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- W2001242488 abstract "Type 2 diabetes mellitus and comorbidities related to overweight/obesity are risk factors for the development of cardiovascular disease (CVD). In addition to insulin resistance and progressive beta-cell failure as key factors in the pathogenesis of type 2 diabetes mellitus, defects in the incretin system are now known to contribute as well. Lifestyle modifications including diet and exercise are often insufficient for reducing glucose and weight, and most patients with type 2 diabetes will require pharmacotherapy to treat their hyperglycemia. Goals of therapy should be to reduce blood glucose to as low as possible, for as long as possible, without weight gain and hypoglycemia, and correcting cardiovascular risk factors. Numerous antidiabetes medications lower blood glucose; however, many are associated with weight gain and do not address risk factors present for CVD. Newer pharmacotherapies include the glucagon-like peptide-1 (GLP-1) receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and amylinomimetics. The GLP-1 receptor agonists and amylinomimetics reduce glucose while promoting weight loss and improving other cardiovascular risk factors with a low incidence of hypoglycemia. The DPP-4 inhibitors effectively lower glucose and are weight neutral." @default.
- W2001242488 created "2016-06-24" @default.
- W2001242488 creator A5004471830 @default.
- W2001242488 date "2010-01-01" @default.
- W2001242488 modified "2023-09-24" @default.
- W2001242488 title "Therapeutic Options that Provide Glycemic Control and Weight Loss for Patients with Type 2 Diabetes" @default.
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- W2001242488 cites W1526927233 @default.
- W2001242488 cites W1585447752 @default.
- W2001242488 cites W172609984 @default.
- W2001242488 cites W1946491572 @default.
- W2001242488 cites W1967012457 @default.
- W2001242488 cites W1970125713 @default.
- W2001242488 cites W1971471384 @default.
- W2001242488 cites W1972842959 @default.
- W2001242488 cites W1976287166 @default.
- W2001242488 cites W1977009119 @default.
- W2001242488 cites W1984740259 @default.
- W2001242488 cites W1985634496 @default.
- W2001242488 cites W1986085856 @default.
- W2001242488 cites W1994636940 @default.
- W2001242488 cites W1994743271 @default.
- W2001242488 cites W1998727533 @default.
- W2001242488 cites W2008108208 @default.
- W2001242488 cites W2011499650 @default.
- W2001242488 cites W2012943708 @default.
- W2001242488 cites W2028272916 @default.
- W2001242488 cites W2044160793 @default.
- W2001242488 cites W2045554373 @default.
- W2001242488 cites W2047864863 @default.
- W2001242488 cites W2050826565 @default.
- W2001242488 cites W2051462052 @default.
- W2001242488 cites W2052329109 @default.
- W2001242488 cites W2056730663 @default.
- W2001242488 cites W2062883844 @default.
- W2001242488 cites W2063454212 @default.
- W2001242488 cites W2071835038 @default.
- W2001242488 cites W2082724449 @default.
- W2001242488 cites W2085862152 @default.
- W2001242488 cites W2087825440 @default.
- W2001242488 cites W2098459806 @default.
- W2001242488 cites W2101246901 @default.
- W2001242488 cites W2101613382 @default.
- W2001242488 cites W2102108180 @default.
- W2001242488 cites W2103058881 @default.
- W2001242488 cites W2103516789 @default.
- W2001242488 cites W2106154942 @default.
- W2001242488 cites W2106774879 @default.
- W2001242488 cites W2109728760 @default.
- W2001242488 cites W2111504946 @default.
- W2001242488 cites W2114392594 @default.
- W2001242488 cites W2114626270 @default.
- W2001242488 cites W2123946565 @default.
- W2001242488 cites W2129377335 @default.
- W2001242488 cites W2129578585 @default.
- W2001242488 cites W2129903164 @default.
- W2001242488 cites W2131278438 @default.
- W2001242488 cites W2138077952 @default.
- W2001242488 cites W2138290933 @default.
- W2001242488 cites W2143946880 @default.
- W2001242488 cites W2145335273 @default.
- W2001242488 cites W2146901298 @default.
- W2001242488 cites W2148798434 @default.
- W2001242488 cites W2152569314 @default.
- W2001242488 cites W2158666727 @default.
- W2001242488 cites W2158727328 @default.
- W2001242488 cites W2159205789 @default.
- W2001242488 cites W2160001758 @default.
- W2001242488 cites W2160423442 @default.
- W2001242488 cites W2161474086 @default.
- W2001242488 cites W2161551526 @default.
- W2001242488 cites W2162934281 @default.
- W2001242488 cites W2164416879 @default.
- W2001242488 cites W2170606300 @default.
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- W2001242488 cites W2171667655 @default.
- W2001242488 cites W2172221709 @default.
- W2001242488 cites W2181092548 @default.
- W2001242488 cites W2188846692 @default.
- W2001242488 cites W2228488234 @default.
- W2001242488 cites W2337454357 @default.
- W2001242488 cites W2626017884 @default.
- W2001242488 cites W4250936128 @default.
- W2001242488 cites W2113901579 @default.
- W2001242488 doi "https://doi.org/10.3810/pgm.2010.01.2111" @default.
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