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• W2001544511 abstract "Dengue virus infection causes diseases in people, ranging from the acute febrile illness dengue fever, to life-threatening dengue hemorrhagic fever/dengue shock syndrome. We previously reported that a host cellular α-glucosidases I and II inhibitor, imino sugar CM-10–18, potently inhibited dengue virus replication in cultured cells, and significantly reduced viremia in dengue virus infected AG129 mice. In this report we show that CM-10–18 also significantly protects mice from death and/or disease progress in two mouse models of lethal dengue virus infection. Our results thus provide a strong support for the development of CM-10–18 or its derivatives as antiviral agents to treat servere dengue virus infections." @default.
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• W2001544511 date "2011-11-01" @default.
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• W2001544511 title "Competitive inhibitor of cellular α-glucosidases protects mice from lethal dengue virus infection" @default.
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• W2001544511 doi "https://doi.org/10.1016/j.antiviral.2011.08.003" @default.
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