Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001363611> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2001363611 endingPage "9" @default.
- W2001363611 startingPage "1" @default.
- W2001363611 abstract "The antiobesity effects of Codonopsis lanceolata (CL) were evaluated in a high-calorie/high-fat-diet (HFD-) induced obesity rat model and 3T3-L1 cells. The Sprague-Dawley male rats were fed a normal diet (ND) or a HFD for a period of 12 weeks. The rats were subdivided into groups: ND, ND + wild Codonopsis lanceolata (wCL) (900 mg/kg/day, p.o.), ND + cultivated Codonopsis lanceolata (cCL) (900 mg/kg/day, p.o.), HFD, HFD + wCL (100, 300, or 900 mg/kg/day, p.o.), HFD + cCL (100, 300, or 900 mg/kg/day, p.o.), and HFD + sibutramine. The body weight gains of the administered HFD + CL (wCL or CCL) were lower than those of the rats fed with only the HFD group. Moreover, the weight of adipose pads and the serum levels of triglycerides, total cholesterol, and low density lipoprotein cholesterol in the group administered HDL + CL were significantly lower than in the HFD group. The inhibitory effect of lipid accumulation in 3T3-L1 cells was measured by Oil Red O staining and reverse transcription-polymerase chain reaction (RT-PCR). Treatment of 3T3-L1 cells with wCL inhibited lipid accumulation and expression of C/EBP<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>α</mml:mi></mml:mrow></mml:math>and PPAR<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mi>γ</mml:mi></mml:mrow></mml:math>. These results suggest that CL has a great potential as a functional food with anti-obesity effects and as a therapeutic alternative in the treatment of obesity." @default.
- W2001363611 created "2016-06-24" @default.
- W2001363611 creator A5009429584 @default.
- W2001363611 creator A5015164764 @default.
- W2001363611 creator A5068293693 @default.
- W2001363611 creator A5075676556 @default.
- W2001363611 date "2013-01-01" @default.
- W2001363611 modified "2023-10-05" @default.
- W2001363611 title "Antiobesity Effect of<i>Codonopsis lanceolata</i>in High-Calorie/High-Fat-Diet-Induced Obese Rats" @default.
- W2001363611 cites W1552362051 @default.
- W2001363611 cites W1881728045 @default.
- W2001363611 cites W1907219612 @default.
- W2001363611 cites W1964363469 @default.
- W2001363611 cites W1968703258 @default.
- W2001363611 cites W1969382600 @default.
- W2001363611 cites W1981086510 @default.
- W2001363611 cites W1988069415 @default.
- W2001363611 cites W2002009920 @default.
- W2001363611 cites W2006951646 @default.
- W2001363611 cites W2009977883 @default.
- W2001363611 cites W2022996519 @default.
- W2001363611 cites W2028879197 @default.
- W2001363611 cites W2032060159 @default.
- W2001363611 cites W2038462957 @default.
- W2001363611 cites W2048896208 @default.
- W2001363611 cites W2064305279 @default.
- W2001363611 cites W2068326309 @default.
- W2001363611 cites W2071692398 @default.
- W2001363611 cites W2072410011 @default.
- W2001363611 cites W2073128218 @default.
- W2001363611 cites W2127785815 @default.
- W2001363611 cites W2128924329 @default.
- W2001363611 cites W2150667463 @default.
- W2001363611 cites W4231523688 @default.
- W2001363611 doi "https://doi.org/10.1155/2013/210297" @default.
- W2001363611 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3683442" @default.
- W2001363611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23818922" @default.
- W2001363611 hasPublicationYear "2013" @default.
- W2001363611 type Work @default.
- W2001363611 sameAs 2001363611 @default.
- W2001363611 citedByCount "25" @default.
- W2001363611 countsByYear W20013636112014 @default.
- W2001363611 countsByYear W20013636112015 @default.
- W2001363611 countsByYear W20013636112016 @default.
- W2001363611 countsByYear W20013636112017 @default.
- W2001363611 countsByYear W20013636112018 @default.
- W2001363611 countsByYear W20013636112019 @default.
- W2001363611 countsByYear W20013636112020 @default.
- W2001363611 countsByYear W20013636112021 @default.
- W2001363611 countsByYear W20013636112022 @default.
- W2001363611 crossrefType "journal-article" @default.
- W2001363611 hasAuthorship W2001363611A5009429584 @default.
- W2001363611 hasAuthorship W2001363611A5015164764 @default.
- W2001363611 hasAuthorship W2001363611A5068293693 @default.
- W2001363611 hasAuthorship W2001363611A5075676556 @default.
- W2001363611 hasBestOaLocation W20013636111 @default.
- W2001363611 hasConcept C126322002 @default.
- W2001363611 hasConcept C134018914 @default.
- W2001363611 hasConcept C142724271 @default.
- W2001363611 hasConcept C171089720 @default.
- W2001363611 hasConcept C185592680 @default.
- W2001363611 hasConcept C188947578 @default.
- W2001363611 hasConcept C204787440 @default.
- W2001363611 hasConcept C2778505178 @default.
- W2001363611 hasConcept C71924100 @default.
- W2001363611 hasConceptScore W2001363611C126322002 @default.
- W2001363611 hasConceptScore W2001363611C134018914 @default.
- W2001363611 hasConceptScore W2001363611C142724271 @default.
- W2001363611 hasConceptScore W2001363611C171089720 @default.
- W2001363611 hasConceptScore W2001363611C185592680 @default.
- W2001363611 hasConceptScore W2001363611C188947578 @default.
- W2001363611 hasConceptScore W2001363611C204787440 @default.
- W2001363611 hasConceptScore W2001363611C2778505178 @default.
- W2001363611 hasConceptScore W2001363611C71924100 @default.
- W2001363611 hasLocation W20013636111 @default.
- W2001363611 hasLocation W20013636112 @default.
- W2001363611 hasLocation W20013636113 @default.
- W2001363611 hasLocation W20013636114 @default.
- W2001363611 hasLocation W20013636115 @default.
- W2001363611 hasOpenAccess W2001363611 @default.
- W2001363611 hasPrimaryLocation W20013636111 @default.
- W2001363611 hasRelatedWork W1964688190 @default.
- W2001363611 hasRelatedWork W1976234278 @default.
- W2001363611 hasRelatedWork W1978718098 @default.
- W2001363611 hasRelatedWork W2017606817 @default.
- W2001363611 hasRelatedWork W2027098794 @default.
- W2001363611 hasRelatedWork W2049045125 @default.
- W2001363611 hasRelatedWork W2071032213 @default.
- W2001363611 hasRelatedWork W2081564223 @default.
- W2001363611 hasRelatedWork W2167541966 @default.
- W2001363611 hasRelatedWork W4253482381 @default.
- W2001363611 hasVolume "2013" @default.
- W2001363611 isParatext "false" @default.
- W2001363611 isRetracted "false" @default.
- W2001363611 magId "2001363611" @default.
- W2001363611 workType "article" @default.