FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002044905> ?p ?o ?g. }

• W2002044905 endingPage "266" @default.
• W2002044905 startingPage "260" @default.
• W2002044905 abstract "Neural transplantation holds promise for the treatment of traumatic brain and spinal cord injury by replacing lost cellular elements as well as repairing neural damage. Fetal human stem cells derived from central nervous system (CNS) tissue are potential transplantable sources for all cell types found in the mature human nervous system including neurons, astrocytes and oligodendroglia. Although nearly all areas of the fetal human neuraxis contain undifferentiated neural precursor cells, the phenotypic fate of the daughter cells might vary from one region to another during a specific developmental period. The purpose of this study was to compare the various cell types derived from neural precursors cultured from second trimester fetal human brain and spinal cord. To this end, brains (n = 8) and spinal cords (n = 8) of 15-24 week fetuses were dissociated and grown in culture medium supplemented with epidermal growth factor (EGF), basic fibroblast growth factor (FGF) and leukemia inhibitory factor (LIF). The proliferating precursor cells from both brain and spinal cord grew as spherical masses that were plated on laminin-coated dishes after seven days in culture. During the next 5-7 days, the cells that emerged from these spheres were fixed and processed for immunocytochemistry. Brain derived spheres gave rise to cells expressing antigens specific for neurons (MAP-2ab and neuron specific-intermediate filaments), astrocytes (GFAP) and oligodendrocytes (A007). In contrast, cells that emerged from spinal cord derived spheres were only immunoreactive for GFAP. These data suggest that neuroepithelial precursor cells from different CNS regions, although similar in their responsiveness to proliferative growth factors, might differ in their ability to generate different cell types in the adult CNS." @default.
• W2002044905 created "2016-06-24" @default.
• W2002044905 creator A5020906742 @default.
• W2002044905 creator A5054769603 @default.
• W2002044905 creator A5062156914 @default.
• W2002044905 creator A5069431895 @default.
• W2002044905 date "2001-03-01" @default.
• W2002044905 modified "2023-10-16" @default.
• W2002044905 title "Comparison of neural precursor cell fate in second trimester human brain and spinal cord" @default.
• W2002044905 cites W1483365010 @default.
• W2002044905 cites W1484682139 @default.
• W2002044905 cites W1508792316 @default.
• W2002044905 cites W1733539716 @default.
• W2002044905 cites W1785202197 @default.
• W2002044905 cites W1859089489 @default.
• W2002044905 cites W1963652700 @default.
• W2002044905 cites W1969165581 @default.
• W2002044905 cites W1969854703 @default.
• W2002044905 cites W1979953624 @default.
• W2002044905 cites W1989389324 @default.
• W2002044905 cites W1990213480 @default.
• W2002044905 cites W2020676683 @default.
• W2002044905 cites W2034631388 @default.
• W2002044905 cites W2037840450 @default.
• W2002044905 cites W2042153218 @default.
• W2002044905 cites W2046006021 @default.
• W2002044905 cites W2046450144 @default.
• W2002044905 cites W2059617909 @default.
• W2002044905 cites W2063360834 @default.
• W2002044905 cites W2079356804 @default.
• W2002044905 cites W2085180001 @default.
• W2002044905 cites W2087490798 @default.
• W2002044905 cites W2104977120 @default.
• W2002044905 cites W2113161487 @default.
• W2002044905 cites W2117058176 @default.
• W2002044905 cites W2135713829 @default.
• W2002044905 cites W2139208934 @default.
• W2002044905 cites W2139968664 @default.
• W2002044905 cites W2142481011 @default.
• W2002044905 cites W2158698313 @default.
• W2002044905 cites W2158899368 @default.
• W2002044905 cites W2163643958 @default.
• W2002044905 cites W2164118558 @default.
• W2002044905 cites W4211149619 @default.
• W2002044905 cites W60810139 @default.
• W2002044905 doi "https://doi.org/10.1179/016164101101198406" @default.
• W2002044905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11320606" @default.
• W2002044905 hasPublicationYear "2001" @default.
• W2002044905 type Work @default.
• W2002044905 sameAs 2002044905 @default.
• W2002044905 citedByCount "16" @default.
• W2002044905 countsByYear W20020449052013 @default.
• W2002044905 countsByYear W20020449052014 @default.
• W2002044905 countsByYear W20020449052018 @default.
• W2002044905 crossrefType "journal-article" @default.
• W2002044905 hasAuthorship W2002044905A5020906742 @default.
• W2002044905 hasAuthorship W2002044905A5054769603 @default.
• W2002044905 hasAuthorship W2002044905A5062156914 @default.
• W2002044905 hasAuthorship W2002044905A5069431895 @default.
• W2002044905 hasConcept C124964019 @default.
• W2002044905 hasConcept C134018914 @default.
• W2002044905 hasConcept C136834591 @default.
• W2002044905 hasConcept C142724271 @default.
• W2002044905 hasConcept C1491633281 @default.
• W2002044905 hasConcept C169760540 @default.
• W2002044905 hasConcept C196843134 @default.
• W2002044905 hasConcept C200707615 @default.
• W2002044905 hasConcept C2778794669 @default.
• W2002044905 hasConcept C2780594696 @default.
• W2002044905 hasConcept C2780775167 @default.
• W2002044905 hasConcept C28328180 @default.
• W2002044905 hasConcept C35866371 @default.
• W2002044905 hasConcept C529278444 @default.
• W2002044905 hasConcept C54355233 @default.
• W2002044905 hasConcept C71924100 @default.
• W2002044905 hasConcept C86803240 @default.
• W2002044905 hasConcept C95444343 @default.
• W2002044905 hasConceptScore W2002044905C124964019 @default.
• W2002044905 hasConceptScore W2002044905C134018914 @default.
• W2002044905 hasConceptScore W2002044905C136834591 @default.
• W2002044905 hasConceptScore W2002044905C142724271 @default.
• W2002044905 hasConceptScore W2002044905C1491633281 @default.
• W2002044905 hasConceptScore W2002044905C169760540 @default.
• W2002044905 hasConceptScore W2002044905C196843134 @default.
• W2002044905 hasConceptScore W2002044905C200707615 @default.
• W2002044905 hasConceptScore W2002044905C2778794669 @default.
• W2002044905 hasConceptScore W2002044905C2780594696 @default.
• W2002044905 hasConceptScore W2002044905C2780775167 @default.
• W2002044905 hasConceptScore W2002044905C28328180 @default.
• W2002044905 hasConceptScore W2002044905C35866371 @default.
• W2002044905 hasConceptScore W2002044905C529278444 @default.
• W2002044905 hasConceptScore W2002044905C54355233 @default.
• W2002044905 hasConceptScore W2002044905C71924100 @default.
• W2002044905 hasConceptScore W2002044905C86803240 @default.
• W2002044905 hasConceptScore W2002044905C95444343 @default.
• W2002044905 hasIssue "2-3" @default.
• W2002044905 hasLocation W20020449051 @default.
• W2002044905 hasLocation W20020449052 @default.

• next