FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001982092> ?p ?o ?g. }

• W2001982092 endingPage "730" @default.
• W2001982092 startingPage "723" @default.
• W2001982092 abstract "Abstract The purpose of this study was to noninvasively monitor tumor oxygenation and redox status during hyperoxygenation treatment, such as carbogen‐breathing, in a murine tumor model using in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging techniques. The study was performed using implanted lithium phthalocyanine (LiPc) microcrystals as the oximetry probe and 3‐carbamoylproxyl (3‐CP) as the redox probe in RIF‐1 tumors implanted in the upper hind leg of C3H mice. Repetitive measurements of pO 2 from the same tumors as a function of tumor growth (8–24 mm in size) showed that the tumors were hypoxic and that the tumor pO 2 values were decreasing with tumor growth. Carbogen‐breathing mostly showed an increase in the tumor oxygenation, although there were considerable variations in the magnitude of change among the tumors. The pharmacokinetic studies with 3‐CP showed a significant decrease in the overall tumor reduction status in the carbogen‐breathing mice. Spatially resolved (imaging) pharmacokinetic data over the tumor volume were obtained to visualize the distribution of the redox status within the tumor. The redox images of the tumor in the air‐breathing mice showed significant heterogeneity in the magnitude and spatial distribution of reducing equivalents. On carbogen‐breathing the tissue reduction status decreased considerably, with a concomitant decrease in the heterogeneity of distribution of the redox status. The results suggest that 1) carbogen‐breathing considerably enhances tissue oxygenation and significantly decreases the redox status in RIF‐1 tumor, and 2) changes in the magnitude and distribution of the redox status within the tumor volume during carbogen‐breathing are correlated with the increased tissue oxygenation. Magn Reson Med 48:723–730, 2002. © 2002 Wiley‐Liss, Inc." @default.
• W2001982092 created "2016-06-24" @default.
• W2001982092 creator A5000526423 @default.
• W2001982092 creator A5000616950 @default.
• W2001982092 creator A5053625408 @default.
• W2001982092 creator A5066737474 @default.
• W2001982092 creator A5072939048 @default.
• W2001982092 creator A5081250782 @default.
• W2001982092 date "2002-09-26" @default.
• W2001982092 modified "2023-10-14" @default.
• W2001982092 title "In vivo measurement of regional oxygenation and imaging of redox status in RIF‐1 murine tumor: Effect of carbogen‐breathing" @default.
• W2001982092 cites W1842875237 @default.
• W2001982092 cites W1963619696 @default.
• W2001982092 cites W1971231577 @default.
• W2001982092 cites W1973111602 @default.
• W2001982092 cites W1977582438 @default.
• W2001982092 cites W1988958750 @default.
• W2001982092 cites W1996816764 @default.
• W2001982092 cites W1997188535 @default.
• W2001982092 cites W2000584274 @default.
• W2001982092 cites W2005760468 @default.
• W2001982092 cites W2006153373 @default.
• W2001982092 cites W2006654035 @default.
• W2001982092 cites W2011375009 @default.
• W2001982092 cites W2019257406 @default.
• W2001982092 cites W2025050268 @default.
• W2001982092 cites W2025260426 @default.
• W2001982092 cites W2032269386 @default.
• W2001982092 cites W2033400453 @default.
• W2001982092 cites W2044507381 @default.
• W2001982092 cites W2052171115 @default.
• W2001982092 cites W2053084058 @default.
• W2001982092 cites W2060223096 @default.
• W2001982092 cites W2073042132 @default.
• W2001982092 cites W2076254314 @default.
• W2001982092 cites W2082993111 @default.
• W2001982092 cites W2087307074 @default.
• W2001982092 cites W2093771162 @default.
• W2001982092 cites W2094521830 @default.
• W2001982092 cites W2112580440 @default.
• W2001982092 cites W2132878122 @default.
• W2001982092 cites W2144960324 @default.
• W2001982092 cites W2158639810 @default.
• W2001982092 cites W5829969 @default.
• W2001982092 doi "https://doi.org/10.1002/mrm.10254" @default.
• W2001982092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12353291" @default.
• W2001982092 hasPublicationYear "2002" @default.
• W2001982092 type Work @default.
• W2001982092 sameAs 2001982092 @default.
• W2001982092 citedByCount "74" @default.
• W2001982092 countsByYear W20019820922012 @default.
• W2001982092 countsByYear W20019820922013 @default.
• W2001982092 countsByYear W20019820922014 @default.
• W2001982092 countsByYear W20019820922015 @default.
• W2001982092 countsByYear W20019820922016 @default.
• W2001982092 countsByYear W20019820922018 @default.
• W2001982092 countsByYear W20019820922019 @default.
• W2001982092 countsByYear W20019820922020 @default.
• W2001982092 countsByYear W20019820922021 @default.
• W2001982092 countsByYear W20019820922022 @default.
• W2001982092 countsByYear W20019820922023 @default.
• W2001982092 crossrefType "journal-article" @default.
• W2001982092 hasAuthorship W2001982092A5000526423 @default.
• W2001982092 hasAuthorship W2001982092A5000616950 @default.
• W2001982092 hasAuthorship W2001982092A5053625408 @default.
• W2001982092 hasAuthorship W2001982092A5066737474 @default.
• W2001982092 hasAuthorship W2001982092A5072939048 @default.
• W2001982092 hasAuthorship W2001982092A5081250782 @default.
• W2001982092 hasBestOaLocation W20019820921 @default.
• W2001982092 hasConcept C112705442 @default.
• W2001982092 hasConcept C126322002 @default.
• W2001982092 hasConcept C126838900 @default.
• W2001982092 hasConcept C142724271 @default.
• W2001982092 hasConcept C143409427 @default.
• W2001982092 hasConcept C150903083 @default.
• W2001982092 hasConcept C173622453 @default.
• W2001982092 hasConcept C178790620 @default.
• W2001982092 hasConcept C185592680 @default.
• W2001982092 hasConcept C207001950 @default.
• W2001982092 hasConcept C2989005 @default.
• W2001982092 hasConcept C39300077 @default.
• W2001982092 hasConcept C42219234 @default.
• W2001982092 hasConcept C509974204 @default.
• W2001982092 hasConcept C55904794 @default.
• W2001982092 hasConcept C70289976 @default.
• W2001982092 hasConcept C71924100 @default.
• W2001982092 hasConcept C86803240 @default.
• W2001982092 hasConceptScore W2001982092C112705442 @default.
• W2001982092 hasConceptScore W2001982092C126322002 @default.
• W2001982092 hasConceptScore W2001982092C126838900 @default.
• W2001982092 hasConceptScore W2001982092C142724271 @default.
• W2001982092 hasConceptScore W2001982092C143409427 @default.
• W2001982092 hasConceptScore W2001982092C150903083 @default.
• W2001982092 hasConceptScore W2001982092C173622453 @default.
• W2001982092 hasConceptScore W2001982092C178790620 @default.
• W2001982092 hasConceptScore W2001982092C185592680 @default.
• W2001982092 hasConceptScore W2001982092C207001950 @default.
• W2001982092 hasConceptScore W2001982092C2989005 @default.

• next