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- W2001382007 abstract "Background A high efficacy multi-stage multi-epitope malaria vaccine would be an invaluable weapon in the eradication of malaria. Currently, the best progress in subunit vaccine research has been seen in targeting pre-erythrocytic (PE) stages of the parasite. In phase IIa trials, RTS,S in adjuvant was capable of inducing sterile protection in 50% of individuals [1], and ME-TRAP in a heterologous prime-boost regime saw around 21% efficacy [2]. Here we present a mathematical model investigating the effects of combining these two approaches." @default.
- W2001382007 created "2016-06-24" @default.
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- W2001382007 date "2014-09-01" @default.
- W2001382007 modified "2023-10-14" @default.
- W2001382007 title "Modelling the effects of combining pre-erythrocytic vaccines against Plasmodium falciparum" @default.
- W2001382007 cites W2063937996 @default.
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- W2001382007 doi "https://doi.org/10.1186/1475-2875-13-s1-p90" @default.
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