FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001736286> ?p ?o ?g. }

• W2001736286 endingPage "97" @default.
• W2001736286 startingPage "88" @default.
• W2001736286 abstract "Nodular goiter is present in 500 to 600 million people and is usually secondary to endemic iodine deficiency. Despite adequate iodine intake, 4% to 6% of American adults are goitrous. Sporadic nodular goiter ensues from the natural heterogeneity of thyroid follicular cells, which, when amplified by yet unidentified trophic stimuli, results in episodes of proliferating, rapidly dividing micronodules. The initial small diffuse goiter evolves into a multinodular goiter (MNG) with 1 or more dominant nodules that may or may not be autonomous. An autonomous functioning thyroid adenoma (AFTA) usually possesses a somatic gain-of-function mutation of the thyrotropin (TSH) receptor associated with rapid growth, hemorrhagic necrosis, and reparative fibrosis that accentuate goiter nodularity. Diagnostic evaluation consists of patient history and physical examination, serum TSH determination, free thyroxine and free triiodothyronine measurements, and imaging studies assessing goiter function, size, and anatomy. If treatment is required, L-thyroxine, thionamides, surgery, radioiodine (I-131), and percutaneous ethanol injection (PEI) are effective in selected patients. In euthyroid patients, L-thyroxine reduces goiter size in some patients, but continued therapy is required to prevent regrowth. Thionamides control the hyperthyroidism of toxic nodular goiter in preparation for more definitive therapy, but are rarely used long term. Surgery and I-131 are most commonly selected for definitive therapy for the toxic AFTA, and the toxic or euthyroid MNG, but PEI is effective in selected toxic AFTAs." @default.
• W2001736286 created "2016-06-24" @default.
• W2001736286 creator A5004639492 @default.
• W2001736286 date "2000-04-01" @default.
• W2001736286 modified "2023-09-30" @default.
• W2001736286 title "Therapeutic options in the management of toxic and nontoxic nodular goiter" @default.
• W2001736286 cites W1967300056 @default.
• W2001736286 cites W1974279346 @default.
• W2001736286 cites W1974933152 @default.
• W2001736286 cites W1975290953 @default.
• W2001736286 cites W1998680549 @default.
• W2001736286 cites W2007974905 @default.
• W2001736286 cites W2011035900 @default.
• W2001736286 cites W2015287699 @default.
• W2001736286 cites W2017995060 @default.
• W2001736286 cites W2018068038 @default.
• W2001736286 cites W2018454192 @default.
• W2001736286 cites W2026199326 @default.
• W2001736286 cites W2030303564 @default.
• W2001736286 cites W2033171689 @default.
• W2001736286 cites W2035005868 @default.
• W2001736286 cites W2036008981 @default.
• W2001736286 cites W2036317296 @default.
• W2001736286 cites W2038217607 @default.
• W2001736286 cites W2067502255 @default.
• W2001736286 cites W2072776543 @default.
• W2001736286 cites W2073123957 @default.
• W2001736286 cites W2077293571 @default.
• W2001736286 cites W2077962745 @default.
• W2001736286 cites W2099441829 @default.
• W2001736286 cites W2123530554 @default.
• W2001736286 cites W2131733304 @default.
• W2001736286 cites W2168509502 @default.
• W2001736286 cites W2315297187 @default.
• W2001736286 cites W4206388996 @default.
• W2001736286 cites W81582517 @default.
• W2001736286 doi "https://doi.org/10.1053/nm.2000.4597" @default.
• W2001736286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10787189" @default.
• W2001736286 hasPublicationYear "2000" @default.
• W2001736286 type Work @default.
• W2001736286 sameAs 2001736286 @default.
• W2001736286 citedByCount "42" @default.
• W2001736286 countsByYear W20017362862012 @default.
• W2001736286 countsByYear W20017362862014 @default.
• W2001736286 countsByYear W20017362862015 @default.
• W2001736286 countsByYear W20017362862016 @default.
• W2001736286 countsByYear W20017362862018 @default.
• W2001736286 countsByYear W20017362862020 @default.
• W2001736286 countsByYear W20017362862021 @default.
• W2001736286 countsByYear W20017362862022 @default.
• W2001736286 countsByYear W20017362862023 @default.
• W2001736286 crossrefType "journal-article" @default.
• W2001736286 hasAuthorship W2001736286A5004639492 @default.
• W2001736286 hasConcept C126322002 @default.
• W2001736286 hasConcept C134018914 @default.
• W2001736286 hasConcept C142724271 @default.
• W2001736286 hasConcept C2776254400 @default.
• W2001736286 hasConcept C2777195454 @default.
• W2001736286 hasConcept C2777377203 @default.
• W2001736286 hasConcept C2777428134 @default.
• W2001736286 hasConcept C2777802297 @default.
• W2001736286 hasConcept C2778288131 @default.
• W2001736286 hasConcept C2778660577 @default.
• W2001736286 hasConcept C2778902805 @default.
• W2001736286 hasConcept C2779022025 @default.
• W2001736286 hasConcept C2779864613 @default.
• W2001736286 hasConcept C2993291352 @default.
• W2001736286 hasConcept C526584372 @default.
• W2001736286 hasConcept C71924100 @default.
• W2001736286 hasConcept C90924648 @default.
• W2001736286 hasConceptScore W2001736286C126322002 @default.
• W2001736286 hasConceptScore W2001736286C134018914 @default.
• W2001736286 hasConceptScore W2001736286C142724271 @default.
• W2001736286 hasConceptScore W2001736286C2776254400 @default.
• W2001736286 hasConceptScore W2001736286C2777195454 @default.
• W2001736286 hasConceptScore W2001736286C2777377203 @default.
• W2001736286 hasConceptScore W2001736286C2777428134 @default.
• W2001736286 hasConceptScore W2001736286C2777802297 @default.
• W2001736286 hasConceptScore W2001736286C2778288131 @default.
• W2001736286 hasConceptScore W2001736286C2778660577 @default.
• W2001736286 hasConceptScore W2001736286C2778902805 @default.
• W2001736286 hasConceptScore W2001736286C2779022025 @default.
• W2001736286 hasConceptScore W2001736286C2779864613 @default.
• W2001736286 hasConceptScore W2001736286C2993291352 @default.
• W2001736286 hasConceptScore W2001736286C526584372 @default.
• W2001736286 hasConceptScore W2001736286C71924100 @default.
• W2001736286 hasConceptScore W2001736286C90924648 @default.
• W2001736286 hasIssue "2" @default.
• W2001736286 hasLocation W20017362861 @default.
• W2001736286 hasLocation W20017362862 @default.
• W2001736286 hasOpenAccess W2001736286 @default.
• W2001736286 hasPrimaryLocation W20017362861 @default.
• W2001736286 hasRelatedWork W2020966517 @default.
• W2001736286 hasRelatedWork W2065348237 @default.
• W2001736286 hasRelatedWork W2070069097 @default.
• W2001736286 hasRelatedWork W2080164112 @default.
• W2001736286 hasRelatedWork W2082815614 @default.
• W2001736286 hasRelatedWork W2083714907 @default.

• next