FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001232700> ?p ?o ?g. }

• W2001232700 endingPage "2586" @default.
• W2001232700 startingPage "2585" @default.
• W2001232700 abstract "Protozoic infections caused by genus Leishmania pose an enormous public health threat in developing countries, compounded by the toxicity and resistance to current therapies. Under the aegis of our ongoing program on drug discovery and development on antileishmanial agents from plants, we carried out bioassay guided fractionation on Peganum harmala seeds which resulted in the isolation of 1 as an antileishmanial agent. 2D-NMR spectral data and single crystal X-ray crystallography data indicated 1 as peganine hydrochloride in dihydrated form. The compound 1 exhibited in-vitro activity against both extracellular promastigotes as well as intracellular amastigotes residing within murine macrophages in Leishmania donovani. Furthermore, 1 also exhibited in-vivo activity, 79.6 (±8.07)% against established VL in hamsters at a dose of 100 mg/kg b.wt." @default.
• W2001232700 created "2016-06-24" @default.
• W2001232700 creator A5037037802 @default.
• W2001232700 creator A5050206308 @default.
• W2001232700 creator A5057111603 @default.
• W2001232700 creator A5059221709 @default.
• W2001232700 creator A5070437118 @default.
• W2001232700 creator A5075946768 @default.
• W2001232700 creator A5076603228 @default.
• W2001232700 creator A5089616570 @default.
• W2001232700 date "2009-05-01" @default.
• W2001232700 modified "2023-10-18" @default.
• W2001232700 title "Peganine hydrochloride dihydrate an orally active antileishmanial agent" @default.
• W2001232700 cites W1988325991 @default.
• W2001232700 cites W2000335433 @default.
• W2001232700 cites W2001941127 @default.
• W2001232700 cites W2003104596 @default.
• W2001232700 cites W2004537227 @default.
• W2001232700 cites W2014662504 @default.
• W2001232700 cites W2077946350 @default.
• W2001232700 cites W2093871819 @default.
• W2001232700 cites W2140378376 @default.
• W2001232700 cites W2150196410 @default.
• W2001232700 cites W2163456506 @default.
• W2001232700 doi "https://doi.org/10.1016/j.bmcl.2009.03.039" @default.
• W2001232700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19339182" @default.
• W2001232700 hasPublicationYear "2009" @default.
• W2001232700 type Work @default.
• W2001232700 sameAs 2001232700 @default.
• W2001232700 citedByCount "36" @default.
• W2001232700 countsByYear W20012327002012 @default.
• W2001232700 countsByYear W20012327002013 @default.
• W2001232700 countsByYear W20012327002014 @default.
• W2001232700 countsByYear W20012327002015 @default.
• W2001232700 countsByYear W20012327002016 @default.
• W2001232700 countsByYear W20012327002017 @default.
• W2001232700 countsByYear W20012327002018 @default.
• W2001232700 countsByYear W20012327002019 @default.
• W2001232700 countsByYear W20012327002020 @default.
• W2001232700 countsByYear W20012327002021 @default.
• W2001232700 countsByYear W20012327002022 @default.
• W2001232700 crossrefType "journal-article" @default.
• W2001232700 hasAuthorship W2001232700A5037037802 @default.
• W2001232700 hasAuthorship W2001232700A5050206308 @default.
• W2001232700 hasAuthorship W2001232700A5057111603 @default.
• W2001232700 hasAuthorship W2001232700A5059221709 @default.
• W2001232700 hasAuthorship W2001232700A5070437118 @default.
• W2001232700 hasAuthorship W2001232700A5075946768 @default.
• W2001232700 hasAuthorship W2001232700A5076603228 @default.
• W2001232700 hasAuthorship W2001232700A5089616570 @default.
• W2001232700 hasConcept C104488531 @default.
• W2001232700 hasConcept C116073593 @default.
• W2001232700 hasConcept C136764020 @default.
• W2001232700 hasConcept C150903083 @default.
• W2001232700 hasConcept C160492267 @default.
• W2001232700 hasConcept C178790620 @default.
• W2001232700 hasConcept C185592680 @default.
• W2001232700 hasConcept C202751555 @default.
• W2001232700 hasConcept C203014093 @default.
• W2001232700 hasConcept C207001950 @default.
• W2001232700 hasConcept C2776460385 @default.
• W2001232700 hasConcept C2776555147 @default.
• W2001232700 hasConcept C2778689377 @default.
• W2001232700 hasConcept C2780237542 @default.
• W2001232700 hasConcept C2781092759 @default.
• W2001232700 hasConcept C2781333301 @default.
• W2001232700 hasConcept C29730261 @default.
• W2001232700 hasConcept C41008148 @default.
• W2001232700 hasConcept C54355233 @default.
• W2001232700 hasConcept C55493867 @default.
• W2001232700 hasConcept C556039675 @default.
• W2001232700 hasConcept C71924100 @default.
• W2001232700 hasConcept C71928629 @default.
• W2001232700 hasConcept C86803240 @default.
• W2001232700 hasConcept C98274493 @default.
• W2001232700 hasConcept C98319499 @default.
• W2001232700 hasConceptScore W2001232700C104488531 @default.
• W2001232700 hasConceptScore W2001232700C116073593 @default.
• W2001232700 hasConceptScore W2001232700C136764020 @default.
• W2001232700 hasConceptScore W2001232700C150903083 @default.
• W2001232700 hasConceptScore W2001232700C160492267 @default.
• W2001232700 hasConceptScore W2001232700C178790620 @default.
• W2001232700 hasConceptScore W2001232700C185592680 @default.
• W2001232700 hasConceptScore W2001232700C202751555 @default.
• W2001232700 hasConceptScore W2001232700C203014093 @default.
• W2001232700 hasConceptScore W2001232700C207001950 @default.
• W2001232700 hasConceptScore W2001232700C2776460385 @default.
• W2001232700 hasConceptScore W2001232700C2776555147 @default.
• W2001232700 hasConceptScore W2001232700C2778689377 @default.
• W2001232700 hasConceptScore W2001232700C2780237542 @default.
• W2001232700 hasConceptScore W2001232700C2781092759 @default.
• W2001232700 hasConceptScore W2001232700C2781333301 @default.
• W2001232700 hasConceptScore W2001232700C29730261 @default.
• W2001232700 hasConceptScore W2001232700C41008148 @default.
• W2001232700 hasConceptScore W2001232700C54355233 @default.
• W2001232700 hasConceptScore W2001232700C55493867 @default.
• W2001232700 hasConceptScore W2001232700C556039675 @default.
• W2001232700 hasConceptScore W2001232700C71924100 @default.

• next