FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001959175> ?p ?o ?g. }

• W2001959175 endingPage "331" @default.
• W2001959175 startingPage "224" @default.
• W2001959175 abstract "Apolipoprotein E (ApoE) and H (ApoH) genotypes are known to affect plasma lipoprotein concentrations. By modulating transport and entry of the hepatitis B virus into hepatocytes, apolipoproteins may influence the course of infection. To verify this hypothesis, 105 patients with chronic HBV infection were examined. Sixty-two of the patients were followed-up for a median time of 21 years. One hundred two controls were included. ApoE and ApoH genotypes were determined by the restriction fragment length polymorphism method. A trend was found for progressive overrepresentation of ApoE3/E3 among patients with advanced liver disease: 13/27 (48%) of inactive HBV carriers, 36/61 (59%) of chronic hepatitis B patients and 16/17 (94%) of patients who received liver transplants (P < 0.005). Being an E3/* carrier was associated with a lower probability of loss of HBsAg: 9/56 (16%) versus 3/6 (50%) (P < 0.05); it was also associated with a longer time before HBsAg loss (P < 0.05). No influence of ApoH genotypes on clinical outcomes was found. The probability of disease progression was higher, and that of loss of HBsAg was lower, among patients with the ApoE3 allelic variant. Downregulation and/or reduced binding of the LDL receptor may explain the more benign course of hepatitis B among carriers of ApoE2–E4. J. Med. Virol. 82:224–231, 2010. © 2009 Wiley-Liss, Inc." @default.
• W2001959175 created "2016-06-24" @default.
• W2001959175 creator A5000937035 @default.
• W2001959175 creator A5026050138 @default.
• W2001959175 creator A5036666985 @default.
• W2001959175 creator A5043993968 @default.
• W2001959175 creator A5052950973 @default.
• W2001959175 creator A5054586273 @default.
• W2001959175 creator A5060395295 @default.
• W2001959175 creator A5064956279 @default.
• W2001959175 creator A5072500126 @default.
• W2001959175 creator A5073051597 @default.
• W2001959175 creator A5086897284 @default.
• W2001959175 date "2010-02-01" @default.
• W2001959175 modified "2023-10-14" @default.
• W2001959175 title "Genetic polymorphism at the apolipoprotein E locus affects the outcome of chronic hepatitis B" @default.
• W2001959175 cites W1546262989 @default.
• W2001959175 cites W1584708924 @default.
• W2001959175 cites W1838193685 @default.
• W2001959175 cites W1966448677 @default.
• W2001959175 cites W1970365574 @default.
• W2001959175 cites W1978436940 @default.
• W2001959175 cites W1986505810 @default.
• W2001959175 cites W1999898230 @default.
• W2001959175 cites W2007421495 @default.
• W2001959175 cites W2025879508 @default.
• W2001959175 cites W2030675713 @default.
• W2001959175 cites W2034968148 @default.
• W2001959175 cites W2044951291 @default.
• W2001959175 cites W2047235770 @default.
• W2001959175 cites W2052513199 @default.
• W2001959175 cites W2071476028 @default.
• W2001959175 cites W2086824725 @default.
• W2001959175 cites W2091332633 @default.
• W2001959175 cites W2091335487 @default.
• W2001959175 cites W2094605428 @default.
• W2001959175 cites W2097820722 @default.
• W2001959175 cites W2112092292 @default.
• W2001959175 cites W2114063969 @default.
• W2001959175 cites W2114234184 @default.
• W2001959175 cites W2115775400 @default.
• W2001959175 cites W2117380333 @default.
• W2001959175 cites W2118356043 @default.
• W2001959175 cites W2129357356 @default.
• W2001959175 cites W2156015715 @default.
• W2001959175 cites W2164286719 @default.
• W2001959175 cites W2165605507 @default.
• W2001959175 cites W2171069625 @default.
• W2001959175 cites W2172002207 @default.
• W2001959175 cites W2410744250 @default.
• W2001959175 cites W4248206535 @default.
• W2001959175 cites W98152484 @default.
• W2001959175 doi "https://doi.org/10.1002/jmv.21642" @default.
• W2001959175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20029801" @default.
• W2001959175 hasPublicationYear "2010" @default.
• W2001959175 type Work @default.
• W2001959175 sameAs 2001959175 @default.
• W2001959175 citedByCount "13" @default.
• W2001959175 countsByYear W20019591752012 @default.
• W2001959175 countsByYear W20019591752013 @default.
• W2001959175 countsByYear W20019591752014 @default.
• W2001959175 countsByYear W20019591752015 @default.
• W2001959175 countsByYear W20019591752016 @default.
• W2001959175 countsByYear W20019591752018 @default.
• W2001959175 countsByYear W20019591752022 @default.
• W2001959175 countsByYear W20019591752023 @default.
• W2001959175 crossrefType "journal-article" @default.
• W2001959175 hasAuthorship W2001959175A5000937035 @default.
• W2001959175 hasAuthorship W2001959175A5026050138 @default.
• W2001959175 hasAuthorship W2001959175A5036666985 @default.
• W2001959175 hasAuthorship W2001959175A5043993968 @default.
• W2001959175 hasAuthorship W2001959175A5052950973 @default.
• W2001959175 hasAuthorship W2001959175A5054586273 @default.
• W2001959175 hasAuthorship W2001959175A5060395295 @default.
• W2001959175 hasAuthorship W2001959175A5064956279 @default.
• W2001959175 hasAuthorship W2001959175A5072500126 @default.
• W2001959175 hasAuthorship W2001959175A5073051597 @default.
• W2001959175 hasAuthorship W2001959175A5086897284 @default.
• W2001959175 hasConcept C104317684 @default.
• W2001959175 hasConcept C126322002 @default.
• W2001959175 hasConcept C135763542 @default.
• W2001959175 hasConcept C159047783 @default.
• W2001959175 hasConcept C180754005 @default.
• W2001959175 hasConcept C203014093 @default.
• W2001959175 hasConcept C2522874641 @default.
• W2001959175 hasConcept C2777075537 @default.
• W2001959175 hasConcept C2777382497 @default.
• W2001959175 hasConcept C2777410769 @default.
• W2001959175 hasConcept C2778163477 @default.
• W2001959175 hasConcept C2779134260 @default.
• W2001959175 hasConcept C2780072125 @default.
• W2001959175 hasConcept C2780593183 @default.
• W2001959175 hasConcept C54355233 @default.
• W2001959175 hasConcept C57089818 @default.
• W2001959175 hasConcept C62746215 @default.
• W2001959175 hasConcept C71924100 @default.
• W2001959175 hasConcept C84597430 @default.
• W2001959175 hasConcept C86803240 @default.

• next