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- W2001868911 abstract "Skeletal muscle mitochondria, prepared by methods using the proteinase, Nagarse, are able to oxidize fatty acylcarnitines but not long-chain free fatty acids. Evidence obtained shows that this is not due to a lack of ATP-dependent long-chain fatty acid activating enzyme but because of the marked selective susceptibility of this enzyme to the action of Nagarse. The carnitine palmityltransferase activity is relatively stable to Nagarse. Exposure of the rat liver mitochondria to Nagarse also led to a loss of the ATP-dependent long-chain fatty acid activating enzyme but not that of monoamine oxidase. These results suggest that the ATP-dependent long-chain fatty acid activating enzyme may be localized on the outer side of the outer mitochondrial membrane." @default.
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- W2001868911 date "1970-02-01" @default.
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- W2001868911 title "Preferential loss of ATP-dependent long-chain fatty acid activating enzyme in mitochondria prepared using nagarse" @default.
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- W2001868911 doi "https://doi.org/10.1016/0005-2760(70)90216-x" @default.
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