FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001330472> ?p ?o ?g. }

• W2001330472 endingPage "6446" @default.
• W2001330472 startingPage "6442" @default.
• W2001330472 abstract "We have purified a stimulatory GDP/GTP exchange protein for smg p21A and -B, ras p21-like small GTP-binding proteins (G proteins), cloned its cDNA, and named it GDP dissociation stimulator (smg p21 GDS). We show here that smg p21 GDS is active not only on smg p21A and -B but also on c-Ki-ras p21 and rhoA p21, all of which are post-translationally processed. Furthermore, we show that smg p21 GDS is inactive on the post-translationally unprocessed form of these proteins and on the post-translationally unprocessed form of c-Ha-ras p21 and smg p25A. All of the small G proteins recognized by smg p21 GDS have a cDNA-predicted C-terminal CAAX motif (where C is cysteine, A is an aliphatic amino acid, and X is any amino acid) and a polybasic region upstream of this motif. These results suggest that smg p21 GDS is at least active on a group of small G proteins having these unique C-terminal structures. Moreover, they suggest that the C-terminal post-translational processing of these small G proteins, by farnesylation or geranylgeranylation of the C-terminal cysteine residue, removal of amino acids in positions denoted AAX, and carboxyl methylation of the exposed cysteine residue, is important for the smg p21 GDS action." @default.
• W2001330472 created "2016-06-24" @default.
• W2001330472 creator A5012487815 @default.
• W2001330472 creator A5037548640 @default.
• W2001330472 creator A5039208853 @default.
• W2001330472 creator A5042331400 @default.
• W2001330472 creator A5078148464 @default.
• W2001330472 creator A5081757857 @default.
• W2001330472 creator A5087837717 @default.
• W2001330472 creator A5088758930 @default.
• W2001330472 date "1991-08-01" @default.
• W2001330472 modified "2023-10-01" @default.
• W2001330472 title "A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21." @default.
• W2001330472 cites W1490645937 @default.
• W2001330472 cites W1499361685 @default.
• W2001330472 cites W1506293995 @default.
• W2001330472 cites W1517753349 @default.
• W2001330472 cites W1519439704 @default.
• W2001330472 cites W1528733643 @default.
• W2001330472 cites W1543554885 @default.
• W2001330472 cites W1556741602 @default.
• W2001330472 cites W1561770236 @default.
• W2001330472 cites W1582088706 @default.
• W2001330472 cites W1607692727 @default.
• W2001330472 cites W1656440259 @default.
• W2001330472 cites W1841319127 @default.
• W2001330472 cites W1980865411 @default.
• W2001330472 cites W1982461852 @default.
• W2001330472 cites W1993400755 @default.
• W2001330472 cites W2002141015 @default.
• W2001330472 cites W2004755394 @default.
• W2001330472 cites W2005189737 @default.
• W2001330472 cites W2012005366 @default.
• W2001330472 cites W2013575623 @default.
• W2001330472 cites W2039246692 @default.
• W2001330472 cites W2043921136 @default.
• W2001330472 cites W2045500858 @default.
• W2001330472 cites W2057724275 @default.
• W2001330472 cites W2085595729 @default.
• W2001330472 cites W2094916229 @default.
• W2001330472 cites W2095581687 @default.
• W2001330472 cites W2111188818 @default.
• W2001330472 cites W2142953182 @default.
• W2001330472 cites W2270306924 @default.
• W2001330472 cites W2302025612 @default.
• W2001330472 cites W2410890949 @default.
• W2001330472 cites W2417737999 @default.
• W2001330472 cites W4232777855 @default.
• W2001330472 cites W69400297 @default.
• W2001330472 doi "https://doi.org/10.1073/pnas.88.15.6442" @default.
• W2001330472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/52101" @default.
• W2001330472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1907371" @default.
• W2001330472 hasPublicationYear "1991" @default.
• W2001330472 type Work @default.
• W2001330472 sameAs 2001330472 @default.
• W2001330472 citedByCount "189" @default.
• W2001330472 countsByYear W20013304722012 @default.
• W2001330472 countsByYear W20013304722013 @default.
• W2001330472 countsByYear W20013304722014 @default.
• W2001330472 countsByYear W20013304722015 @default.
• W2001330472 countsByYear W20013304722017 @default.
• W2001330472 countsByYear W20013304722018 @default.
• W2001330472 countsByYear W20013304722019 @default.
• W2001330472 countsByYear W20013304722020 @default.
• W2001330472 countsByYear W20013304722021 @default.
• W2001330472 countsByYear W20013304722023 @default.
• W2001330472 crossrefType "journal-article" @default.
• W2001330472 hasAuthorship W2001330472A5012487815 @default.
• W2001330472 hasAuthorship W2001330472A5037548640 @default.
• W2001330472 hasAuthorship W2001330472A5039208853 @default.
• W2001330472 hasAuthorship W2001330472A5042331400 @default.
• W2001330472 hasAuthorship W2001330472A5078148464 @default.
• W2001330472 hasAuthorship W2001330472A5081757857 @default.
• W2001330472 hasAuthorship W2001330472A5087837717 @default.
• W2001330472 hasAuthorship W2001330472A5088758930 @default.
• W2001330472 hasBestOaLocation W20013304722 @default.
• W2001330472 hasConcept C104317684 @default.
• W2001330472 hasConcept C118716 @default.
• W2001330472 hasConcept C181199279 @default.
• W2001330472 hasConcept C185592680 @default.
• W2001330472 hasConcept C187882448 @default.
• W2001330472 hasConcept C2776638253 @default.
• W2001330472 hasConcept C2777093181 @default.
• W2001330472 hasConcept C2779201268 @default.
• W2001330472 hasConcept C2779817904 @default.
• W2001330472 hasConcept C2781335528 @default.
• W2001330472 hasConcept C515207424 @default.
• W2001330472 hasConcept C55493867 @default.
• W2001330472 hasConcept C57790582 @default.
• W2001330472 hasConcept C62478195 @default.
• W2001330472 hasConcept C86803240 @default.
• W2001330472 hasConceptScore W2001330472C104317684 @default.
• W2001330472 hasConceptScore W2001330472C118716 @default.
• W2001330472 hasConceptScore W2001330472C181199279 @default.
• W2001330472 hasConceptScore W2001330472C185592680 @default.
• W2001330472 hasConceptScore W2001330472C187882448 @default.
• W2001330472 hasConceptScore W2001330472C2776638253 @default.
• W2001330472 hasConceptScore W2001330472C2777093181 @default.

• next