Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001890931> ?p ?o ?g. }
- W2001890931 endingPage "1909" @default.
- W2001890931 startingPage "1905" @default.
- W2001890931 abstract "To compare the effect of levodopa-carbidopa on the visual outcome of patients with indirect traumatic optic neuropathy (ITON), this randomized, double-blind, placebo-controlled study was conducted on 32 patients with ITON within 6 days after trauma. Patients underwent a complete ocular examination, pattern visual evoked potential (PVEP) testing, and high-resolution orbital computed tomography (CT) scanning. All patients received high-dose intravenous methylprednisolone, and levodopa was also administered to the levodopa group. The main outcome measures were best corrected visual acuity and PVEP results at the last-completed examination. The study was completed on 16 patients in the levodopa group and 10 patients in the placebo group because the others were lost to follow-up. There were no statistically significant differences for age, sex, involved eye, ocular and CT scan findings, pretreatment visual acuity, frequency of recordable PVEPs, and follow-up. In the levodopa group the visual acuity improved significantly after treatment (p = 0.009), but not in the placebo group (p = 0.34). After treatment the visual acuity in the levodopa group was 2.1 ± 2.1, and in the placebo group was 3.9 ± 1.2 (p = 0.008). In those who had visual acuity less than or equal to figure count, significant improvement in visual acuity was observed in the levodopa group (p = 0.03), but not in the placebo group (p = 0.34). However, the final visual acuity in these patients was comparable after treatment (p = 0.21). Nine patients (56.2%) in the levodopa group, and 1 (10%) in the placebo group, experienced improvement in visual acuity (p = 0.02). The frequency of unrecordable PVEPs were comparable in both groups (p = 0.09). Patients treated with levodopa within 6 days of onset of ITON were more likely to experience improvement in visual acuity than those in the placebo group." @default.
- W2001890931 created "2016-06-24" @default.
- W2001890931 creator A5015330550 @default.
- W2001890931 creator A5037995236 @default.
- W2001890931 creator A5041298248 @default.
- W2001890931 date "2010-10-01" @default.
- W2001890931 modified "2023-10-16" @default.
- W2001890931 title "Levodopa-Carbidopa May Improve Vision Loss in Indirect Traumatic Optic Neuropathy" @default.
- W2001890931 cites W106986633 @default.
- W2001890931 cites W1853581304 @default.
- W2001890931 cites W1969334748 @default.
- W2001890931 cites W1969705472 @default.
- W2001890931 cites W1972653353 @default.
- W2001890931 cites W1975172226 @default.
- W2001890931 cites W1981933094 @default.
- W2001890931 cites W1987242085 @default.
- W2001890931 cites W1993662972 @default.
- W2001890931 cites W2009501958 @default.
- W2001890931 cites W2015673682 @default.
- W2001890931 cites W2018039000 @default.
- W2001890931 cites W2023155505 @default.
- W2001890931 cites W2024251897 @default.
- W2001890931 cites W2036473770 @default.
- W2001890931 cites W2040842994 @default.
- W2001890931 cites W2042639174 @default.
- W2001890931 cites W2057243099 @default.
- W2001890931 cites W2063459811 @default.
- W2001890931 cites W2065059350 @default.
- W2001890931 cites W2070208397 @default.
- W2001890931 cites W2071040035 @default.
- W2001890931 cites W2071417712 @default.
- W2001890931 cites W2076258282 @default.
- W2001890931 cites W2086554526 @default.
- W2001890931 cites W2106313446 @default.
- W2001890931 cites W2114680163 @default.
- W2001890931 cites W2120292864 @default.
- W2001890931 cites W2120737609 @default.
- W2001890931 cites W2147127921 @default.
- W2001890931 doi "https://doi.org/10.1089/neu.2010.1362" @default.
- W2001890931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20649490" @default.
- W2001890931 hasPublicationYear "2010" @default.
- W2001890931 type Work @default.
- W2001890931 sameAs 2001890931 @default.
- W2001890931 citedByCount "8" @default.
- W2001890931 countsByYear W20018909312015 @default.
- W2001890931 countsByYear W20018909312016 @default.
- W2001890931 countsByYear W20018909312018 @default.
- W2001890931 countsByYear W20018909312021 @default.
- W2001890931 countsByYear W20018909312022 @default.
- W2001890931 crossrefType "journal-article" @default.
- W2001890931 hasAuthorship W2001890931A5015330550 @default.
- W2001890931 hasAuthorship W2001890931A5037995236 @default.
- W2001890931 hasAuthorship W2001890931A5041298248 @default.
- W2001890931 hasConcept C118487528 @default.
- W2001890931 hasConcept C126322002 @default.
- W2001890931 hasConcept C141071460 @default.
- W2001890931 hasConcept C142724271 @default.
- W2001890931 hasConcept C204787440 @default.
- W2001890931 hasConcept C27081682 @default.
- W2001890931 hasConcept C2776754145 @default.
- W2001890931 hasConcept C2778233873 @default.
- W2001890931 hasConcept C2778257484 @default.
- W2001890931 hasConcept C2779134260 @default.
- W2001890931 hasConcept C2779734285 @default.
- W2001890931 hasConcept C2780304432 @default.
- W2001890931 hasConcept C2780837183 @default.
- W2001890931 hasConcept C42219234 @default.
- W2001890931 hasConcept C71924100 @default.
- W2001890931 hasConceptScore W2001890931C118487528 @default.
- W2001890931 hasConceptScore W2001890931C126322002 @default.
- W2001890931 hasConceptScore W2001890931C141071460 @default.
- W2001890931 hasConceptScore W2001890931C142724271 @default.
- W2001890931 hasConceptScore W2001890931C204787440 @default.
- W2001890931 hasConceptScore W2001890931C27081682 @default.
- W2001890931 hasConceptScore W2001890931C2776754145 @default.
- W2001890931 hasConceptScore W2001890931C2778233873 @default.
- W2001890931 hasConceptScore W2001890931C2778257484 @default.
- W2001890931 hasConceptScore W2001890931C2779134260 @default.
- W2001890931 hasConceptScore W2001890931C2779734285 @default.
- W2001890931 hasConceptScore W2001890931C2780304432 @default.
- W2001890931 hasConceptScore W2001890931C2780837183 @default.
- W2001890931 hasConceptScore W2001890931C42219234 @default.
- W2001890931 hasConceptScore W2001890931C71924100 @default.
- W2001890931 hasIssue "10" @default.
- W2001890931 hasLocation W20018909311 @default.
- W2001890931 hasLocation W20018909312 @default.
- W2001890931 hasOpenAccess W2001890931 @default.
- W2001890931 hasPrimaryLocation W20018909311 @default.
- W2001890931 hasRelatedWork W1527267522 @default.
- W2001890931 hasRelatedWork W180464959 @default.
- W2001890931 hasRelatedWork W2001890931 @default.
- W2001890931 hasRelatedWork W2024251897 @default.
- W2001890931 hasRelatedWork W2040842994 @default.
- W2001890931 hasRelatedWork W2278253233 @default.
- W2001890931 hasRelatedWork W2400700256 @default.
- W2001890931 hasRelatedWork W2410986393 @default.
- W2001890931 hasRelatedWork W2810991573 @default.
- W2001890931 hasRelatedWork W2992514624 @default.