Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001654037> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2001654037 endingPage "19" @default.
- W2001654037 startingPage "19" @default.
- W2001654037 abstract "Purpose The optimal chemotherapeutic strategy for gastric cancer patients has not been determined, especially with respect to stage and the curability of gastric cancer. The aim of this study was to evaluate the results of adjuvant chemotherapy on stage IV (T4N1-3M0 and T1-3N3M0) gastric cancer after curative gastrectomy between a chemotherapy (CTX) group and non-chemotherapy (non-CTX) group. Materials and Methods Among 1,760 patients who underwent gastric surgery by 1 surgeon in a single institution, 162 stage IV gastric cancer patients with curative gastrectomy were analyzed retrospectively, excluding patients with TanyNanyM1. One hundred twenty-five patients who received different chemotherapeutic regimens were compared to 37 patients who did not receive chemotherapy for reasons of old age or according to their expressed desire. Results The clinicopathologic factors which showed a clinically significant difference between the two groups were age and histology, which were not associated with patient survival. The CTX group was younger, and had a larger proportion of undifferentiated gastric cancers than the non-CTX group. The mode of treatment failure revealed no significant difference between the CTX and non-CTX groups. The 1, 3, and 5-year disease-free survival and the 1, 3, and 5-year disease-specific survival of the CTX group were 63.9%, 38.4%, and 32.0%, and 85.4%, 52.3%, and 39.6%, respectively, which were more favorable than the non-CTX group (p=0.015 and p=0.001, respectively). Postoperative adjuvant CTX was an independent risk factor for disease-specific survival of stage IV (T4N1-3M0 and T1-3N3M0) gastric cancer patients after curative gastrectomy by multivariate analysis (odds ratio=2.153; 95% confidence interval=1.349-3.435; p=0.001). Conclusions Adjuvant CTX may be associated with survival benefit for younger patients with stage IV (T4N1-3M0 and T1-3N3M0) gastric cancer with undifferentiated histology after curative gastrectomy. A randomized controlled trial to reveal the effect of stage-specific adjuvant chemotherapy should be conducted. Key words: Adjuvant chemotherapy, Stage IV gastric cancer, Curative gastrectomy, survival" @default.
- W2001654037 created "2016-06-24" @default.
- W2001654037 creator A5023805615 @default.
- W2001654037 creator A5053553524 @default.
- W2001654037 creator A5055143444 @default.
- W2001654037 creator A5081821112 @default.
- W2001654037 creator A5085703687 @default.
- W2001654037 date "2009-01-01" @default.
- W2001654037 modified "2023-09-24" @default.
- W2001654037 title "The Effect of Adjuvant Chemotherapy on Stage IV (T4N1-3M0 and T1-3N3M0) Gastric Cancer" @default.
- W2001654037 cites W1748728040 @default.
- W2001654037 cites W1973992335 @default.
- W2001654037 cites W1976067349 @default.
- W2001654037 cites W2000513683 @default.
- W2001654037 cites W2005046276 @default.
- W2001654037 cites W2026986976 @default.
- W2001654037 cites W2034928508 @default.
- W2001654037 cites W2065887320 @default.
- W2001654037 cites W2076668534 @default.
- W2001654037 cites W2095373976 @default.
- W2001654037 cites W2106474180 @default.
- W2001654037 cites W2115072149 @default.
- W2001654037 cites W2131757526 @default.
- W2001654037 cites W2137991416 @default.
- W2001654037 cites W2141768150 @default.
- W2001654037 cites W2154773141 @default.
- W2001654037 cites W2162746289 @default.
- W2001654037 cites W2163912927 @default.
- W2001654037 cites W2395101107 @default.
- W2001654037 cites W4238602544 @default.
- W2001654037 cites W4255483444 @default.
- W2001654037 cites W80011325 @default.
- W2001654037 doi "https://doi.org/10.4143/crt.2009.41.1.19" @default.
- W2001654037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2699090" @default.
- W2001654037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19688067" @default.
- W2001654037 hasPublicationYear "2009" @default.
- W2001654037 type Work @default.
- W2001654037 sameAs 2001654037 @default.
- W2001654037 citedByCount "2" @default.
- W2001654037 countsByYear W20016540372014 @default.
- W2001654037 countsByYear W20016540372018 @default.
- W2001654037 crossrefType "journal-article" @default.
- W2001654037 hasAuthorship W2001654037A5023805615 @default.
- W2001654037 hasAuthorship W2001654037A5053553524 @default.
- W2001654037 hasAuthorship W2001654037A5055143444 @default.
- W2001654037 hasAuthorship W2001654037A5081821112 @default.
- W2001654037 hasAuthorship W2001654037A5085703687 @default.
- W2001654037 hasBestOaLocation W20016540371 @default.
- W2001654037 hasConcept C121608353 @default.
- W2001654037 hasConcept C126322002 @default.
- W2001654037 hasConcept C141071460 @default.
- W2001654037 hasConcept C143998085 @default.
- W2001654037 hasConcept C146357865 @default.
- W2001654037 hasConcept C151730666 @default.
- W2001654037 hasConcept C2776694085 @default.
- W2001654037 hasConcept C2777863537 @default.
- W2001654037 hasConcept C2780470880 @default.
- W2001654037 hasConcept C71924100 @default.
- W2001654037 hasConcept C86803240 @default.
- W2001654037 hasConcept C90924648 @default.
- W2001654037 hasConceptScore W2001654037C121608353 @default.
- W2001654037 hasConceptScore W2001654037C126322002 @default.
- W2001654037 hasConceptScore W2001654037C141071460 @default.
- W2001654037 hasConceptScore W2001654037C143998085 @default.
- W2001654037 hasConceptScore W2001654037C146357865 @default.
- W2001654037 hasConceptScore W2001654037C151730666 @default.
- W2001654037 hasConceptScore W2001654037C2776694085 @default.
- W2001654037 hasConceptScore W2001654037C2777863537 @default.
- W2001654037 hasConceptScore W2001654037C2780470880 @default.
- W2001654037 hasConceptScore W2001654037C71924100 @default.
- W2001654037 hasConceptScore W2001654037C86803240 @default.
- W2001654037 hasConceptScore W2001654037C90924648 @default.
- W2001654037 hasIssue "1" @default.
- W2001654037 hasLocation W20016540371 @default.
- W2001654037 hasLocation W20016540372 @default.
- W2001654037 hasLocation W20016540373 @default.
- W2001654037 hasLocation W20016540374 @default.
- W2001654037 hasOpenAccess W2001654037 @default.
- W2001654037 hasPrimaryLocation W20016540371 @default.
- W2001654037 hasRelatedWork W167319750 @default.
- W2001654037 hasRelatedWork W1987468340 @default.
- W2001654037 hasRelatedWork W2022421062 @default.
- W2001654037 hasRelatedWork W2035238600 @default.
- W2001654037 hasRelatedWork W2362580737 @default.
- W2001654037 hasRelatedWork W2412448412 @default.
- W2001654037 hasRelatedWork W2415186990 @default.
- W2001654037 hasRelatedWork W2419344967 @default.
- W2001654037 hasRelatedWork W2471255862 @default.
- W2001654037 hasRelatedWork W3029632585 @default.
- W2001654037 hasVolume "41" @default.
- W2001654037 isParatext "false" @default.
- W2001654037 isRetracted "false" @default.
- W2001654037 magId "2001654037" @default.
- W2001654037 workType "article" @default.