Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001489087> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2001489087 endingPage "434" @default.
- W2001489087 startingPage "428" @default.
- W2001489087 abstract "To investigate the predictors of monoclonal gammopathy of undetermined significance (MGUS) by considering not only the initial features but also the pattern of evolution of the M protein during the first years after diagnosis.This study consisted of 359 patients diagnosed as having MGUS at a single institution. Patients who showed a definite and progressive increase in their M protein size according to serum electrophoresis during the first 3 years of follow-up were considered to have evolving MGUS, whereas all others were considered to have nonevolving MGUS.Of the 359 patients, 330 had nonevolving MGUS, whereas 29 fulfilled the criteria for evolving MGUS. Overall, 32 patients developed malignant transformation. The progression rates at 10 and 20 years of follow-up for the evolving and the nonevolving types were 55% vs 10% and 80% vs 13%, respectively. Multivariate analysis revealed that the features significantly associated with a higher risk of progression were evolving MGUS (relative risk [RR], 12.14; P<.001), IgA MGUS (RR, 2.93; P=.006), and M protein concentration (RR, 2.18; P=.04).The evolutionary pattern of serum M protein (progressive increasing vs stable) during the first years of follow-up is the most important risk factor for disease progression in patients with MGUS." @default.
- W2001489087 created "2016-06-24" @default.
- W2001489087 creator A5008706897 @default.
- W2001489087 creator A5015898454 @default.
- W2001489087 creator A5017225753 @default.
- W2001489087 creator A5028498042 @default.
- W2001489087 creator A5031837957 @default.
- W2001489087 creator A5061167008 @default.
- W2001489087 creator A5082392576 @default.
- W2001489087 date "2007-04-01" @default.
- W2001489087 modified "2023-10-07" @default.
- W2001489087 title "Monoclonal Gammopathy of Undetermined Significance: Predictors of Malignant Transformation and Recognition of an Evolving Type Characterized by a Progressive Increase in M Protein Size" @default.
- W2001489087 cites W1509074607 @default.
- W2001489087 cites W1969732814 @default.
- W2001489087 cites W2002927100 @default.
- W2001489087 cites W2050004237 @default.
- W2001489087 cites W2075092656 @default.
- W2001489087 cites W2086990334 @default.
- W2001489087 cites W2090476338 @default.
- W2001489087 cites W2105790938 @default.
- W2001489087 cites W2119707919 @default.
- W2001489087 cites W2128036931 @default.
- W2001489087 cites W2606199847 @default.
- W2001489087 cites W4293241248 @default.
- W2001489087 cites W4298434897 @default.
- W2001489087 cites W3143387670 @default.
- W2001489087 doi "https://doi.org/10.4065/82.4.428" @default.
- W2001489087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17418070" @default.
- W2001489087 hasPublicationYear "2007" @default.
- W2001489087 type Work @default.
- W2001489087 sameAs 2001489087 @default.
- W2001489087 citedByCount "81" @default.
- W2001489087 countsByYear W20014890872012 @default.
- W2001489087 countsByYear W20014890872013 @default.
- W2001489087 countsByYear W20014890872014 @default.
- W2001489087 countsByYear W20014890872015 @default.
- W2001489087 countsByYear W20014890872016 @default.
- W2001489087 countsByYear W20014890872017 @default.
- W2001489087 countsByYear W20014890872018 @default.
- W2001489087 countsByYear W20014890872019 @default.
- W2001489087 countsByYear W20014890872020 @default.
- W2001489087 countsByYear W20014890872021 @default.
- W2001489087 countsByYear W20014890872022 @default.
- W2001489087 countsByYear W20014890872023 @default.
- W2001489087 crossrefType "journal-article" @default.
- W2001489087 hasAuthorship W2001489087A5008706897 @default.
- W2001489087 hasAuthorship W2001489087A5015898454 @default.
- W2001489087 hasAuthorship W2001489087A5017225753 @default.
- W2001489087 hasAuthorship W2001489087A5028498042 @default.
- W2001489087 hasAuthorship W2001489087A5031837957 @default.
- W2001489087 hasAuthorship W2001489087A5061167008 @default.
- W2001489087 hasAuthorship W2001489087A5082392576 @default.
- W2001489087 hasConcept C126322002 @default.
- W2001489087 hasConcept C142724271 @default.
- W2001489087 hasConcept C159654299 @default.
- W2001489087 hasConcept C163864487 @default.
- W2001489087 hasConcept C203014093 @default.
- W2001489087 hasConcept C2777250017 @default.
- W2001489087 hasConcept C2778112473 @default.
- W2001489087 hasConcept C31033888 @default.
- W2001489087 hasConcept C44249647 @default.
- W2001489087 hasConcept C542903549 @default.
- W2001489087 hasConcept C71924100 @default.
- W2001489087 hasConcept C82789193 @default.
- W2001489087 hasConcept C90924648 @default.
- W2001489087 hasConceptScore W2001489087C126322002 @default.
- W2001489087 hasConceptScore W2001489087C142724271 @default.
- W2001489087 hasConceptScore W2001489087C159654299 @default.
- W2001489087 hasConceptScore W2001489087C163864487 @default.
- W2001489087 hasConceptScore W2001489087C203014093 @default.
- W2001489087 hasConceptScore W2001489087C2777250017 @default.
- W2001489087 hasConceptScore W2001489087C2778112473 @default.
- W2001489087 hasConceptScore W2001489087C31033888 @default.
- W2001489087 hasConceptScore W2001489087C44249647 @default.
- W2001489087 hasConceptScore W2001489087C542903549 @default.
- W2001489087 hasConceptScore W2001489087C71924100 @default.
- W2001489087 hasConceptScore W2001489087C82789193 @default.
- W2001489087 hasConceptScore W2001489087C90924648 @default.
- W2001489087 hasIssue "4" @default.
- W2001489087 hasLocation W20014890871 @default.
- W2001489087 hasLocation W20014890872 @default.
- W2001489087 hasOpenAccess W2001489087 @default.
- W2001489087 hasPrimaryLocation W20014890871 @default.
- W2001489087 hasRelatedWork W1994697757 @default.
- W2001489087 hasRelatedWork W2001489087 @default.
- W2001489087 hasRelatedWork W2030866971 @default.
- W2001489087 hasRelatedWork W2333967111 @default.
- W2001489087 hasRelatedWork W2743580733 @default.
- W2001489087 hasRelatedWork W2982027572 @default.
- W2001489087 hasRelatedWork W3164663668 @default.
- W2001489087 hasRelatedWork W4214528822 @default.
- W2001489087 hasRelatedWork W4240507495 @default.
- W2001489087 hasRelatedWork W4247794702 @default.
- W2001489087 hasVolume "82" @default.
- W2001489087 isParatext "false" @default.
- W2001489087 isRetracted "false" @default.
- W2001489087 magId "2001489087" @default.
- W2001489087 workType "article" @default.