Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001267258> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2001267258 endingPage "S33" @default.
- W2001267258 startingPage "S30" @default.
- W2001267258 abstract "<h2>Abstract</h2> Infertility affects approximately 10–15% of couples. To enhance the chances of conception, assisted reproductive techniques (ART) have been improved and, in the last 5 years, thousands of babies have been delivered after IVF or ICSI procedures. To obtain an appropriate and controlled ovarian hyperstimulation (COH), clinicians have introduced many drug protocols based on GnRH agonists or antagonists for pituitary down-regulation and FSH or HMG for ovarian stimulation. Currently FSH is the most common drug used for ovulation induction. It is a glycosylated protein with a molecular weight of 28000–30000Da, normally secreted by the anterior pituitary gland. The recombinant preparations of follicle stimulation hormone (r-FSH) are characterized by a higher level of purity, reduced batch to batch variability and no risk of infection. The purpose of this review was to establish the efficacy of different trials based on the use of r-FSH and urinary FSH (u-FSH) comparing published data from randomised studies on the ovulation induction for assisted reproductive techniques. Unfortunately, we did not find any paper with sufficient power to detect a clinically significant difference in pregnancy rates, however, recent meta-analysis among homogeneous trials indicates that the use of r-FSH is to be preferred to u-FSH because more oocytes were collected in cycles with better embryo quality and with more pregnancies. Recombinant FSH has a higher cost per ampoule than urinary FSH, but also a higher effectiveness. A recent cost-effectiveness analysis on follitropin alfa compared to urinary FSH-HP, using a Markov model, confirmed other previous studies that, considering the ongoing pregnancies beyond 12 weeks gestation, r-FSH is the most effective therapy for ovulation induction in ART." @default.
- W2001267258 created "2016-06-24" @default.
- W2001267258 creator A5034316395 @default.
- W2001267258 creator A5044760713 @default.
- W2001267258 creator A5073022475 @default.
- W2001267258 date "2004-07-01" @default.
- W2001267258 modified "2023-09-24" @default.
- W2001267258 title "FSH: urinary and recombinant" @default.
- W2001267258 cites W2004337058 @default.
- W2001267258 cites W2028537306 @default.
- W2001267258 cites W2036243110 @default.
- W2001267258 cites W2060022009 @default.
- W2001267258 cites W2063367908 @default.
- W2001267258 cites W2067900905 @default.
- W2001267258 cites W2081515628 @default.
- W2001267258 cites W2091186738 @default.
- W2001267258 cites W2100938534 @default.
- W2001267258 cites W2103428431 @default.
- W2001267258 cites W2132265062 @default.
- W2001267258 cites W2133706544 @default.
- W2001267258 cites W2139084383 @default.
- W2001267258 cites W2141503011 @default.
- W2001267258 cites W2158135128 @default.
- W2001267258 cites W2241273299 @default.
- W2001267258 cites W4252995375 @default.
- W2001267258 doi "https://doi.org/10.1016/j.ejogrb.2004.01.023" @default.
- W2001267258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15196713" @default.
- W2001267258 hasPublicationYear "2004" @default.
- W2001267258 type Work @default.
- W2001267258 sameAs 2001267258 @default.
- W2001267258 citedByCount "15" @default.
- W2001267258 countsByYear W20012672582012 @default.
- W2001267258 countsByYear W20012672582013 @default.
- W2001267258 countsByYear W20012672582015 @default.
- W2001267258 countsByYear W20012672582019 @default.
- W2001267258 countsByYear W20012672582021 @default.
- W2001267258 countsByYear W20012672582022 @default.
- W2001267258 crossrefType "journal-article" @default.
- W2001267258 hasAuthorship W2001267258A5034316395 @default.
- W2001267258 hasAuthorship W2001267258A5044760713 @default.
- W2001267258 hasAuthorship W2001267258A5073022475 @default.
- W2001267258 hasConcept C126322002 @default.
- W2001267258 hasConcept C134018914 @default.
- W2001267258 hasConcept C16685009 @default.
- W2001267258 hasConcept C2777688143 @default.
- W2001267258 hasConcept C2777702977 @default.
- W2001267258 hasConcept C2778478619 @default.
- W2001267258 hasConcept C2778575703 @default.
- W2001267258 hasConcept C2778580812 @default.
- W2001267258 hasConcept C2778782382 @default.
- W2001267258 hasConcept C2779234561 @default.
- W2001267258 hasConcept C2779279165 @default.
- W2001267258 hasConcept C2781230225 @default.
- W2001267258 hasConcept C29456083 @default.
- W2001267258 hasConcept C54355233 @default.
- W2001267258 hasConcept C71315377 @default.
- W2001267258 hasConcept C71924100 @default.
- W2001267258 hasConcept C77411442 @default.
- W2001267258 hasConcept C86803240 @default.
- W2001267258 hasConceptScore W2001267258C126322002 @default.
- W2001267258 hasConceptScore W2001267258C134018914 @default.
- W2001267258 hasConceptScore W2001267258C16685009 @default.
- W2001267258 hasConceptScore W2001267258C2777688143 @default.
- W2001267258 hasConceptScore W2001267258C2777702977 @default.
- W2001267258 hasConceptScore W2001267258C2778478619 @default.
- W2001267258 hasConceptScore W2001267258C2778575703 @default.
- W2001267258 hasConceptScore W2001267258C2778580812 @default.
- W2001267258 hasConceptScore W2001267258C2778782382 @default.
- W2001267258 hasConceptScore W2001267258C2779234561 @default.
- W2001267258 hasConceptScore W2001267258C2779279165 @default.
- W2001267258 hasConceptScore W2001267258C2781230225 @default.
- W2001267258 hasConceptScore W2001267258C29456083 @default.
- W2001267258 hasConceptScore W2001267258C54355233 @default.
- W2001267258 hasConceptScore W2001267258C71315377 @default.
- W2001267258 hasConceptScore W2001267258C71924100 @default.
- W2001267258 hasConceptScore W2001267258C77411442 @default.
- W2001267258 hasConceptScore W2001267258C86803240 @default.
- W2001267258 hasLocation W20012672581 @default.
- W2001267258 hasLocation W20012672582 @default.
- W2001267258 hasOpenAccess W2001267258 @default.
- W2001267258 hasPrimaryLocation W20012672581 @default.
- W2001267258 hasRelatedWork W1746903759 @default.
- W2001267258 hasRelatedWork W2019269244 @default.
- W2001267258 hasRelatedWork W2060022009 @default.
- W2001267258 hasRelatedWork W2126135101 @default.
- W2001267258 hasRelatedWork W2156548859 @default.
- W2001267258 hasRelatedWork W2170775580 @default.
- W2001267258 hasRelatedWork W2967472330 @default.
- W2001267258 hasRelatedWork W79409830 @default.
- W2001267258 hasRelatedWork W2100861453 @default.
- W2001267258 hasRelatedWork W2423692752 @default.
- W2001267258 hasVolume "115" @default.
- W2001267258 isParatext "false" @default.
- W2001267258 isRetracted "false" @default.
- W2001267258 magId "2001267258" @default.
- W2001267258 workType "article" @default.