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• W2001996567 startingPage "7879" @default.
• W2001996567 abstract "We have made sizeable internal deletions within the self-splicing group I intron of Tetrahymena thermophila. Deletions were made in a piecewise manner in order to remove secondary structural elements thought to be extraneous to the catalytic center of the molecule. The resulting deletion mutants retain self-splicing activity, albeit under modified reaction conditions that enhance duplex stability. Considering those portions of the molecule that can be deleted without a loss of catalytic activity, one is left with a catalytic center of approximately 130 nucleotides that is solely responsible for the molecule's activity." @default.
• W2001996567 created "2016-06-24" @default.
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• W2001996567 date "1989-01-01" @default.
• W2001996567 modified "2023-10-12" @default.
• W2001996567 title "Catalytic activity is retained in the<i>Tetrahymena</i>group I intron despite removal of the large extension of element P5" @default.
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• W2001996567 doi "https://doi.org/10.1093/nar/17.19.7879" @default.
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