FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001395014> ?p ?o ?g. }

• W2001395014 endingPage "1276" @default.
• W2001395014 startingPage "1261" @default.
• W2001395014 abstract "Kawasaki disease (KD) is the leading cause of acquired heart disease in children and can result in life-threatening coronary artery aneurysms in up to 25 % of patients. These aneurysms put patients at risk of thrombus formation, myocardial infarction, and sudden death. Clinicians must therefore decide which patients should be treated with anticoagulant medication, and/or surgical or percutaneous intervention. Current recommendations regarding initiation of anticoagulant therapy are based on anatomy alone with historical data suggesting that patients with aneurysms $$ge $$ 8 mm are at greatest risk of thrombosis. Given the multitude of variables that influence thrombus formation, we postulated that hemodynamic data derived from patient-specific simulations would more accurately predict risk of thrombosis than maximum diameter alone. Patient-specific blood flow simulations were performed on five KD patients with aneurysms and one KD patient with normal coronary arteries. Key hemodynamic and geometric parameters, including wall shear stress, particle residence time, and shape indices, were extracted from the models and simulations and compared with clinical outcomes. Preliminary fluid structure interaction simulations with radial expansion were performed, revealing modest differences in wall shear stress compared to the rigid wall case. Simulations provide compelling evidence that hemodynamic parameters may be a more accurate predictor of thrombotic risk than aneurysm diameter alone and motivate the need for follow-up studies with a larger cohort. These results suggest that a clinical index incorporating hemodynamic information be used in the future to select patients for anticoagulant therapy." @default.
• W2001395014 created "2016-06-24" @default.
• W2001395014 creator A5043440558 @default.
• W2001395014 creator A5065297743 @default.
• W2001395014 creator A5075348877 @default.
• W2001395014 creator A5080140214 @default.
• W2001395014 creator A5083650161 @default.
• W2001395014 creator A5083766821 @default.
• W2001395014 creator A5087790536 @default.
• W2001395014 creator A5089502168 @default.
• W2001395014 date "2014-04-11" @default.
• W2001395014 modified "2023-10-15" @default.
• W2001395014 title "Thrombotic risk stratification using computational modeling in patients with coronary artery aneurysms following Kawasaki disease" @default.
• W2001395014 cites W1561189761 @default.
• W2001395014 cites W1867296472 @default.
• W2001395014 cites W1965965942 @default.
• W2001395014 cites W1967168536 @default.
• W2001395014 cites W1972941444 @default.
• W2001395014 cites W1981225511 @default.
• W2001395014 cites W1983332762 @default.
• W2001395014 cites W1988557781 @default.
• W2001395014 cites W1992736458 @default.
• W2001395014 cites W2010666563 @default.
• W2001395014 cites W2030695996 @default.
• W2001395014 cites W2040049417 @default.
• W2001395014 cites W2049554061 @default.
• W2001395014 cites W2050203246 @default.
• W2001395014 cites W2050966310 @default.
• W2001395014 cites W2053863063 @default.
• W2001395014 cites W2062299875 @default.
• W2001395014 cites W2063554347 @default.
• W2001395014 cites W2064752806 @default.
• W2001395014 cites W2065591461 @default.
• W2001395014 cites W2067626478 @default.
• W2001395014 cites W2067824277 @default.
• W2001395014 cites W2070700786 @default.
• W2001395014 cites W2075648775 @default.
• W2001395014 cites W2080259805 @default.
• W2001395014 cites W2082213552 @default.
• W2001395014 cites W2091670800 @default.
• W2001395014 cites W2099311959 @default.
• W2001395014 cites W2101558308 @default.
• W2001395014 cites W2109389220 @default.
• W2001395014 cites W2111845264 @default.
• W2001395014 cites W2116463491 @default.
• W2001395014 cites W2118951490 @default.
• W2001395014 cites W2119737077 @default.
• W2001395014 cites W2125972369 @default.
• W2001395014 cites W2126212536 @default.
• W2001395014 cites W2126476406 @default.
• W2001395014 cites W2130744279 @default.
• W2001395014 cites W2133370274 @default.
• W2001395014 cites W2134514183 @default.
• W2001395014 cites W2146132623 @default.
• W2001395014 cites W2151113032 @default.
• W2001395014 cites W2152915227 @default.
• W2001395014 cites W2155144802 @default.
• W2001395014 cites W2155939240 @default.
• W2001395014 cites W2158251772 @default.
• W2001395014 cites W2167723092 @default.
• W2001395014 cites W2315160100 @default.
• W2001395014 cites W2407539580 @default.
• W2001395014 cites W3102889263 @default.
• W2001395014 doi "https://doi.org/10.1007/s10237-014-0570-z" @default.
• W2001395014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4990134" @default.
• W2001395014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24722951" @default.
• W2001395014 hasPublicationYear "2014" @default.
• W2001395014 type Work @default.
• W2001395014 sameAs 2001395014 @default.
• W2001395014 citedByCount "51" @default.
• W2001395014 countsByYear W20013950142014 @default.
• W2001395014 countsByYear W20013950142015 @default.
• W2001395014 countsByYear W20013950142016 @default.
• W2001395014 countsByYear W20013950142017 @default.
• W2001395014 countsByYear W20013950142018 @default.
• W2001395014 countsByYear W20013950142019 @default.
• W2001395014 countsByYear W20013950142020 @default.
• W2001395014 countsByYear W20013950142021 @default.
• W2001395014 countsByYear W20013950142022 @default.
• W2001395014 countsByYear W20013950142023 @default.
• W2001395014 crossrefType "journal-article" @default.
• W2001395014 hasAuthorship W2001395014A5043440558 @default.
• W2001395014 hasAuthorship W2001395014A5065297743 @default.
• W2001395014 hasAuthorship W2001395014A5075348877 @default.
• W2001395014 hasAuthorship W2001395014A5080140214 @default.
• W2001395014 hasAuthorship W2001395014A5083650161 @default.
• W2001395014 hasAuthorship W2001395014A5083766821 @default.
• W2001395014 hasAuthorship W2001395014A5087790536 @default.
• W2001395014 hasAuthorship W2001395014A5089502168 @default.
• W2001395014 hasBestOaLocation W20013950142 @default.
• W2001395014 hasConcept C126322002 @default.
• W2001395014 hasConcept C126838900 @default.
• W2001395014 hasConcept C141071460 @default.
• W2001395014 hasConcept C164705383 @default.
• W2001395014 hasConcept C178853913 @default.
• W2001395014 hasConcept C2776098176 @default.
• W2001395014 hasConcept C2776820930 @default.
• W2001395014 hasConcept C2778213512 @default.

• next