FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002033810> ?p ?o ?g. }

• W2002033810 endingPage "412" @default.
• W2002033810 startingPage "403" @default.
• W2002033810 abstract "Beyond the Framingham Stroke Risk Score, prediction of future stroke may improve with a genetic risk score (GRS) based on single-nucleotide polymorphisms associated with stroke and its risk factors.The study includes 4 population-based cohorts with 2047 first incident strokes from 22,720 initially stroke-free European origin participants aged ≥55 years, who were followed for up to 20 years. GRSs were constructed with 324 single-nucleotide polymorphisms implicated in stroke and 9 risk factors. The association of the GRS to first incident stroke was tested using Cox regression; the GRS predictive properties were assessed with area under the curve statistics comparing the GRS with age and sex, Framingham Stroke Risk Score models, and reclassification statistics. These analyses were performed per cohort and in a meta-analysis of pooled data. Replication was sought in a case-control study of ischemic stroke.In the meta-analysis, adding the GRS to the Framingham Stroke Risk Score, age and sex model resulted in a significant improvement in discrimination (all stroke: Δjoint area under the curve=0.016, P=2.3×10(-6); ischemic stroke: Δjoint area under the curve=0.021, P=3.7×10(-7)), although the overall area under the curve remained low. In all the studies, there was a highly significantly improved net reclassification index (P<10(-4)).The single-nucleotide polymorphisms associated with stroke and its risk factors result only in a small improvement in prediction of future stroke compared with the classical epidemiological risk factors for stroke." @default.
• W2002033810 created "2016-06-24" @default.
• W2002033810 creator A5000620030 @default.
• W2002033810 creator A5002821639 @default.
• W2002033810 creator A5003219679 @default.
• W2002033810 creator A5004324001 @default.
• W2002033810 creator A5006663312 @default.
• W2002033810 creator A5010336223 @default.
• W2002033810 creator A5011863508 @default.
• W2002033810 creator A5017009749 @default.
• W2002033810 creator A5018722034 @default.
• W2002033810 creator A5022072512 @default.
• W2002033810 creator A5024226928 @default.
• W2002033810 creator A5027800297 @default.
• W2002033810 creator A5029632441 @default.
• W2002033810 creator A5031530236 @default.
• W2002033810 creator A5035126983 @default.
• W2002033810 creator A5035342009 @default.
• W2002033810 creator A5036370752 @default.
• W2002033810 creator A5039611937 @default.
• W2002033810 creator A5040599069 @default.
• W2002033810 creator A5040770914 @default.
• W2002033810 creator A5041586675 @default.
• W2002033810 creator A5041676520 @default.
• W2002033810 creator A5043015080 @default.
• W2002033810 creator A5043332165 @default.
• W2002033810 creator A5043655881 @default.
• W2002033810 creator A5044048476 @default.
• W2002033810 creator A5053831270 @default.
• W2002033810 creator A5054662814 @default.
• W2002033810 creator A5056145805 @default.
• W2002033810 creator A5056798958 @default.
• W2002033810 creator A5057654443 @default.
• W2002033810 creator A5058678004 @default.
• W2002033810 creator A5061123357 @default.
• W2002033810 creator A5062883630 @default.
• W2002033810 creator A5063851108 @default.
• W2002033810 creator A5064438341 @default.
• W2002033810 creator A5069393328 @default.
• W2002033810 creator A5071606911 @default.
• W2002033810 creator A5071825455 @default.
• W2002033810 creator A5075061959 @default.
• W2002033810 creator A5075741409 @default.
• W2002033810 creator A5077569991 @default.
• W2002033810 creator A5078614126 @default.
• W2002033810 creator A5081896930 @default.
• W2002033810 creator A5088983460 @default.
• W2002033810 date "2014-02-01" @default.
• W2002033810 modified "2023-10-08" @default.
• W2002033810 title "Predicting Stroke Through Genetic Risk Functions" @default.
• W2002033810 cites W1990479835 @default.
• W2002033810 cites W2000081470 @default.
• W2002033810 cites W2009969429 @default.
• W2002033810 cites W2010457736 @default.
• W2002033810 cites W2011877873 @default.
• W2002033810 cites W2015060037 @default.
• W2002033810 cites W2017899376 @default.
• W2002033810 cites W2037233673 @default.
• W2002033810 cites W2054588636 @default.
• W2002033810 cites W2071721045 @default.
• W2002033810 cites W2074945962 @default.
• W2002033810 cites W2095888495 @default.
• W2002033810 cites W2096029390 @default.
• W2002033810 cites W2101605059 @default.
• W2002033810 cites W2102150307 @default.
• W2002033810 cites W2102622802 @default.
• W2002033810 cites W2106421416 @default.
• W2002033810 cites W2111341604 @default.
• W2002033810 cites W2116831158 @default.
• W2002033810 cites W2135954257 @default.
• W2002033810 cites W2152479330 @default.
• W2002033810 cites W2157788171 @default.
• W2002033810 cites W2161197885 @default.
• W2002033810 cites W2163331125 @default.
• W2002033810 cites W2394084479 @default.
• W2002033810 cites W4211231996 @default.
• W2002033810 cites W4242416368 @default.
• W2002033810 doi "https://doi.org/10.1161/strokeaha.113.003044" @default.
• W2002033810 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3955258" @default.
• W2002033810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24436238" @default.
• W2002033810 hasPublicationYear "2014" @default.
• W2002033810 type Work @default.
• W2002033810 sameAs 2002033810 @default.
• W2002033810 citedByCount "61" @default.
• W2002033810 countsByYear W20020338102014 @default.
• W2002033810 countsByYear W20020338102015 @default.
• W2002033810 countsByYear W20020338102016 @default.
• W2002033810 countsByYear W20020338102017 @default.
• W2002033810 countsByYear W20020338102018 @default.
• W2002033810 countsByYear W20020338102019 @default.
• W2002033810 countsByYear W20020338102020 @default.
• W2002033810 countsByYear W20020338102021 @default.
• W2002033810 countsByYear W20020338102022 @default.
• W2002033810 countsByYear W20020338102023 @default.
• W2002033810 crossrefType "journal-article" @default.
• W2002033810 hasAuthorship W2002033810A5000620030 @default.
• W2002033810 hasAuthorship W2002033810A5002821639 @default.
• W2002033810 hasAuthorship W2002033810A5003219679 @default.

• next