FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001844985> ?p ?o ?g. }

• W2001844985 endingPage "757" @default.
• W2001844985 startingPage "751" @default.
• W2001844985 abstract "Purpose: Comparative evaluation of efficacy of monotherapy with moxifloxacin (0.5%) or gatifloxacin (0.3%) with combination therapy of cefazolin (5%) and tobramycin (1.3%) in treatment of bacterial corneal ulcers. Methods: Patients diagnosed with bacterial keratitis (ulcer diameter 2-8 mm) were randomized to 1 of the 3 treatment groups (tobramycin 1.3% and cefazolin 5%, gatifloxacin 0.3%, or moxifloxacin 0.5%). After obtaining corneal scrapings, assigned study medication was instilled hourly for 48 hours and tapered as per clinical response. Healing of ulcer, duration to cure, adverse reactions, antibiogram profile, treatment failures, final visual acuity, and corneal opacity size were evaluated. Results: A total of 61 patients were enrolled [cefazolin and tobramycin (n = 20), gatifloxacin (n = 21), and moxifloxacin (n = 20)]. Overall, 57 patients (93%) healed on treatment. On comparison of the mean time taken to heal, no statistically significant difference was found among all the 3 treatment groups (P = 0.98). Positive bacterial culture was obtained in only 38 patients (62%). There was no significant difference in the bacterial isolates in each treatment group. There were 4 (7%) treatment failures (perforation or nonhealing ulcer): 1 (5%) each in moxifloxacin and gatifloxacin group and 2 (10%) in fortified antibiotics group. All regimens were well tolerated. Conclusion: The study failed to find a difference in the efficacy of monotherapy with fourth-generation fluoroquinolones in the treatment of bacterial corneal ulcers of 2-8 mm size when compared with combination therapy of fortified antibiotics." @default.
• W2001844985 created "2016-06-24" @default.
• W2001844985 creator A5017638830 @default.
• W2001844985 creator A5033355902 @default.
• W2001844985 creator A5036098245 @default.
• W2001844985 creator A5052285436 @default.
• W2001844985 creator A5059159247 @default.
• W2001844985 creator A5066204663 @default.
• W2001844985 creator A5070023095 @default.
• W2001844985 creator A5078444378 @default.
• W2001844985 creator A5080287619 @default.
• W2001844985 date "2010-07-01" @default.
• W2001844985 modified "2023-10-16" @default.
• W2001844985 title "Randomized Clinical Study for Comparative Evaluation of Fourth-Generation Fluoroquinolones With the Combination of Fortified Antibiotics in the Treatment of Bacterial Corneal Ulcers" @default.
• W2001844985 cites W1507181797 @default.
• W2001844985 cites W1963939248 @default.
• W2001844985 cites W1964956656 @default.
• W2001844985 cites W1985414929 @default.
• W2001844985 cites W1999220050 @default.
• W2001844985 cites W1999614061 @default.
• W2001844985 cites W2006698976 @default.
• W2001844985 cites W2010872522 @default.
• W2001844985 cites W2014825458 @default.
• W2001844985 cites W2016660338 @default.
• W2001844985 cites W20224748 @default.
• W2001844985 cites W2025170824 @default.
• W2001844985 cites W2026007068 @default.
• W2001844985 cites W2043563048 @default.
• W2001844985 cites W2050908776 @default.
• W2001844985 cites W2058791113 @default.
• W2001844985 cites W2069340075 @default.
• W2001844985 cites W2069702799 @default.
• W2001844985 cites W2082205722 @default.
• W2001844985 cites W2091240031 @default.
• W2001844985 cites W2094350994 @default.
• W2001844985 cites W2096255649 @default.
• W2001844985 cites W2109203736 @default.
• W2001844985 cites W2131380679 @default.
• W2001844985 cites W2132326533 @default.
• W2001844985 cites W2136931384 @default.
• W2001844985 cites W2140620077 @default.
• W2001844985 cites W2155930383 @default.
• W2001844985 cites W2161947080 @default.
• W2001844985 doi "https://doi.org/10.1097/ico.0b013e3181ca2ba3" @default.
• W2001844985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20489580" @default.
• W2001844985 hasPublicationYear "2010" @default.
• W2001844985 type Work @default.
• W2001844985 sameAs 2001844985 @default.
• W2001844985 citedByCount "50" @default.
• W2001844985 countsByYear W20018449852012 @default.
• W2001844985 countsByYear W20018449852013 @default.
• W2001844985 countsByYear W20018449852014 @default.
• W2001844985 countsByYear W20018449852015 @default.
• W2001844985 countsByYear W20018449852016 @default.
• W2001844985 countsByYear W20018449852017 @default.
• W2001844985 countsByYear W20018449852018 @default.
• W2001844985 countsByYear W20018449852019 @default.
• W2001844985 countsByYear W20018449852020 @default.
• W2001844985 countsByYear W20018449852021 @default.
• W2001844985 countsByYear W20018449852022 @default.
• W2001844985 countsByYear W20018449852023 @default.
• W2001844985 crossrefType "journal-article" @default.
• W2001844985 hasAuthorship W2001844985A5017638830 @default.
• W2001844985 hasAuthorship W2001844985A5033355902 @default.
• W2001844985 hasAuthorship W2001844985A5036098245 @default.
• W2001844985 hasAuthorship W2001844985A5052285436 @default.
• W2001844985 hasAuthorship W2001844985A5059159247 @default.
• W2001844985 hasAuthorship W2001844985A5066204663 @default.
• W2001844985 hasAuthorship W2001844985A5070023095 @default.
• W2001844985 hasAuthorship W2001844985A5078444378 @default.
• W2001844985 hasAuthorship W2001844985A5080287619 @default.
• W2001844985 hasConcept C118487528 @default.
• W2001844985 hasConcept C126322002 @default.
• W2001844985 hasConcept C141071460 @default.
• W2001844985 hasConcept C2775832221 @default.
• W2001844985 hasConcept C2777653605 @default.
• W2001844985 hasConcept C2778353156 @default.
• W2001844985 hasConcept C2778836808 @default.
• W2001844985 hasConcept C2778974779 @default.
• W2001844985 hasConcept C2781276175 @default.
• W2001844985 hasConcept C501593827 @default.
• W2001844985 hasConcept C71924100 @default.
• W2001844985 hasConcept C86803240 @default.
• W2001844985 hasConcept C89423630 @default.
• W2001844985 hasConceptScore W2001844985C118487528 @default.
• W2001844985 hasConceptScore W2001844985C126322002 @default.
• W2001844985 hasConceptScore W2001844985C141071460 @default.
• W2001844985 hasConceptScore W2001844985C2775832221 @default.
• W2001844985 hasConceptScore W2001844985C2777653605 @default.
• W2001844985 hasConceptScore W2001844985C2778353156 @default.
• W2001844985 hasConceptScore W2001844985C2778836808 @default.
• W2001844985 hasConceptScore W2001844985C2778974779 @default.
• W2001844985 hasConceptScore W2001844985C2781276175 @default.
• W2001844985 hasConceptScore W2001844985C501593827 @default.
• W2001844985 hasConceptScore W2001844985C71924100 @default.
• W2001844985 hasConceptScore W2001844985C86803240 @default.
• W2001844985 hasConceptScore W2001844985C89423630 @default.
• W2001844985 hasIssue "7" @default.

• next