Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001603363> ?p ?o ?g. }
- W2001603363 endingPage "511" @default.
- W2001603363 startingPage "501" @default.
- W2001603363 abstract "It is now widely accepted that the mammary gland is under interconnected hormonal and local control. Growth factors are involved in the intercellular signalling of the gland. Our aim was the detection of transforming growth factors alpha (TGF-alpha) and beta 1 (TGF-beta 1) messenger RNA during mammogenesis, lactogenesis, galactopoiesis and involution in the bovine mammary gland (total n = 27). During these stages the RNA was assessed by means of ribonuclease protection assay and reverse transcription-polymerase chain reaction (RT-PCR). To study possible influences of oestrogen, progesterone and prolactin on growth factor expression, mammary RNA was obtained from heifers after induced mammogenesis and lactogenesis, with and without additional prolactin inhibition (total n = 20). Very low levels of TGF-alpha and TGF-beta 1 expression were detected during lactogenesis and galactopoiesis, increasing levels during mammogenesis of primigravid heifers, and highest levels during mammogenesis of virgin heifers and during involution. TGF-alpha expression after induced mammogenesis was greater than after induced lactogenesis or physiological mammogenesis during pregnancy. Furthermore, TGF-alpha mRNA contents increased after prolactin inhibition. TGF-beta 1 expression was almost equal after induced mammogenesis and lactogenesis, but greater than during the physiological mammogenesis and lactogenesis. In conclusion, it can be assumed that growth promoting TGF-alpha and growth inhibiting TGF-beta 1 are co-expressed in the bovine mammary gland. Higher mRNA contents of both factors during mammogenesis and involution may indicate autocrine or paracrine functions for these growth factors during proliferation and reorganisation of the mammary tissue." @default.
- W2001603363 created "2016-06-24" @default.
- W2001603363 creator A5020818672 @default.
- W2001603363 creator A5021567331 @default.
- W2001603363 creator A5061451542 @default.
- W2001603363 creator A5076738851 @default.
- W2001603363 creator A5088672675 @default.
- W2001603363 date "1997-12-01" @default.
- W2001603363 modified "2023-10-10" @default.
- W2001603363 title "Expression of transforming growth factors alpha and beta-1 messenger RNA in the bovine mammary gland during different stages of development and lactation" @default.
- W2001603363 cites W1561326647 @default.
- W2001603363 cites W1568217878 @default.
- W2001603363 cites W1579214734 @default.
- W2001603363 cites W1969793246 @default.
- W2001603363 cites W1972463403 @default.
- W2001603363 cites W1975514265 @default.
- W2001603363 cites W1975521980 @default.
- W2001603363 cites W1981692609 @default.
- W2001603363 cites W1988372557 @default.
- W2001603363 cites W1990351263 @default.
- W2001603363 cites W1991975603 @default.
- W2001603363 cites W1998954931 @default.
- W2001603363 cites W2008535160 @default.
- W2001603363 cites W2012309658 @default.
- W2001603363 cites W2019647633 @default.
- W2001603363 cites W2020533397 @default.
- W2001603363 cites W2024507604 @default.
- W2001603363 cites W2030030611 @default.
- W2001603363 cites W2032525309 @default.
- W2001603363 cites W2039202948 @default.
- W2001603363 cites W2041310029 @default.
- W2001603363 cites W2046754369 @default.
- W2001603363 cites W2057604085 @default.
- W2001603363 cites W2065418754 @default.
- W2001603363 cites W2069602882 @default.
- W2001603363 cites W2070371957 @default.
- W2001603363 cites W2073865988 @default.
- W2001603363 cites W2082405573 @default.
- W2001603363 cites W2082677148 @default.
- W2001603363 cites W2085899645 @default.
- W2001603363 cites W2091616139 @default.
- W2001603363 cites W2134812217 @default.
- W2001603363 cites W2139839934 @default.
- W2001603363 cites W2141276395 @default.
- W2001603363 cites W2170643587 @default.
- W2001603363 cites W2279922459 @default.
- W2001603363 cites W2395606352 @default.
- W2001603363 cites W2409685048 @default.
- W2001603363 cites W2435401184 @default.
- W2001603363 cites W2463704589 @default.
- W2001603363 cites W3023110197 @default.
- W2001603363 doi "https://doi.org/10.1677/joe.0.1550501" @default.
- W2001603363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9487995" @default.
- W2001603363 hasPublicationYear "1997" @default.
- W2001603363 type Work @default.
- W2001603363 sameAs 2001603363 @default.
- W2001603363 citedByCount "66" @default.
- W2001603363 countsByYear W20016033632012 @default.
- W2001603363 countsByYear W20016033632013 @default.
- W2001603363 countsByYear W20016033632014 @default.
- W2001603363 countsByYear W20016033632016 @default.
- W2001603363 countsByYear W20016033632018 @default.
- W2001603363 countsByYear W20016033632019 @default.
- W2001603363 countsByYear W20016033632020 @default.
- W2001603363 countsByYear W20016033632021 @default.
- W2001603363 countsByYear W20016033632022 @default.
- W2001603363 countsByYear W20016033632023 @default.
- W2001603363 crossrefType "journal-article" @default.
- W2001603363 hasAuthorship W2001603363A5020818672 @default.
- W2001603363 hasAuthorship W2001603363A5021567331 @default.
- W2001603363 hasAuthorship W2001603363A5061451542 @default.
- W2001603363 hasAuthorship W2001603363A5076738851 @default.
- W2001603363 hasAuthorship W2001603363A5088672675 @default.
- W2001603363 hasConcept C104317684 @default.
- W2001603363 hasConcept C105580179 @default.
- W2001603363 hasConcept C118131993 @default.
- W2001603363 hasConcept C121608353 @default.
- W2001603363 hasConcept C126322002 @default.
- W2001603363 hasConcept C128240485 @default.
- W2001603363 hasConcept C134018914 @default.
- W2001603363 hasConcept C169760540 @default.
- W2001603363 hasConcept C170493617 @default.
- W2001603363 hasConcept C177752829 @default.
- W2001603363 hasConcept C186720457 @default.
- W2001603363 hasConcept C2776659692 @default.
- W2001603363 hasConcept C2778001805 @default.
- W2001603363 hasConcept C2779064019 @default.
- W2001603363 hasConcept C2779234561 @default.
- W2001603363 hasConcept C2781409172 @default.
- W2001603363 hasConcept C2984496839 @default.
- W2001603363 hasConcept C530470458 @default.
- W2001603363 hasConcept C54355233 @default.
- W2001603363 hasConcept C55493867 @default.
- W2001603363 hasConcept C67705224 @default.
- W2001603363 hasConcept C71315377 @default.
- W2001603363 hasConcept C71924100 @default.
- W2001603363 hasConcept C7876069 @default.
- W2001603363 hasConcept C86803240 @default.