Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001820141> ?p ?o ?g. }
- W2001820141 endingPage "520" @default.
- W2001820141 startingPage "511" @default.
- W2001820141 abstract "The thermal stability of the trimeric species formed by seven type I collagen CNBr peptides was determined at neutral and acidic pH. Melting temperature of peptide trimers and free energy change for monomer to trimer transition were used as indices of trimer stability. A greater stability at neutral pH than at acidic pH was found for all peptides analysed because in most conditions an entropic gain overwhelms an enthalpic cost. Enthalpic reasons are prevailing only in some conditions of the more acidic peptides. The overlap zone of type I collagen fibrils is more basic than the gap zone and is therefore more sensitive to variations of pH from neutral to acidic, e.g. in bone degradation when osteoclasts acidify the lacuna lying between cell and bone. Peptide trimer stability in neutral conditions is influenced also by the chaotropic nature and the concentration of three anions: chloride, sulfate and phosphate. This was more evident for sulfate at the highest concentration used (0.5 M) when a greater stability is caused by entropic reasons. The contribution of hydroxyproline to the stability of peptide trimers is greater at neutral than at acidic pH, particularly at the highest concentration of sulfate. All our data indicate that pH, chaotropic nature and concentration of three anions influence the networks of hydrogen bonds present in the collagen triple helical structure." @default.
- W2001820141 created "2016-06-24" @default.
- W2001820141 creator A5008025123 @default.
- W2001820141 creator A5030008425 @default.
- W2001820141 creator A5082819337 @default.
- W2001820141 creator A5089291519 @default.
- W2001820141 date "2000-11-01" @default.
- W2001820141 modified "2023-10-01" @default.
- W2001820141 title "Stability and networks of hydrogen bonds of the collagen triple helical structure: influence of pH and chaotropic nature of three anions" @default.
- W2001820141 cites W1555450944 @default.
- W2001820141 cites W1645361893 @default.
- W2001820141 cites W1762414595 @default.
- W2001820141 cites W1832142381 @default.
- W2001820141 cites W1890886311 @default.
- W2001820141 cites W1963249122 @default.
- W2001820141 cites W1964556609 @default.
- W2001820141 cites W1967550539 @default.
- W2001820141 cites W1968024679 @default.
- W2001820141 cites W1970087440 @default.
- W2001820141 cites W1979221090 @default.
- W2001820141 cites W1998719385 @default.
- W2001820141 cites W1999793517 @default.
- W2001820141 cites W2003292237 @default.
- W2001820141 cites W2006693760 @default.
- W2001820141 cites W2009672068 @default.
- W2001820141 cites W2009687088 @default.
- W2001820141 cites W2026763399 @default.
- W2001820141 cites W2028941595 @default.
- W2001820141 cites W2036188479 @default.
- W2001820141 cites W2053168080 @default.
- W2001820141 cites W2055746966 @default.
- W2001820141 cites W2066728517 @default.
- W2001820141 cites W2068118841 @default.
- W2001820141 cites W2068318144 @default.
- W2001820141 cites W2070643634 @default.
- W2001820141 cites W2071195910 @default.
- W2001820141 cites W2075453642 @default.
- W2001820141 cites W2078645571 @default.
- W2001820141 cites W2081227300 @default.
- W2001820141 cites W2088307950 @default.
- W2001820141 cites W2088394545 @default.
- W2001820141 cites W2091470384 @default.
- W2001820141 cites W2093019606 @default.
- W2001820141 cites W2093871575 @default.
- W2001820141 cites W2095351662 @default.
- W2001820141 cites W2100837269 @default.
- W2001820141 cites W2135964386 @default.
- W2001820141 cites W2136758973 @default.
- W2001820141 cites W2142395889 @default.
- W2001820141 cites W2144985870 @default.
- W2001820141 cites W2230039189 @default.
- W2001820141 cites W4249223763 @default.
- W2001820141 cites W4300941906 @default.
- W2001820141 doi "https://doi.org/10.1016/s0945-053x(00)00096-2" @default.
- W2001820141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11068205" @default.
- W2001820141 hasPublicationYear "2000" @default.
- W2001820141 type Work @default.
- W2001820141 sameAs 2001820141 @default.
- W2001820141 citedByCount "54" @default.
- W2001820141 countsByYear W20018201412012 @default.
- W2001820141 countsByYear W20018201412013 @default.
- W2001820141 countsByYear W20018201412014 @default.
- W2001820141 countsByYear W20018201412015 @default.
- W2001820141 countsByYear W20018201412016 @default.
- W2001820141 countsByYear W20018201412017 @default.
- W2001820141 countsByYear W20018201412018 @default.
- W2001820141 countsByYear W20018201412019 @default.
- W2001820141 countsByYear W20018201412020 @default.
- W2001820141 countsByYear W20018201412021 @default.
- W2001820141 countsByYear W20018201412022 @default.
- W2001820141 countsByYear W20018201412023 @default.
- W2001820141 crossrefType "journal-article" @default.
- W2001820141 hasAuthorship W2001820141A5008025123 @default.
- W2001820141 hasAuthorship W2001820141A5030008425 @default.
- W2001820141 hasAuthorship W2001820141A5082819337 @default.
- W2001820141 hasAuthorship W2001820141A5089291519 @default.
- W2001820141 hasConcept C102362939 @default.
- W2001820141 hasConcept C112887158 @default.
- W2001820141 hasConcept C155181932 @default.
- W2001820141 hasConcept C166940927 @default.
- W2001820141 hasConcept C178790620 @default.
- W2001820141 hasConcept C181199279 @default.
- W2001820141 hasConcept C185592680 @default.
- W2001820141 hasConcept C2776403692 @default.
- W2001820141 hasConcept C2777654166 @default.
- W2001820141 hasConcept C2779281246 @default.
- W2001820141 hasConcept C2779546866 @default.
- W2001820141 hasConcept C2779797417 @default.
- W2001820141 hasConcept C32909587 @default.
- W2001820141 hasConcept C521977710 @default.
- W2001820141 hasConcept C55493867 @default.
- W2001820141 hasConcept C59061564 @default.
- W2001820141 hasConcept C8010536 @default.
- W2001820141 hasConceptScore W2001820141C102362939 @default.
- W2001820141 hasConceptScore W2001820141C112887158 @default.
- W2001820141 hasConceptScore W2001820141C155181932 @default.
- W2001820141 hasConceptScore W2001820141C166940927 @default.
- W2001820141 hasConceptScore W2001820141C178790620 @default.