FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001467170> ?p ?o ?g. }

• W2001467170 endingPage "1111" @default.
• W2001467170 startingPage "1102" @default.
• W2001467170 abstract "The calibration of functional magnetic resonance imaging (fMRI) for the estimation of neuronal activation-induced changes in cerebral metabolic rate of oxygen (CMRO2) has been achieved through hypercapnic-induced iso-metabolic increases in cerebral blood flow (CBF). Hypercapnia (HC) has been traditionally implemented through alterations in the fixed inspired fractional concentrations of carbon dioxide (FICO2) without otherwise controlling end-tidal partial pressures of carbon dioxide (PETCO2) or oxygen (PETO2). There are several shortcomings to the use of this manual HC method that may be improved by using precise targeting of PETCO2 while maintaining iso-oxia. Similarly, precise control of blood gases can be used to induce isocapnic hyperoxia (HO) to reduce venous deoxyhaemoglobin (dHb) and thus increase BOLD signals, without appreciably altering CMRO2 or CBF. The aim of our study was to use precise end-tidal targeting to compare the calibration of BOLD signals under an isocapnic hyperoxic protocol (HOP) (rises in PETO2 to 140, 240 and 340 mm Hg from baseline) to that of an iso-oxic hypercapnic protocol (HCP) (rises in PETCO2 of 3, 5, 7 and 9 mm Hg from baseline). Nine healthy volunteers were imaged at 3 T while monitoring end-tidal gas concentrations and simultaneously measuring BOLD and CBF signals, via arterial spin labeling (ASL), during graded HCP and HOP, alternating with normocapnic states in a blocked experimental design. The variability of the calibration constant obtained under HOP (MHOP) was 0.3–0.5 that of the HCP one (MHCP). In addition, M-variances with precise gas targeting (MHCP and MHOP) were less than those reported in studies using traditional FICO2 and FIO2 methods (MHC and MHO, respectively). We conclude that precise controlled gas delivery markedly improves BOLD-calibration for fMRI studies of oxygen metabolism with both the HCP and the more precise HOP-alternative." @default.
• W2001467170 created "2016-06-24" @default.
• W2001467170 creator A5022689820 @default.
• W2001467170 creator A5075685296 @default.
• W2001467170 creator A5076737365 @default.
• W2001467170 date "2011-01-01" @default.
• W2001467170 modified "2023-09-23" @default.
• W2001467170 title "Improved fMRI calibration: Precisely controlled hyperoxic versus hypercapnic stimuli" @default.
• W2001467170 cites W1559053160 @default.
• W2001467170 cites W1642429626 @default.
• W2001467170 cites W1972819551 @default.
• W2001467170 cites W1974105735 @default.
• W2001467170 cites W1975938737 @default.
• W2001467170 cites W1977230663 @default.
• W2001467170 cites W1979698077 @default.
• W2001467170 cites W1983257773 @default.
• W2001467170 cites W1986308766 @default.
• W2001467170 cites W1988794652 @default.
• W2001467170 cites W1989788919 @default.
• W2001467170 cites W1994192509 @default.
• W2001467170 cites W1995539489 @default.
• W2001467170 cites W1999736503 @default.
• W2001467170 cites W2002137001 @default.
• W2001467170 cites W2003256029 @default.
• W2001467170 cites W2005317009 @default.
• W2001467170 cites W2006380283 @default.
• W2001467170 cites W2007830779 @default.
• W2001467170 cites W2008150821 @default.
• W2001467170 cites W2012209067 @default.
• W2001467170 cites W2013479466 @default.
• W2001467170 cites W2015513598 @default.
• W2001467170 cites W2016306388 @default.
• W2001467170 cites W2018228708 @default.
• W2001467170 cites W2025613729 @default.
• W2001467170 cites W2027311248 @default.
• W2001467170 cites W2034346613 @default.
• W2001467170 cites W2036158578 @default.
• W2001467170 cites W2036537915 @default.
• W2001467170 cites W2037353747 @default.
• W2001467170 cites W2037741611 @default.
• W2001467170 cites W2038590120 @default.
• W2001467170 cites W2039090332 @default.
• W2001467170 cites W2043561221 @default.
• W2001467170 cites W2050112450 @default.
• W2001467170 cites W2056022329 @default.
• W2001467170 cites W2056050988 @default.
• W2001467170 cites W2056795435 @default.
• W2001467170 cites W2060054488 @default.
• W2001467170 cites W2060318115 @default.
• W2001467170 cites W2061516627 @default.
• W2001467170 cites W2069360567 @default.
• W2001467170 cites W2072718340 @default.
• W2001467170 cites W2075514568 @default.
• W2001467170 cites W2082499355 @default.
• W2001467170 cites W2083939018 @default.
• W2001467170 cites W2091048186 @default.
• W2001467170 cites W2101967150 @default.
• W2001467170 cites W2106031669 @default.
• W2001467170 cites W2111670923 @default.
• W2001467170 cites W2114276034 @default.
• W2001467170 cites W2117140276 @default.
• W2001467170 cites W2119994688 @default.
• W2001467170 cites W2120800380 @default.
• W2001467170 cites W2122901111 @default.
• W2001467170 cites W2124913096 @default.
• W2001467170 cites W2132137740 @default.
• W2001467170 cites W2137547086 @default.
• W2001467170 cites W2139489378 @default.
• W2001467170 cites W2149953389 @default.
• W2001467170 cites W2152346792 @default.
• W2001467170 cites W2154020722 @default.
• W2001467170 cites W2158411431 @default.
• W2001467170 cites W2161484086 @default.
• W2001467170 cites W2162743455 @default.
• W2001467170 cites W2178591638 @default.
• W2001467170 cites W2341223505 @default.
• W2001467170 cites W2345842757 @default.
• W2001467170 cites W2470594653 @default.
• W2001467170 doi "https://doi.org/10.1016/j.neuroimage.2010.08.070" @default.
• W2001467170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20828623" @default.
• W2001467170 hasPublicationYear "2011" @default.
• W2001467170 type Work @default.
• W2001467170 sameAs 2001467170 @default.
• W2001467170 citedByCount "72" @default.
• W2001467170 countsByYear W20014671702012 @default.
• W2001467170 countsByYear W20014671702013 @default.
• W2001467170 countsByYear W20014671702014 @default.
• W2001467170 countsByYear W20014671702015 @default.
• W2001467170 countsByYear W20014671702016 @default.
• W2001467170 countsByYear W20014671702017 @default.
• W2001467170 countsByYear W20014671702018 @default.
• W2001467170 countsByYear W20014671702019 @default.
• W2001467170 countsByYear W20014671702020 @default.
• W2001467170 countsByYear W20014671702021 @default.
• W2001467170 countsByYear W20014671702022 @default.
• W2001467170 crossrefType "journal-article" @default.
• W2001467170 hasAuthorship W2001467170A5022689820 @default.
• W2001467170 hasAuthorship W2001467170A5075685296 @default.

• next