Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002000767> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2002000767 endingPage "615" @default.
- W2002000767 startingPage "608" @default.
- W2002000767 abstract "The beta spectrin genes each produce two alternate transcripts the longer of which has a approximately 210 amino acid C-terminal extension including a pleckstrin homology (PH) domain and also an uncharacterized membrane binding site. GST constructs including the entire or the N-terminal segment of the beta I sigma II spectrin PH domain bind to crude and extracted brain membranes, to protein free brain lipid and to vesicles containing phosphatidylinositol-4,5-bisphosphate. This PH domain also binds radiolabelled inositol-1,4,5-trisphosphate (IP3) and preincubation with IP3 inhibits binding to extracted brain membranes. We conclude that membrane binding of the beta I sigma II spectrin C-terminal region is by means of a direct interaction between the N-terminal region of the PH domain and membrane lipids and does not require membrane protein. The PH domain of the beta-adrenergic receptor kinase showed different binding properties in every assay employed, showing that different PH domains may have different membrane binding specificity." @default.
- W2002000767 created "2016-06-24" @default.
- W2002000767 creator A5016825542 @default.
- W2002000767 creator A5089967003 @default.
- W2002000767 date "1995-12-01" @default.
- W2002000767 modified "2023-10-15" @default.
- W2002000767 title "The Association of the C-Terminal Region of β1ΣII Spectrin to Brain Membranes Is Mediated by a pH Domain, Does Not Require Membrane Proteins, and Coincides with a Inositol-1,4,5 Trisphosphate Binding Site" @default.
- W2002000767 doi "https://doi.org/10.1006/bbrc.1995.2818" @default.
- W2002000767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7503742" @default.
- W2002000767 hasPublicationYear "1995" @default.
- W2002000767 type Work @default.
- W2002000767 sameAs 2002000767 @default.
- W2002000767 citedByCount "69" @default.
- W2002000767 countsByYear W20020007672012 @default.
- W2002000767 countsByYear W20020007672013 @default.
- W2002000767 countsByYear W20020007672014 @default.
- W2002000767 countsByYear W20020007672015 @default.
- W2002000767 countsByYear W20020007672016 @default.
- W2002000767 countsByYear W20020007672017 @default.
- W2002000767 countsByYear W20020007672018 @default.
- W2002000767 countsByYear W20020007672019 @default.
- W2002000767 countsByYear W20020007672020 @default.
- W2002000767 countsByYear W20020007672022 @default.
- W2002000767 countsByYear W20020007672023 @default.
- W2002000767 crossrefType "journal-article" @default.
- W2002000767 hasAuthorship W2002000767A5016825542 @default.
- W2002000767 hasAuthorship W2002000767A5089967003 @default.
- W2002000767 hasConcept C104317684 @default.
- W2002000767 hasConcept C107824862 @default.
- W2002000767 hasConcept C12554922 @default.
- W2002000767 hasConcept C130316041 @default.
- W2002000767 hasConcept C142669718 @default.
- W2002000767 hasConcept C1491633281 @default.
- W2002000767 hasConcept C170493617 @default.
- W2002000767 hasConcept C182800266 @default.
- W2002000767 hasConcept C184235292 @default.
- W2002000767 hasConcept C185592680 @default.
- W2002000767 hasConcept C2777427919 @default.
- W2002000767 hasConcept C2780610907 @default.
- W2002000767 hasConcept C41625074 @default.
- W2002000767 hasConcept C49658373 @default.
- W2002000767 hasConcept C50244902 @default.
- W2002000767 hasConcept C55493867 @default.
- W2002000767 hasConcept C86803240 @default.
- W2002000767 hasConceptScore W2002000767C104317684 @default.
- W2002000767 hasConceptScore W2002000767C107824862 @default.
- W2002000767 hasConceptScore W2002000767C12554922 @default.
- W2002000767 hasConceptScore W2002000767C130316041 @default.
- W2002000767 hasConceptScore W2002000767C142669718 @default.
- W2002000767 hasConceptScore W2002000767C1491633281 @default.
- W2002000767 hasConceptScore W2002000767C170493617 @default.
- W2002000767 hasConceptScore W2002000767C182800266 @default.
- W2002000767 hasConceptScore W2002000767C184235292 @default.
- W2002000767 hasConceptScore W2002000767C185592680 @default.
- W2002000767 hasConceptScore W2002000767C2777427919 @default.
- W2002000767 hasConceptScore W2002000767C2780610907 @default.
- W2002000767 hasConceptScore W2002000767C41625074 @default.
- W2002000767 hasConceptScore W2002000767C49658373 @default.
- W2002000767 hasConceptScore W2002000767C50244902 @default.
- W2002000767 hasConceptScore W2002000767C55493867 @default.
- W2002000767 hasConceptScore W2002000767C86803240 @default.
- W2002000767 hasIssue "2" @default.
- W2002000767 hasLocation W20020007671 @default.
- W2002000767 hasLocation W20020007672 @default.
- W2002000767 hasOpenAccess W2002000767 @default.
- W2002000767 hasPrimaryLocation W20020007671 @default.
- W2002000767 hasRelatedWork W1996678176 @default.
- W2002000767 hasRelatedWork W2005239190 @default.
- W2002000767 hasRelatedWork W2019945376 @default.
- W2002000767 hasRelatedWork W2060038896 @default.
- W2002000767 hasRelatedWork W2062051274 @default.
- W2002000767 hasRelatedWork W2066547098 @default.
- W2002000767 hasRelatedWork W2104851111 @default.
- W2002000767 hasRelatedWork W2336019741 @default.
- W2002000767 hasRelatedWork W2344642901 @default.
- W2002000767 hasRelatedWork W2416825813 @default.
- W2002000767 hasVolume "217" @default.
- W2002000767 isParatext "false" @default.
- W2002000767 isRetracted "false" @default.
- W2002000767 magId "2002000767" @default.
- W2002000767 workType "article" @default.