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• W2001824048 abstract "An asymmetric synthesis of neurokinin substance P receptor antagonist (+)-L-733,060 starting from enantiomerically pure ethyl (R)-(+)-2,3-epoxypropanoate (ethyl glycidate) is described. The synthesis relies on a diastereoselective reductive amination, regioselective intramolecular epoxide opening, and in situ cyclization as the key steps." @default.
• W2001824048 created "2016-06-24" @default.
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• W2001824048 date "2010-01-01" @default.
• W2001824048 modified "2023-10-16" @default.
• W2001824048 title "A stereoselective synthesis of (+)-L-733,060 from ethyl (R)-(+)-2,3-epoxypropanoate" @default.
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• W2001824048 doi "https://doi.org/10.1016/j.tetasy.2009.12.010" @default.
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