, respectively. Only the incidence of any telangiectasia was found to be predicted by any dosimetric parameter, with the absolute breast volume receiving 5% to 50% of the prescription dose (192.5 cGy–1925 cGy) being significant. No associations with maximum dose, volumes of lumpectomy cavity, breast, modified planning target volume, and PTV, dose homogeneity index, number of fields, and photon energy used were identified with any of the aforementioned toxicities. Non-upper outer quadrant location was associated with grade ≥2 volume reduction (p = 0.02 W/p = 0.04 L). A small cavity-to-skin distance was associated with a grade ≥2 induration (p = 0.03 W/p = 0.01 L), a borderline significant association with grade ≥2 volume reduction (p = 0.06 W/p = 0.06 L) and poor-fair cosmesis (p = 0.08 W/p = 0.09 L), with threshold distances ranging from 5 to 8 mm. Conclusions No dose--volume relationships associated with long-term toxicity were identified in this large patient cohort with extended follow-up. Cosmetic results were good-to-excellent in 88% of patients at 5 years. We analyzed variables associated with long-term toxicity using three-dimensional conformal external beam radiation therapy (3D-CRT) to deliver accelerated partial breast irradiation. One hundred patients treated with 3D-CRT accelerated partial breast irradiation were evaluated using Common Terminology Criteria for Adverse Events version 4.0 scale. Cosmesis was scored using Harvard criteria. Multiple dosimetric and volumetric parameters were analyzed for their association with worst and last (W/L) toxicity outcomes. Sixty-two patients had a minimum of 36 months of toxicity follow-up (median follow-up, 4.8 years). The W/L incidence of poor-fair cosmesis, any telangiectasia, and grade ≥2 induration, volume reduction, and pain were 16.4%/11.5%, 24.2%/14.5%, 16.1%/9.7%, 17.7%/12.9%, and 11.3%/3.2%, respectively. Only the incidence of any telangiectasia was found to be predicted by any dosimetric parameter, with the absolute breast volume receiving 5% to 50% of the prescription dose (192.5 cGy–1925 cGy) being significant. No associations with maximum dose, volumes of lumpectomy cavity, breast, modified planning target volume, and PTV, dose homogeneity index, number of fields, and photon energy used were identified with any of the aforementioned toxicities. Non-upper outer quadrant location was associated with grade ≥2 volume reduction (p = 0.02 W/p = 0.04 L). A small cavity-to-skin distance was associated with a grade ≥2 induration (p = 0.03 W/p = 0.01 L), a borderline significant association with grade ≥2 volume reduction (p = 0.06 W/p = 0.06 L) and poor-fair cosmesis (p = 0.08 W/p = 0.09 L), with threshold distances ranging from 5 to 8 mm. No dose--volume relationships associated with long-term toxicity were identified in this large patient cohort with extended follow-up. Cosmetic results were good-to-excellent in 88% of patients at 5 years." @default.
• W2001231930 created "2016-06-24" @default.
• W2001231930 creator A5011309644 @default.
• W2001231930 creator A5016407136 @default.
• W2001231930 creator A5017468691 @default.
• W2001231930 creator A5026218314 @default.
• W2001231930 creator A5034586842 @default.
• W2001231930 creator A5056918776 @default.
• W2001231930 creator A5072574772 @default.
• W2001231930 creator A5089277393 @default.
• W2001231930 date "2011-11-01" @default.
• W2001231930 modified "2023-10-01" @default.
• W2001231930 title "Predictors of Long-Term Toxicity Using Three-Dimensional Conformal External Beam Radiotherapy to Deliver Accelerated Partial Breast Irradiation" @default.
• W2001231930 cites W1576120608 @default.
• W2001231930 cites W1967377484 @default.
• W2001231930 cites W1976367403 @default.
• W2001231930 cites W1979556233 @default.
• W2001231930 cites W2015481942 @default.
• W2001231930 cites W2046516657 @default.
• W2001231930 cites W2047702653 @default.
• W2001231930 cites W2059243286 @default.
• W2001231930 cites W2060841536 @default.
• W2001231930 cites W2095213003 @default.
• W2001231930 cites W2144968526 @default.
• W2001231930 cites W2145380278 @default.
• W2001231930 cites W2156554745 @default.
• W2001231930 cites W2167916669 @default.
• W2001231930 cites W3023367896 @default.
• W2001231930 doi "https://doi.org/10.1016/j.ijrobp.2010.06.062" @default.
• W2001231930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20933342" @default.
• W2001231930 hasPublicationYear "2011" @default.
• W2001231930 type Work @default.
• W2001231930 sameAs 2001231930 @default.
• W2001231930 citedByCount "22" @default.
• W2001231930 countsByYear W20012319302012 @default.
• W2001231930 countsByYear W20012319302013 @default.
• W2001231930 countsByYear W20012319302014 @default.
• W2001231930 countsByYear W20012319302015 @default.
• W2001231930 countsByYear W20012319302017 @default.
• W2001231930 countsByYear W20012319302018 @default.
• W2001231930 countsByYear W20012319302020 @default.
• W2001231930 countsByYear W20012319302021 @default.
• W2001231930 countsByYear W20012319302023 @default.
• W2001231930 crossrefType "journal-article" @default.
• W2001231930 hasAuthorship W2001231930A5011309644 @default.
• W2001231930 hasAuthorship W2001231930A5016407136 @default.
• W2001231930 hasAuthorship W2001231930A5017468691 @default.
• W2001231930 hasAuthorship W2001231930A5026218314 @default.
• W2001231930 hasAuthorship W2001231930A5034586842 @default.
• W2001231930 hasAuthorship W2001231930A5056918776 @default.
• W2001231930 hasAuthorship W2001231930A5072574772 @default.
• W2001231930 hasAuthorship W2001231930A5089277393 @default.
• W2001231930 hasConcept C121608353 @default.
• W2001231930 hasConcept C126322002 @default.
• W2001231930 hasConcept C126838900 @default.
• W2001231930 hasConcept C141071460 @default.
• W2001231930 hasConcept C2776330896 @default.
• W2001231930 hasConcept C2777757722 @default.
• W2001231930 hasConcept C2777793932 @default.
• W2001231930 hasConcept C2779572924 @default.
• W2001231930 hasConcept C2780932660 @default.
• W2001231930 hasConcept C2780943399 @default.
• W2001231930 hasConcept C29730261 @default.
• W2001231930 hasConcept C2989005 @default.
• W2001231930 hasConcept C509974204 @default.
• W2001231930 hasConcept C530470458 @default.
• W2001231930 hasConcept C71924100 @default.
• W2001231930 hasConceptScore W2001231930C121608353 @default.
• W2001231930 hasConceptScore W2001231930C126322002 @default.
• W2001231930 hasConceptScore W2001231930C126838900 @default.
• W2001231930 hasConceptScore W2001231930C141071460 @default.
• W2001231930 hasConceptScore W2001231930C2776330896 @default.
• W2001231930 hasConceptScore W2001231930C2777757722 @default.
• W2001231930 hasConceptScore W2001231930C2777793932 @default.
• W2001231930 hasConceptScore W2001231930C2779572924 @default.
• W2001231930 hasConceptScore W2001231930C2780932660 @default.
• W2001231930 hasConceptScore W2001231930C2780943399 @default.
• W2001231930 hasConceptScore W2001231930C29730261 @default.
• W2001231930 hasConceptScore W2001231930C2989005 @default.
• W2001231930 hasConceptScore W2001231930C509974204 @default.
• W2001231930 hasConceptScore W2001231930C530470458 @default.
• W2001231930 hasConceptScore W2001231930C71924100 @default.
• W2001231930 hasIssue "3" @default.
• W2001231930 hasLocation W20012319301 @default.
• W2001231930 hasLocation W20012319302 @default.
• W2001231930 hasOpenAccess W2001231930 @default.
• W2001231930 hasPrimaryLocation W20012319301 @default.
• W2001231930 hasRelatedWork W2001231930 @default.
• W2001231930 hasRelatedWork W2021030121 @default.
• W2001231930 hasRelatedWork W2028720836 @default.
• W2001231930 hasRelatedWork W2029482052 @default.
• W2001231930 hasRelatedWork W2059347310 @default.
• W2001231930 hasRelatedWork W2079457655 @default.
• W2001231930 hasRelatedWork W2171057830 @default.
• W2001231930 hasRelatedWork W2417530735 @default.
• W2001231930 hasRelatedWork W273545074 @default.
• W2001231930 hasRelatedWork W3007875326 @default.
• W2001231930 hasVolume "81" @default.

• next