Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001682021> ?p ?o ?g. }
- W2001682021 endingPage "337" @default.
- W2001682021 startingPage "331" @default.
- W2001682021 abstract "Bilateral olfactory bulbectomy (OBX) in rats produces a well-characterized syndrome of behavioral, physiological, and neurochemical changes identical to those seen in depression. Previous experiments using in situ hybridization histochemistry have demonstrated that OBX increases prepro-neuropeptide-Y (NPY) and prepro-enkephalin (ENK) mRNA levels in limbic structures. The present experiments determined whether increases in peptide immunoreactivity occur in conjunction with increases in mRNA levels following OBX. In situ hybridization analyses in olfactory bulbectomized and sham-operated rats revealed increased prepro-ENK mRNA in the piriform cortex (PIR) and olfactory tubercles (OTs) of bulbectomized rats. Prepro-NPY mRNA levels were significantly increased in the PIR of bulbectomized rats as comapred to controls. Radioimmunoassays (RIAs) revealed significant elevations in ENK-like immunoreactivity in the OTs following OBX. NPY-like immunoreactivity was significantly elevated in the PIR following OBX. These data reveal that OBX-induced increases in ENK-like immunoreactivity occur concomitantly with increases in prepro-ENK mRNA, and NPY-like immunoreactivity occur concomitantly with increases in prepro-NPY mRNA." @default.
- W2001682021 created "2016-06-24" @default.
- W2001682021 creator A5031474690 @default.
- W2001682021 creator A5042979738 @default.
- W2001682021 date "2000-10-01" @default.
- W2001682021 modified "2023-09-27" @default.
- W2001682021 title "Olfactory bulbectomy increases met-enkephalin- and neuropeptide-Y-like immunoreactivity in rat limbic structures" @default.
- W2001682021 cites W1529166175 @default.
- W2001682021 cites W1652867881 @default.
- W2001682021 cites W1792087787 @default.
- W2001682021 cites W18083684 @default.
- W2001682021 cites W1965454331 @default.
- W2001682021 cites W1966464425 @default.
- W2001682021 cites W1968277908 @default.
- W2001682021 cites W1969462305 @default.
- W2001682021 cites W1972632161 @default.
- W2001682021 cites W1974934764 @default.
- W2001682021 cites W1978573386 @default.
- W2001682021 cites W1981543063 @default.
- W2001682021 cites W1986346002 @default.
- W2001682021 cites W1987294827 @default.
- W2001682021 cites W1989446622 @default.
- W2001682021 cites W1989972486 @default.
- W2001682021 cites W1991603311 @default.
- W2001682021 cites W1992784996 @default.
- W2001682021 cites W1993064970 @default.
- W2001682021 cites W1995181975 @default.
- W2001682021 cites W1995257658 @default.
- W2001682021 cites W1997304565 @default.
- W2001682021 cites W1997689548 @default.
- W2001682021 cites W2014989557 @default.
- W2001682021 cites W2022168313 @default.
- W2001682021 cites W2031872534 @default.
- W2001682021 cites W2034710100 @default.
- W2001682021 cites W2035911533 @default.
- W2001682021 cites W2037001022 @default.
- W2001682021 cites W2047251449 @default.
- W2001682021 cites W2048258555 @default.
- W2001682021 cites W2049201330 @default.
- W2001682021 cites W2050962637 @default.
- W2001682021 cites W2052970369 @default.
- W2001682021 cites W2057176173 @default.
- W2001682021 cites W2057994478 @default.
- W2001682021 cites W2058638925 @default.
- W2001682021 cites W2061281984 @default.
- W2001682021 cites W2066442135 @default.
- W2001682021 cites W2073206419 @default.
- W2001682021 cites W2077029309 @default.
- W2001682021 cites W2078802300 @default.
- W2001682021 cites W2081313201 @default.
- W2001682021 cites W2082683656 @default.
- W2001682021 cites W2084642269 @default.
- W2001682021 cites W2097919380 @default.
- W2001682021 cites W2102864876 @default.
- W2001682021 cites W2110629635 @default.
- W2001682021 cites W2114207789 @default.
- W2001682021 cites W4234193719 @default.
- W2001682021 doi "https://doi.org/10.1016/s0091-3057(00)00358-0" @default.
- W2001682021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11124398" @default.
- W2001682021 hasPublicationYear "2000" @default.
- W2001682021 type Work @default.
- W2001682021 sameAs 2001682021 @default.
- W2001682021 citedByCount "27" @default.
- W2001682021 countsByYear W20016820212012 @default.
- W2001682021 countsByYear W20016820212014 @default.
- W2001682021 countsByYear W20016820212015 @default.
- W2001682021 countsByYear W20016820212018 @default.
- W2001682021 countsByYear W20016820212019 @default.
- W2001682021 countsByYear W20016820212021 @default.
- W2001682021 crossrefType "journal-article" @default.
- W2001682021 hasAuthorship W2001682021A5031474690 @default.
- W2001682021 hasAuthorship W2001682021A5042979738 @default.
- W2001682021 hasConcept C104317684 @default.
- W2001682021 hasConcept C105580179 @default.
- W2001682021 hasConcept C118303440 @default.
- W2001682021 hasConcept C126322002 @default.
- W2001682021 hasConcept C134018914 @default.
- W2001682021 hasConcept C169760540 @default.
- W2001682021 hasConcept C170493617 @default.
- W2001682021 hasConcept C176685330 @default.
- W2001682021 hasConcept C201792869 @default.
- W2001682021 hasConcept C25876315 @default.
- W2001682021 hasConcept C2777803847 @default.
- W2001682021 hasConcept C2780382662 @default.
- W2001682021 hasConcept C2780496858 @default.
- W2001682021 hasConcept C2781063702 @default.
- W2001682021 hasConcept C529278444 @default.
- W2001682021 hasConcept C55493867 @default.
- W2001682021 hasConcept C71924100 @default.
- W2001682021 hasConcept C81439078 @default.
- W2001682021 hasConcept C86803240 @default.
- W2001682021 hasConcept C93984277 @default.
- W2001682021 hasConceptScore W2001682021C104317684 @default.
- W2001682021 hasConceptScore W2001682021C105580179 @default.
- W2001682021 hasConceptScore W2001682021C118303440 @default.
- W2001682021 hasConceptScore W2001682021C126322002 @default.
- W2001682021 hasConceptScore W2001682021C134018914 @default.
- W2001682021 hasConceptScore W2001682021C169760540 @default.