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• W2002033439 abstract "<h3>Objective</h3> To compare the palatability of 3 oral rehydration solutions. <h3>Design</h3> Prospective, blinded, randomized, 3-period, 3-treatment crossover trial. <h3>Setting</h3> Emergency department of a tertiary care pediatric hospital. <h3>Participants</h3> Sixty-six children aged 5 to 10 years with concerns unrelated to the gastrointestinal tract. <h3>Intervention</h3> Each participant consumed as much of each solution as they desired during a 15-minute period. <h3>Main Outcome Measures</h3> The primary outcome was each child's rating of taste as measured on a 100-mm visual analog scale (worst taste, 0 mm; best taste, 100 mm). Secondary outcome measures were volume consumed, willingness to consume each liquid again, and the most favored liquid. <h3>Results</h3> All enrolled patients completed all 3 study periods. A significant carryover effect was detected for taste scores (<i>P</i> = .03), which were significantly different with and without adjustment for the carryover effect (<i>P</i> < .001). Unadjusted values were 65 mm for Pedialyte, 58 mm for Pediatric Electrolyte, and 23 mm for Enfalyte. Differences in mean volume consumed were not significant (Enfalyte, 15 mL; Pediatric Electrolyte, 17 mL; and Pedialyte, 22 mL [<i>P</i> = .44]). The proportion of children who would drink each solution in the future varied significantly between Enfalyte and Pediatric Electrolyte (odds ratio, 0.22; 95% confidence interval, 0.11-0.46) and between Enfalyte and Pedialyte (0.38; 0.25-0.57). There were differences in the identification of the best-tasting solution, with Pedialyte selected by 35 of 66 children (53%), Pediatric Electrolyte by 26 of 66 children (39%), and Enfalyte by 5 of 66 children (8%) (<i>P</i> < .001). <h3>Conclusion</h3> Sucralose-sweetened oral rehydration solutions (Pedialyte and Pediatric Electrolyte) were significantly more palatable than was a comparable rice-based solution (Enfalyte). <h3>Trial Registration</h3> clinicaltrials.gov Identifier:NCT00689312" @default.
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• W2002033439 date "2010-08-01" @default.
• W2002033439 modified "2023-10-17" @default.
• W2002033439 title "Assessing the Palatability of Oral Rehydration Solutions in School-aged Children" @default.
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• W2002033439 doi "https://doi.org/10.1001/archpediatrics.2010.129" @default.
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