Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001857415> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2001857415 endingPage "62" @default.
- W2001857415 startingPage "55" @default.
- W2001857415 abstract "Unfused palatal shelves from day 15 rat embryos were cultured with their medial-edge epithelium in contact. After 24 h, the epithelial surfaces of apposing shelves had adhered, and the epithelium showed evidence of degeneration such as a thinning of the midline seam, a loss of morphologically distinct cell types, degradation of the basement membrane and the appearance of lysosomal bodies. The addition of epidermal growth factor (EGF) inhibited all these degenerative processes and increased the number of desmosomes and tonofilaments as well. Shelves cultured in the presence of EGF+dibutyryl cyclic AMP (db-cAMP)+theophylline showed the degenerative changes seen in control epithelia but also showed a large number of desmosomes and tonofilaments. Labeling studies with [3H]thymidine ([3H]TdR) showed that EGF did not stimulate DNA synthesis in medial-edge cells of the day 15 rat palatal shelf. These results indicate that the inhibition of palatal epithelial cell death by EGF can be prevented by db-cAMP plus theophylline suggesting that some effects of EGF may be mediated through lowered levels of cAMP." @default.
- W2001857415 created "2016-06-24" @default.
- W2001857415 creator A5033978964 @default.
- W2001857415 creator A5057816070 @default.
- W2001857415 date "1977-04-01" @default.
- W2001857415 modified "2023-10-14" @default.
- W2001857415 title "Elevated levels of cAMP alters the effect of epidermal growth factor in vitro on programmed cell death in the secondary palatal epithelium" @default.
- W2001857415 cites W1554132658 @default.
- W2001857415 cites W1965472132 @default.
- W2001857415 cites W1984398282 @default.
- W2001857415 cites W1992113468 @default.
- W2001857415 cites W1996683778 @default.
- W2001857415 cites W2019126938 @default.
- W2001857415 cites W2022773184 @default.
- W2001857415 cites W2023944459 @default.
- W2001857415 cites W2024068070 @default.
- W2001857415 cites W2029948342 @default.
- W2001857415 cites W2044137003 @default.
- W2001857415 cites W2055926219 @default.
- W2001857415 cites W2069126696 @default.
- W2001857415 cites W2074504054 @default.
- W2001857415 cites W2074804865 @default.
- W2001857415 cites W2081606453 @default.
- W2001857415 cites W2109401564 @default.
- W2001857415 doi "https://doi.org/10.1016/0014-4827(77)90240-3" @default.
- W2001857415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/192566" @default.
- W2001857415 hasPublicationYear "1977" @default.
- W2001857415 type Work @default.
- W2001857415 sameAs 2001857415 @default.
- W2001857415 citedByCount "67" @default.
- W2001857415 countsByYear W20018574152017 @default.
- W2001857415 crossrefType "journal-article" @default.
- W2001857415 hasAuthorship W2001857415A5033978964 @default.
- W2001857415 hasAuthorship W2001857415A5057816070 @default.
- W2001857415 hasConcept C126322002 @default.
- W2001857415 hasConcept C134018914 @default.
- W2001857415 hasConcept C1491633281 @default.
- W2001857415 hasConcept C190283241 @default.
- W2001857415 hasConcept C202751555 @default.
- W2001857415 hasConcept C2776193487 @default.
- W2001857415 hasConcept C2776362946 @default.
- W2001857415 hasConcept C2777108182 @default.
- W2001857415 hasConcept C2778095195 @default.
- W2001857415 hasConcept C31573885 @default.
- W2001857415 hasConcept C529295009 @default.
- W2001857415 hasConcept C54355233 @default.
- W2001857415 hasConcept C55493867 @default.
- W2001857415 hasConcept C64241487 @default.
- W2001857415 hasConcept C71924100 @default.
- W2001857415 hasConcept C81885089 @default.
- W2001857415 hasConcept C86803240 @default.
- W2001857415 hasConcept C95444343 @default.
- W2001857415 hasConceptScore W2001857415C126322002 @default.
- W2001857415 hasConceptScore W2001857415C134018914 @default.
- W2001857415 hasConceptScore W2001857415C1491633281 @default.
- W2001857415 hasConceptScore W2001857415C190283241 @default.
- W2001857415 hasConceptScore W2001857415C202751555 @default.
- W2001857415 hasConceptScore W2001857415C2776193487 @default.
- W2001857415 hasConceptScore W2001857415C2776362946 @default.
- W2001857415 hasConceptScore W2001857415C2777108182 @default.
- W2001857415 hasConceptScore W2001857415C2778095195 @default.
- W2001857415 hasConceptScore W2001857415C31573885 @default.
- W2001857415 hasConceptScore W2001857415C529295009 @default.
- W2001857415 hasConceptScore W2001857415C54355233 @default.
- W2001857415 hasConceptScore W2001857415C55493867 @default.
- W2001857415 hasConceptScore W2001857415C64241487 @default.
- W2001857415 hasConceptScore W2001857415C71924100 @default.
- W2001857415 hasConceptScore W2001857415C81885089 @default.
- W2001857415 hasConceptScore W2001857415C86803240 @default.
- W2001857415 hasConceptScore W2001857415C95444343 @default.
- W2001857415 hasIssue "1" @default.
- W2001857415 hasLocation W20018574151 @default.
- W2001857415 hasLocation W20018574152 @default.
- W2001857415 hasOpenAccess W2001857415 @default.
- W2001857415 hasPrimaryLocation W20018574151 @default.
- W2001857415 hasRelatedWork W1965207919 @default.
- W2001857415 hasRelatedWork W1990931289 @default.
- W2001857415 hasRelatedWork W1998639344 @default.
- W2001857415 hasRelatedWork W2016552349 @default.
- W2001857415 hasRelatedWork W2021560856 @default.
- W2001857415 hasRelatedWork W2032639135 @default.
- W2001857415 hasRelatedWork W2041176106 @default.
- W2001857415 hasRelatedWork W2070641839 @default.
- W2001857415 hasRelatedWork W2101277166 @default.
- W2001857415 hasRelatedWork W2155710199 @default.
- W2001857415 hasVolume "106" @default.
- W2001857415 isParatext "false" @default.
- W2001857415 isRetracted "false" @default.
- W2001857415 magId "2001857415" @default.
- W2001857415 workType "article" @default.