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- W2001658913 abstract "Vitamin E is an important nutrient with antioxidant and non-antioxidant functions, and certain evidence suggests that it has a cardiovascular protective role. It is therefore important to maintain an optimal vitamin E status. In the present paper, a number of MS applications to monitor vitamin E status and its interactions, including the use of stable-isotope-labelled vitamin E and metabonomics, are highlighted. Specifically, stable-isotope studies have been used to monitor vitamin E absorption, hepatic processing and lipoprotein transport. As oxidative stress may influence vitamin E status, a number of studies comparing vitamin E biokinetics and metabolism in cigarette smokers and non-smokers have been able to show differences in vitamin E processing in smokers. Metabonomics represents a method to identify changes to metabolite profiles, offering the potential to investigate interactions between vitamin E and metabolic pathways. These applications represent innovative approaches to investigate the role of vitamin E in health and disease." @default.
- W2001658913 created "2016-06-24" @default.
- W2001658913 creator A5045873156 @default.
- W2001658913 date "2008-09-19" @default.
- W2001658913 modified "2023-09-29" @default.
- W2001658913 title "Mass spectrometry approaches for vitamin E research" @default.
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- W2001658913 doi "https://doi.org/10.1042/bst0361066" @default.
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