Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001502893> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2001502893 endingPage "126" @default.
- W2001502893 startingPage "117" @default.
- W2001502893 abstract "This heparin affinity chromatography study revealed some very interesting aspects with respect to oligopeptide retention. The first and most surprising effect observed was that oligopeptides with no aromatic groups were not retained on the column while those with aromatic groups were retained. The aromatic interaction was determined to be related to a charge transfer -like interaction as electron donating groups on the aromatic moiety increased retention on the column and electron withdrawing groups on the aromatic moiety deceased retention time. Column retention was dependent on oligopeptide size; the tripeptides were not retained while tetrapeptides and the larger hexapeptides were effectively retained if they contained some aromatic functionality. Retention was pH dependent; low pH's of ∼2.5 were most effective while neutral pH was not effective in retaining the oligopeptides on the heparin affinity column. In addition to the aromatic interaction, retention was dependent on the hydrophobicity of the oligopeptides as well as their ability to hydrogen bond as determined by eluent solvent effects on the heparin affinity column. These results have led us design and carry out other experiments to determine more accurately the type and the degree of oligopeptide to heparin interaction." @default.
- W2001502893 created "2016-06-24" @default.
- W2001502893 creator A5003966176 @default.
- W2001502893 creator A5008636987 @default.
- W2001502893 creator A5045078374 @default.
- W2001502893 date "2001-10-01" @default.
- W2001502893 modified "2023-09-23" @default.
- W2001502893 title "Interaction of oligopeptides with heparin" @default.
- W2001502893 cites W1527005256 @default.
- W2001502893 cites W1848741139 @default.
- W2001502893 cites W1979718617 @default.
- W2001502893 cites W2001853501 @default.
- W2001502893 cites W2013112400 @default.
- W2001502893 cites W2038042309 @default.
- W2001502893 cites W2069911400 @default.
- W2001502893 cites W2074924352 @default.
- W2001502893 cites W2083859586 @default.
- W2001502893 cites W2129786019 @default.
- W2001502893 cites W2139741471 @default.
- W2001502893 cites W2318108904 @default.
- W2001502893 cites W2950367394 @default.
- W2001502893 cites W622829001 @default.
- W2001502893 cites W65759580 @default.
- W2001502893 cites W86636539 @default.
- W2001502893 doi "https://doi.org/10.1002/1521-3900(200110)175:1<117::aid-masy117>3.0.co;2-0" @default.
- W2001502893 hasPublicationYear "2001" @default.
- W2001502893 type Work @default.
- W2001502893 sameAs 2001502893 @default.
- W2001502893 citedByCount "2" @default.
- W2001502893 crossrefType "journal-article" @default.
- W2001502893 hasAuthorship W2001502893A5003966176 @default.
- W2001502893 hasAuthorship W2001502893A5008636987 @default.
- W2001502893 hasAuthorship W2001502893A5045078374 @default.
- W2001502893 hasConcept C13935069 @default.
- W2001502893 hasConcept C167392928 @default.
- W2001502893 hasConcept C178790620 @default.
- W2001502893 hasConcept C185592680 @default.
- W2001502893 hasConcept C192386470 @default.
- W2001502893 hasConcept C2776568683 @default.
- W2001502893 hasConcept C2779281246 @default.
- W2001502893 hasConcept C32909587 @default.
- W2001502893 hasConcept C43617362 @default.
- W2001502893 hasConcept C51724486 @default.
- W2001502893 hasConcept C55493867 @default.
- W2001502893 hasConcept C71240020 @default.
- W2001502893 hasConcept C90260826 @default.
- W2001502893 hasConceptScore W2001502893C13935069 @default.
- W2001502893 hasConceptScore W2001502893C167392928 @default.
- W2001502893 hasConceptScore W2001502893C178790620 @default.
- W2001502893 hasConceptScore W2001502893C185592680 @default.
- W2001502893 hasConceptScore W2001502893C192386470 @default.
- W2001502893 hasConceptScore W2001502893C2776568683 @default.
- W2001502893 hasConceptScore W2001502893C2779281246 @default.
- W2001502893 hasConceptScore W2001502893C32909587 @default.
- W2001502893 hasConceptScore W2001502893C43617362 @default.
- W2001502893 hasConceptScore W2001502893C51724486 @default.
- W2001502893 hasConceptScore W2001502893C55493867 @default.
- W2001502893 hasConceptScore W2001502893C71240020 @default.
- W2001502893 hasConceptScore W2001502893C90260826 @default.
- W2001502893 hasIssue "1" @default.
- W2001502893 hasLocation W20015028931 @default.
- W2001502893 hasOpenAccess W2001502893 @default.
- W2001502893 hasPrimaryLocation W20015028931 @default.
- W2001502893 hasRelatedWork W13708140 @default.
- W2001502893 hasRelatedWork W1509164559 @default.
- W2001502893 hasRelatedWork W1994086798 @default.
- W2001502893 hasRelatedWork W2001502893 @default.
- W2001502893 hasRelatedWork W2038462421 @default.
- W2001502893 hasRelatedWork W2049485506 @default.
- W2001502893 hasRelatedWork W2078606007 @default.
- W2001502893 hasRelatedWork W2086058048 @default.
- W2001502893 hasRelatedWork W2161084168 @default.
- W2001502893 hasRelatedWork W2793175862 @default.
- W2001502893 hasVolume "175" @default.
- W2001502893 isParatext "false" @default.
- W2001502893 isRetracted "false" @default.
- W2001502893 magId "2001502893" @default.
- W2001502893 workType "article" @default.