Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001565072> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2001565072 endingPage "258" @default.
- W2001565072 startingPage "254" @default.
- W2001565072 abstract "Cerebral ischemia is known to modify the expression of genetic information in the brain. To complement this knowledge, in the present study we have estimated the expression of calcium- and phospholipid-dependent (classical) protein kinase C (c PKC) isoform mRNAs (α, βI and γ) at different time following ischemia. Forebrain cerebral ischemia was performed on Mongolian gerbils by 5 minutes bilateral occlusion of common carotid arteries. At the pointed time the cytoplasmic RNA was extracted from hippocampus and the expression of PKC mRNA quantified by RT PCR technique using GAPDH expression as an internal standard. Results indicate that only one γ isoform of cPKC mRNA expression becomes significantly modified in postischemic hippocampus. A transient increase up to 145% of control within the first 3 h was followed by its decline to 60–65% at a longer recirculation period. This lowered levels returned back to control at 72 h postischemic recovery. This result indicates that γ PKC could be particularly sensitive to ischemic insult and would react in accordance with the other early signals determining ischemic outcome." @default.
- W2001565072 created "2016-06-24" @default.
- W2001565072 creator A5003692369 @default.
- W2001565072 creator A5030626364 @default.
- W2001565072 creator A5051938025 @default.
- W2001565072 creator A5068427427 @default.
- W2001565072 date "1998-01-01" @default.
- W2001565072 modified "2023-10-18" @default.
- W2001565072 title "Expression of Ca2+-dependent (classical) PKC mRNA isoforms after transient cerebral ischemia in gerbil hippocampus" @default.
- W2001565072 cites W1969990740 @default.
- W2001565072 cites W1974844063 @default.
- W2001565072 cites W1988475591 @default.
- W2001565072 cites W1989040173 @default.
- W2001565072 cites W1993608966 @default.
- W2001565072 cites W1996337563 @default.
- W2001565072 cites W2022342758 @default.
- W2001565072 cites W2030035797 @default.
- W2001565072 cites W2036979250 @default.
- W2001565072 cites W2040113888 @default.
- W2001565072 cites W2042569804 @default.
- W2001565072 cites W2076135710 @default.
- W2001565072 cites W2088527212 @default.
- W2001565072 cites W2089104876 @default.
- W2001565072 cites W2104238984 @default.
- W2001565072 cites W2113306289 @default.
- W2001565072 doi "https://doi.org/10.1016/s0006-8993(97)00906-2" @default.
- W2001565072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9473687" @default.
- W2001565072 hasPublicationYear "1998" @default.
- W2001565072 type Work @default.
- W2001565072 sameAs 2001565072 @default.
- W2001565072 citedByCount "15" @default.
- W2001565072 countsByYear W20015650722014 @default.
- W2001565072 countsByYear W20015650722023 @default.
- W2001565072 crossrefType "journal-article" @default.
- W2001565072 hasAuthorship W2001565072A5003692369 @default.
- W2001565072 hasAuthorship W2001565072A5030626364 @default.
- W2001565072 hasAuthorship W2001565072A5051938025 @default.
- W2001565072 hasAuthorship W2001565072A5068427427 @default.
- W2001565072 hasConcept C104317684 @default.
- W2001565072 hasConcept C105580179 @default.
- W2001565072 hasConcept C126322002 @default.
- W2001565072 hasConcept C134018914 @default.
- W2001565072 hasConcept C169760540 @default.
- W2001565072 hasConcept C184235292 @default.
- W2001565072 hasConcept C195794163 @default.
- W2001565072 hasConcept C2780222073 @default.
- W2001565072 hasConcept C2781161787 @default.
- W2001565072 hasConcept C53345823 @default.
- W2001565072 hasConcept C541997718 @default.
- W2001565072 hasConcept C55493867 @default.
- W2001565072 hasConcept C71924100 @default.
- W2001565072 hasConcept C86803240 @default.
- W2001565072 hasConcept C95444343 @default.
- W2001565072 hasConceptScore W2001565072C104317684 @default.
- W2001565072 hasConceptScore W2001565072C105580179 @default.
- W2001565072 hasConceptScore W2001565072C126322002 @default.
- W2001565072 hasConceptScore W2001565072C134018914 @default.
- W2001565072 hasConceptScore W2001565072C169760540 @default.
- W2001565072 hasConceptScore W2001565072C184235292 @default.
- W2001565072 hasConceptScore W2001565072C195794163 @default.
- W2001565072 hasConceptScore W2001565072C2780222073 @default.
- W2001565072 hasConceptScore W2001565072C2781161787 @default.
- W2001565072 hasConceptScore W2001565072C53345823 @default.
- W2001565072 hasConceptScore W2001565072C541997718 @default.
- W2001565072 hasConceptScore W2001565072C55493867 @default.
- W2001565072 hasConceptScore W2001565072C71924100 @default.
- W2001565072 hasConceptScore W2001565072C86803240 @default.
- W2001565072 hasConceptScore W2001565072C95444343 @default.
- W2001565072 hasIssue "1-2" @default.
- W2001565072 hasLocation W20015650721 @default.
- W2001565072 hasLocation W20015650722 @default.
- W2001565072 hasOpenAccess W2001565072 @default.
- W2001565072 hasPrimaryLocation W20015650721 @default.
- W2001565072 hasRelatedWork W1986328616 @default.
- W2001565072 hasRelatedWork W2013363962 @default.
- W2001565072 hasRelatedWork W2031543068 @default.
- W2001565072 hasRelatedWork W2038909506 @default.
- W2001565072 hasRelatedWork W2061706623 @default.
- W2001565072 hasRelatedWork W2079000568 @default.
- W2001565072 hasRelatedWork W2084171971 @default.
- W2001565072 hasRelatedWork W2115351128 @default.
- W2001565072 hasRelatedWork W2143053194 @default.
- W2001565072 hasRelatedWork W2414235747 @default.
- W2001565072 hasVolume "779" @default.
- W2001565072 isParatext "false" @default.
- W2001565072 isRetracted "false" @default.
- W2001565072 magId "2001565072" @default.
- W2001565072 workType "article" @default.