FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001750210> ?p ?o ?g. }

• W2001750210 endingPage "254.e5" @default.
• W2001750210 startingPage "254.e1" @default.
• W2001750210 abstract "Objective Various tocolytics are used to suppress uterine contractility in patients in preterm labor. Progesterone (P4) is used in patients at high risk for preterm delivery. In this study, we evaluated the effects of various tocolytics with and without P4 to examine effects on uterine contractility. Study Design Uterine tissues (n = 280) from women undergoing cesarean at term were exposed in vitro to various agents (vehicle, magnesium sulfate [MgSO4], nifedipine, indomethacin, or pinacidil–all with and without P4). Contractility was measured before and after addition of the various agents. Results P4 alone at 10–5 mol/L concentration has little effect to inhibit contractility (P ≥ .05). MgSO4 (2-8 × 10–3 mol/L) inhibits uterine contractility (P < .05) but there is no change when combined with P4 (P > .05). Nifedipine (10–8 mol/L) and indomethacin (10–5 mol/L) inhibit contractions alone (P < .05) and to a greater extent when combined with P4 (P < .05). P4 significantly (P < .05) reduced the effects of pinacidil (10–6.5 mol/L). Conclusion Combinations of P4 with nifedipine or indomethacin, but not MgSO4, might be used to effectively suppress preterm labor. Various tocolytics are used to suppress uterine contractility in patients in preterm labor. Progesterone (P4) is used in patients at high risk for preterm delivery. In this study, we evaluated the effects of various tocolytics with and without P4 to examine effects on uterine contractility. Uterine tissues (n = 280) from women undergoing cesarean at term were exposed in vitro to various agents (vehicle, magnesium sulfate [MgSO4], nifedipine, indomethacin, or pinacidil–all with and without P4). Contractility was measured before and after addition of the various agents. P4 alone at 10–5 mol/L concentration has little effect to inhibit contractility (P ≥ .05). MgSO4 (2-8 × 10–3 mol/L) inhibits uterine contractility (P < .05) but there is no change when combined with P4 (P > .05). Nifedipine (10–8 mol/L) and indomethacin (10–5 mol/L) inhibit contractions alone (P < .05) and to a greater extent when combined with P4 (P < .05). P4 significantly (P < .05) reduced the effects of pinacidil (10–6.5 mol/L). Combinations of P4 with nifedipine or indomethacin, but not MgSO4, might be used to effectively suppress preterm labor." @default.
• W2001750210 created "2016-06-24" @default.
• W2001750210 creator A5024008300 @default.
• W2001750210 creator A5029930125 @default.
• W2001750210 creator A5037233008 @default.
• W2001750210 creator A5046471717 @default.
• W2001750210 creator A5063215022 @default.
• W2001750210 creator A5078187610 @default.
• W2001750210 date "2012-03-01" @default.
• W2001750210 modified "2023-10-18" @default.
• W2001750210 title "Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies" @default.
• W2001750210 cites W2003105309 @default.
• W2001750210 cites W2019091990 @default.
• W2001750210 cites W2023852827 @default.
• W2001750210 cites W2065614074 @default.
• W2001750210 cites W2075216461 @default.
• W2001750210 cites W2075719860 @default.
• W2001750210 cites W2078850564 @default.
• W2001750210 cites W2080017495 @default.
• W2001750210 cites W2089017675 @default.
• W2001750210 cites W2100645707 @default.
• W2001750210 cites W2100786900 @default.
• W2001750210 cites W2123364364 @default.
• W2001750210 cites W2127510146 @default.
• W2001750210 cites W2136362992 @default.
• W2001750210 cites W2144171496 @default.
• W2001750210 cites W2329971271 @default.
• W2001750210 cites W2340017361 @default.
• W2001750210 cites W4240122463 @default.
• W2001750210 cites W4250396314 @default.
• W2001750210 doi "https://doi.org/10.1016/j.ajog.2011.12.011" @default.
• W2001750210 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22244470" @default.
• W2001750210 hasPublicationYear "2012" @default.
• W2001750210 type Work @default.
• W2001750210 sameAs 2001750210 @default.
• W2001750210 citedByCount "29" @default.
• W2001750210 countsByYear W20017502102013 @default.
• W2001750210 countsByYear W20017502102014 @default.
• W2001750210 countsByYear W20017502102015 @default.
• W2001750210 countsByYear W20017502102016 @default.
• W2001750210 countsByYear W20017502102017 @default.
• W2001750210 countsByYear W20017502102018 @default.
• W2001750210 countsByYear W20017502102019 @default.
• W2001750210 countsByYear W20017502102020 @default.
• W2001750210 countsByYear W20017502102021 @default.
• W2001750210 countsByYear W20017502102022 @default.
• W2001750210 countsByYear W20017502102023 @default.
• W2001750210 crossrefType "journal-article" @default.
• W2001750210 hasAuthorship W2001750210A5024008300 @default.
• W2001750210 hasAuthorship W2001750210A5029930125 @default.
• W2001750210 hasAuthorship W2001750210A5037233008 @default.
• W2001750210 hasAuthorship W2001750210A5046471717 @default.
• W2001750210 hasAuthorship W2001750210A5063215022 @default.
• W2001750210 hasAuthorship W2001750210A5078187610 @default.
• W2001750210 hasConcept C126322002 @default.
• W2001750210 hasConcept C134018914 @default.
• W2001750210 hasConcept C2776766599 @default.
• W2001750210 hasConcept C2778164554 @default.
• W2001750210 hasConcept C2779066055 @default.
• W2001750210 hasConcept C2779066535 @default.
• W2001750210 hasConcept C2779234561 @default.
• W2001750210 hasConcept C2780931799 @default.
• W2001750210 hasConcept C2908881489 @default.
• W2001750210 hasConcept C3019152611 @default.
• W2001750210 hasConcept C39133596 @default.
• W2001750210 hasConcept C46973012 @default.
• W2001750210 hasConcept C519063684 @default.
• W2001750210 hasConcept C54355233 @default.
• W2001750210 hasConcept C71924100 @default.
• W2001750210 hasConcept C86803240 @default.
• W2001750210 hasConceptScore W2001750210C126322002 @default.
• W2001750210 hasConceptScore W2001750210C134018914 @default.
• W2001750210 hasConceptScore W2001750210C2776766599 @default.
• W2001750210 hasConceptScore W2001750210C2778164554 @default.
• W2001750210 hasConceptScore W2001750210C2779066055 @default.
• W2001750210 hasConceptScore W2001750210C2779066535 @default.
• W2001750210 hasConceptScore W2001750210C2779234561 @default.
• W2001750210 hasConceptScore W2001750210C2780931799 @default.
• W2001750210 hasConceptScore W2001750210C2908881489 @default.
• W2001750210 hasConceptScore W2001750210C3019152611 @default.
• W2001750210 hasConceptScore W2001750210C39133596 @default.
• W2001750210 hasConceptScore W2001750210C46973012 @default.
• W2001750210 hasConceptScore W2001750210C519063684 @default.
• W2001750210 hasConceptScore W2001750210C54355233 @default.
• W2001750210 hasConceptScore W2001750210C71924100 @default.
• W2001750210 hasConceptScore W2001750210C86803240 @default.
• W2001750210 hasIssue "3" @default.
• W2001750210 hasLocation W20017502101 @default.
• W2001750210 hasLocation W20017502102 @default.
• W2001750210 hasOpenAccess W2001750210 @default.
• W2001750210 hasPrimaryLocation W20017502101 @default.
• W2001750210 hasRelatedWork W1973534523 @default.
• W2001750210 hasRelatedWork W2001750210 @default.
• W2001750210 hasRelatedWork W2067811371 @default.
• W2001750210 hasRelatedWork W2068166714 @default.
• W2001750210 hasRelatedWork W2092508028 @default.
• W2001750210 hasRelatedWork W2143190462 @default.
• W2001750210 hasRelatedWork W2408204837 @default.

• next