FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002023798> ?p ?o ?g. }

• W2002023798 endingPage "164" @default.
• W2002023798 startingPage "158" @default.
• W2002023798 abstract "Morphological studies have indicated divergent pathways for the endocytosis of epidermal growth factor (EGF) and transferrin (Tf). In order to obtain biochemical evidence for the pathways associated with the endocytosis of EGF and Tf, a series of Percoll density gradients were employed to separate individual cellular components. Subcellular fractionation of murine fibro-blasts exposed to a 2-min pulse of either 125l-Tf or 125I-EGF results in the detection of a total of six cellular compartments related to the internalization process of these ligands. The results of kinetic analysis of the entry of EGF into five membranous fractions is consistent with a model in which ligand is transferred sequentially from the plasma membrane through three distinct prelysosomal environments prior to reaching secondary lysosomes. Each prelysosomal compartment exhibits distinct density and temporal properties in a Percoll density gradient and may represent preexisting endocytic vesicles and/or specific domains of a continuous tubular structure, vesicularized during the process of cell disruption. In addition, the observed differential migration on Percoll density gradients of Tf and EGF containing compartments indicates that the majority of cell bound Tf segregates from EGF and enters a compartment lacking EGF within 5 min of internalization." @default.
• W2002023798 created "2016-06-24" @default.
• W2002023798 creator A5009997679 @default.
• W2002023798 creator A5076206733 @default.
• W2002023798 date "1987-05-01" @default.
• W2002023798 modified "2023-10-14" @default.
• W2002023798 title "Resolution of multiple endosomal compartments associated with the internalization of epidermal growth factor and transferrin" @default.
• W2002023798 cites W1481559242 @default.
• W2002023798 cites W1511952959 @default.
• W2002023798 cites W1526476832 @default.
• W2002023798 cites W1553513611 @default.
• W2002023798 cites W1575369553 @default.
• W2002023798 cites W1589389762 @default.
• W2002023798 cites W1596679547 @default.
• W2002023798 cites W1603151752 @default.
• W2002023798 cites W170240114 @default.
• W2002023798 cites W1967626450 @default.
• W2002023798 cites W1968395750 @default.
• W2002023798 cites W1973902062 @default.
• W2002023798 cites W1983649348 @default.
• W2002023798 cites W1985851452 @default.
• W2002023798 cites W1986807124 @default.
• W2002023798 cites W1987077416 @default.
• W2002023798 cites W1988361400 @default.
• W2002023798 cites W1998795872 @default.
• W2002023798 cites W2006585409 @default.
• W2002023798 cites W2015808496 @default.
• W2002023798 cites W2022022192 @default.
• W2002023798 cites W2024358996 @default.
• W2002023798 cites W2027076158 @default.
• W2002023798 cites W2027978484 @default.
• W2002023798 cites W2029287429 @default.
• W2002023798 cites W2033593445 @default.
• W2002023798 cites W2036229899 @default.
• W2002023798 cites W2050342182 @default.
• W2002023798 cites W2054385006 @default.
• W2002023798 cites W2059496748 @default.
• W2002023798 cites W2079687293 @default.
• W2002023798 cites W2080580789 @default.
• W2002023798 cites W2086271423 @default.
• W2002023798 cites W2092745810 @default.
• W2002023798 cites W2095276157 @default.
• W2002023798 cites W2110408216 @default.
• W2002023798 cites W2122556355 @default.
• W2002023798 cites W2149938812 @default.
• W2002023798 cites W2161106503 @default.
• W2002023798 cites W2163724008 @default.
• W2002023798 cites W2164227469 @default.
• W2002023798 cites W2330436374 @default.
• W2002023798 cites W2417897260 @default.
• W2002023798 cites W4239088562 @default.
• W2002023798 cites W4321429512 @default.
• W2002023798 cites W1969308802 @default.
• W2002023798 doi "https://doi.org/10.1002/jcp.1041310204" @default.
• W2002023798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3495541" @default.
• W2002023798 hasPublicationYear "1987" @default.
• W2002023798 type Work @default.
• W2002023798 sameAs 2002023798 @default.
• W2002023798 citedByCount "19" @default.
• W2002023798 countsByYear W20020237982023 @default.
• W2002023798 crossrefType "journal-article" @default.
• W2002023798 hasAuthorship W2002023798A5009997679 @default.
• W2002023798 hasAuthorship W2002023798A5076206733 @default.
• W2002023798 hasConcept C102747710 @default.
• W2002023798 hasConcept C130316041 @default.
• W2002023798 hasConcept C139770010 @default.
• W2002023798 hasConcept C1491633281 @default.
• W2002023798 hasConcept C168240541 @default.
• W2002023798 hasConcept C170493617 @default.
• W2002023798 hasConcept C202751555 @default.
• W2002023798 hasConcept C22814914 @default.
• W2002023798 hasConcept C27239569 @default.
• W2002023798 hasConcept C2776362946 @default.
• W2002023798 hasConcept C28005876 @default.
• W2002023798 hasConcept C32264632 @default.
• W2002023798 hasConcept C40017333 @default.
• W2002023798 hasConcept C41625074 @default.
• W2002023798 hasConcept C48679268 @default.
• W2002023798 hasConcept C55493867 @default.
• W2002023798 hasConcept C78885561 @default.
• W2002023798 hasConcept C79747257 @default.
• W2002023798 hasConcept C79879829 @default.
• W2002023798 hasConcept C86803240 @default.
• W2002023798 hasConcept C95444343 @default.
• W2002023798 hasConceptScore W2002023798C102747710 @default.
• W2002023798 hasConceptScore W2002023798C130316041 @default.
• W2002023798 hasConceptScore W2002023798C139770010 @default.
• W2002023798 hasConceptScore W2002023798C1491633281 @default.
• W2002023798 hasConceptScore W2002023798C168240541 @default.
• W2002023798 hasConceptScore W2002023798C170493617 @default.
• W2002023798 hasConceptScore W2002023798C202751555 @default.
• W2002023798 hasConceptScore W2002023798C22814914 @default.
• W2002023798 hasConceptScore W2002023798C27239569 @default.
• W2002023798 hasConceptScore W2002023798C2776362946 @default.
• W2002023798 hasConceptScore W2002023798C28005876 @default.
• W2002023798 hasConceptScore W2002023798C32264632 @default.
• W2002023798 hasConceptScore W2002023798C40017333 @default.
• W2002023798 hasConceptScore W2002023798C41625074 @default.

• next