FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002000898> ?p ?o ?g. }

• W2002000898 endingPage "1449" @default.
• W2002000898 startingPage "1445" @default.
• W2002000898 abstract "Maps of end-stage renal disease and amounts of angiotensin-converting enzyme inhibitors prescribed in Japan.BackgroundWe recently found regional differences in the incidence of end-stage renal disease (ESRD) in Japan, which is generally ethnically homogeneous, suggesting that factors other than genetic may contribute to the difference. Here, we examined regional differences in the amounts of expenses spent on antihypertensives, especially angiotensin-converting enzyme (ACE) inhibitors, in our search for an explanation.MethodsAnnually, the Japanese Society for Dialysis Therapy reports the numbers of patients entering maintenance dialysis in each prefecture of Japan since 1982. We used the findings for 1995 to 2000 to calculate the annual incidence of ESRD in each of the 11 regions of Japan. In addition, regional differences in annual amounts paid for antihypertensive drugs, presumably corresponding to the amounts used, during the same 6 years, corrected for population, were estimated.ResultsAs in our 1982 to 1998 study, the incidence of ESRD was high in Okinawa, Kyushu, and Shikoku, while low in Hokuriku, Koshinetsu, and Tohoku (P < 0.0001) [one-way repeated measures analysis of variance (ANOVA)]. We found regional differences in the corrected sum paid for total antihypertensive drugs, ACE inhibitors and calcium antagonists. Only ACE inhibitors were negatively correlated with the incidence of ESRD by linear and multiple regression analyses.ConclusionThe renal protective effects of ACE inhibitors have been established by results with animal models of progressive nephropathy and large-scale clinical trials. Our epidemiologic results for Japan as a whole show the same protective effects still more convincingly from a different approach. Maps of end-stage renal disease and amounts of angiotensin-converting enzyme inhibitors prescribed in Japan. We recently found regional differences in the incidence of end-stage renal disease (ESRD) in Japan, which is generally ethnically homogeneous, suggesting that factors other than genetic may contribute to the difference. Here, we examined regional differences in the amounts of expenses spent on antihypertensives, especially angiotensin-converting enzyme (ACE) inhibitors, in our search for an explanation. Annually, the Japanese Society for Dialysis Therapy reports the numbers of patients entering maintenance dialysis in each prefecture of Japan since 1982. We used the findings for 1995 to 2000 to calculate the annual incidence of ESRD in each of the 11 regions of Japan. In addition, regional differences in annual amounts paid for antihypertensive drugs, presumably corresponding to the amounts used, during the same 6 years, corrected for population, were estimated. As in our 1982 to 1998 study, the incidence of ESRD was high in Okinawa, Kyushu, and Shikoku, while low in Hokuriku, Koshinetsu, and Tohoku (P < 0.0001) [one-way repeated measures analysis of variance (ANOVA)]. We found regional differences in the corrected sum paid for total antihypertensive drugs, ACE inhibitors and calcium antagonists. Only ACE inhibitors were negatively correlated with the incidence of ESRD by linear and multiple regression analyses. The renal protective effects of ACE inhibitors have been established by results with animal models of progressive nephropathy and large-scale clinical trials. Our epidemiologic results for Japan as a whole show the same protective effects still more convincingly from a different approach." @default.
• W2002000898 created "2016-06-24" @default.
• W2002000898 creator A5000470887 @default.
• W2002000898 creator A5000563078 @default.
• W2002000898 creator A5020639447 @default.
• W2002000898 creator A5038699745 @default.
• W2002000898 creator A5046509932 @default.
• W2002000898 creator A5055933206 @default.
• W2002000898 creator A5055973656 @default.
• W2002000898 date "2003-10-01" @default.
• W2002000898 modified "2023-09-25" @default.
• W2002000898 title "Maps of end-stage renal disease and amounts of angiotensin-converting enzyme inhibitors prescribed in Japan" @default.
• W2002000898 cites W2031534703 @default.
• W2002000898 cites W2034961623 @default.
• W2002000898 cites W2044773944 @default.
• W2002000898 cites W2087709498 @default.
• W2002000898 cites W2088243155 @default.
• W2002000898 cites W2108807575 @default.
• W2002000898 cites W2136898798 @default.
• W2002000898 cites W2143144750 @default.
• W2002000898 cites W2147804563 @default.
• W2002000898 cites W2157734027 @default.
• W2002000898 cites W2170453602 @default.
• W2002000898 cites W2312400976 @default.
• W2002000898 cites W2318264733 @default.
• W2002000898 cites W2321986725 @default.
• W2002000898 cites W2615684303 @default.
• W2002000898 cites W3022929210 @default.
• W2002000898 cites W3156148333 @default.
• W2002000898 doi "https://doi.org/10.1046/j.1523-1755.2003.00221.x" @default.
• W2002000898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12969164" @default.
• W2002000898 hasPublicationYear "2003" @default.
• W2002000898 type Work @default.
• W2002000898 sameAs 2002000898 @default.
• W2002000898 citedByCount "32" @default.
• W2002000898 countsByYear W20020008982012 @default.
• W2002000898 countsByYear W20020008982013 @default.
• W2002000898 countsByYear W20020008982014 @default.
• W2002000898 countsByYear W20020008982015 @default.
• W2002000898 countsByYear W20020008982018 @default.
• W2002000898 countsByYear W20020008982021 @default.
• W2002000898 countsByYear W20020008982022 @default.
• W2002000898 crossrefType "journal-article" @default.
• W2002000898 hasAuthorship W2002000898A5000470887 @default.
• W2002000898 hasAuthorship W2002000898A5000563078 @default.
• W2002000898 hasAuthorship W2002000898A5020639447 @default.
• W2002000898 hasAuthorship W2002000898A5038699745 @default.
• W2002000898 hasAuthorship W2002000898A5046509932 @default.
• W2002000898 hasAuthorship W2002000898A5055933206 @default.
• W2002000898 hasAuthorship W2002000898A5055973656 @default.
• W2002000898 hasBestOaLocation W20020008981 @default.
• W2002000898 hasConcept C120665830 @default.
• W2002000898 hasConcept C121332964 @default.
• W2002000898 hasConcept C126322002 @default.
• W2002000898 hasConcept C134018914 @default.
• W2002000898 hasConcept C27016395 @default.
• W2002000898 hasConcept C2779134260 @default.
• W2002000898 hasConcept C2779611605 @default.
• W2002000898 hasConcept C2779978075 @default.
• W2002000898 hasConcept C2908647359 @default.
• W2002000898 hasConcept C3019040382 @default.
• W2002000898 hasConcept C61511704 @default.
• W2002000898 hasConcept C66882249 @default.
• W2002000898 hasConcept C71924100 @default.
• W2002000898 hasConcept C84393581 @default.
• W2002000898 hasConcept C97355855 @default.
• W2002000898 hasConcept C99454951 @default.
• W2002000898 hasConceptScore W2002000898C120665830 @default.
• W2002000898 hasConceptScore W2002000898C121332964 @default.
• W2002000898 hasConceptScore W2002000898C126322002 @default.
• W2002000898 hasConceptScore W2002000898C134018914 @default.
• W2002000898 hasConceptScore W2002000898C27016395 @default.
• W2002000898 hasConceptScore W2002000898C2779134260 @default.
• W2002000898 hasConceptScore W2002000898C2779611605 @default.
• W2002000898 hasConceptScore W2002000898C2779978075 @default.
• W2002000898 hasConceptScore W2002000898C2908647359 @default.
• W2002000898 hasConceptScore W2002000898C3019040382 @default.
• W2002000898 hasConceptScore W2002000898C61511704 @default.
• W2002000898 hasConceptScore W2002000898C66882249 @default.
• W2002000898 hasConceptScore W2002000898C71924100 @default.
• W2002000898 hasConceptScore W2002000898C84393581 @default.
• W2002000898 hasConceptScore W2002000898C97355855 @default.
• W2002000898 hasConceptScore W2002000898C99454951 @default.
• W2002000898 hasIssue "4" @default.
• W2002000898 hasLocation W20020008981 @default.
• W2002000898 hasLocation W20020008982 @default.
• W2002000898 hasOpenAccess W2002000898 @default.
• W2002000898 hasPrimaryLocation W20020008981 @default.
• W2002000898 hasRelatedWork W1966732677 @default.
• W2002000898 hasRelatedWork W2004848147 @default.
• W2002000898 hasRelatedWork W2009148223 @default.
• W2002000898 hasRelatedWork W2026875761 @default.
• W2002000898 hasRelatedWork W2072957388 @default.
• W2002000898 hasRelatedWork W2085884179 @default.
• W2002000898 hasRelatedWork W2118991785 @default.
• W2002000898 hasRelatedWork W2596701209 @default.
• W2002000898 hasRelatedWork W2748952813 @default.
• W2002000898 hasRelatedWork W4385563478 @default.

• next