FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002051220> ?p ?o ?g. }

• W2002051220 endingPage "95" @default.
• W2002051220 startingPage "83" @default.
• W2002051220 abstract "Chlorinated hydrocarbon insecticides quench the fluorescence of N-alkyl derivatives of carbazole. We used phospholipids with covalently attached carbazole as probes for the interactions of chlorinated hydrocarbon insecticides with lipid bilayers, the object being to understand better the toxicities of chlorinated hydro-carbons. Fluorescence quenching measurements revealed the lipid-water partition coefficients of the chlorinated hydrocarbons, their diffusion coefficients in the membranes, and the binding capacities of the membranes for the chlorinated hydrocarbons. Active insecticides were compared with inactive analogues to test whether activities correlated with chlorinated hydrocarbon-membrane interactions. Thus DDT and methoxychlor were compared with inactive DDE, and insecticidal gamma-lindane was compared with three less active stereoisomers. The partition coefficients, diffusion coefficients and membrane saturation capacities did not correlate with insecticidal potency. The partition coefficients of these chlorinated hydrocarbons were larger in bilayers containing unsaturated fatty acyl chains as compared to bilayers containing saturated fatty acyl chains. Interestingly, neural membranes are known to contain a large percentage of unsaturated lipids. Our results indicate that the activities of chlorinated hydrocarbons are not a result of specific interactions of these compounds with the lipids of membranes. However, the neurotoxicity of chlorinated hydrocarbons may be amplified by selective partitioning in the unsaturated neural membranes." @default.
• W2002051220 created "2016-06-24" @default.
• W2002051220 creator A5070769503 @default.
• W2002051220 creator A5074798370 @default.
• W2002051220 date "1982-01-01" @default.
• W2002051220 modified "2023-10-17" @default.
• W2002051220 title "Interactions of chlorinated hydrocarbon insecticides with membranes" @default.
• W2002051220 cites W1491182318 @default.
• W2002051220 cites W1526385127 @default.
• W2002051220 cites W1821425175 @default.
• W2002051220 cites W1963829691 @default.
• W2002051220 cites W1969184231 @default.
• W2002051220 cites W1979730689 @default.
• W2002051220 cites W1980038935 @default.
• W2002051220 cites W1990254561 @default.
• W2002051220 cites W1991559715 @default.
• W2002051220 cites W1991773380 @default.
• W2002051220 cites W1997521622 @default.
• W2002051220 cites W2001386344 @default.
• W2002051220 cites W2006677924 @default.
• W2002051220 cites W2007363880 @default.
• W2002051220 cites W2012830151 @default.
• W2002051220 cites W2019546500 @default.
• W2002051220 cites W2022668619 @default.
• W2002051220 cites W2024351368 @default.
• W2002051220 cites W2030209357 @default.
• W2002051220 cites W2031157293 @default.
• W2002051220 cites W2038723277 @default.
• W2002051220 cites W2049864926 @default.
• W2002051220 cites W2051441143 @default.
• W2002051220 cites W2061327799 @default.
• W2002051220 cites W2067249830 @default.
• W2002051220 cites W2067468321 @default.
• W2002051220 cites W2073255825 @default.
• W2002051220 cites W2077003674 @default.
• W2002051220 cites W2078192442 @default.
• W2002051220 cites W2078926179 @default.
• W2002051220 cites W2081310315 @default.
• W2002051220 cites W2091153738 @default.
• W2002051220 cites W2092613368 @default.
• W2002051220 cites W2102736268 @default.
• W2002051220 cites W2159916641 @default.
• W2002051220 cites W2200021520 @default.
• W2002051220 cites W2313002083 @default.
• W2002051220 cites W4246432387 @default.
• W2002051220 cites W1976130669 @default.
• W2002051220 doi "https://doi.org/10.1016/0005-2736(82)90052-9" @default.
• W2002051220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7055557" @default.
• W2002051220 hasPublicationYear "1982" @default.
• W2002051220 type Work @default.
• W2002051220 sameAs 2002051220 @default.
• W2002051220 citedByCount "81" @default.
• W2002051220 countsByYear W20020512202013 @default.
• W2002051220 countsByYear W20020512202015 @default.
• W2002051220 countsByYear W20020512202020 @default.
• W2002051220 countsByYear W20020512202022 @default.
• W2002051220 crossrefType "journal-article" @default.
• W2002051220 hasAuthorship W2002051220A5070769503 @default.
• W2002051220 hasAuthorship W2002051220A5074798370 @default.
• W2002051220 hasConcept C161176658 @default.
• W2002051220 hasConcept C178790620 @default.
• W2002051220 hasConcept C185592680 @default.
• W2002051220 hasConcept C192552737 @default.
• W2002051220 hasConcept C2776127813 @default.
• W2002051220 hasConcept C2777207669 @default.
• W2002051220 hasConcept C2778918659 @default.
• W2002051220 hasConcept C2780263894 @default.
• W2002051220 hasConcept C2780509179 @default.
• W2002051220 hasConcept C41625074 @default.
• W2002051220 hasConcept C55493867 @default.
• W2002051220 hasConcept C6557445 @default.
• W2002051220 hasConcept C86803240 @default.
• W2002051220 hasConceptScore W2002051220C161176658 @default.
• W2002051220 hasConceptScore W2002051220C178790620 @default.
• W2002051220 hasConceptScore W2002051220C185592680 @default.
• W2002051220 hasConceptScore W2002051220C192552737 @default.
• W2002051220 hasConceptScore W2002051220C2776127813 @default.
• W2002051220 hasConceptScore W2002051220C2777207669 @default.
• W2002051220 hasConceptScore W2002051220C2778918659 @default.
• W2002051220 hasConceptScore W2002051220C2780263894 @default.
• W2002051220 hasConceptScore W2002051220C2780509179 @default.
• W2002051220 hasConceptScore W2002051220C41625074 @default.
• W2002051220 hasConceptScore W2002051220C55493867 @default.
• W2002051220 hasConceptScore W2002051220C6557445 @default.
• W2002051220 hasConceptScore W2002051220C86803240 @default.
• W2002051220 hasIssue "1" @default.
• W2002051220 hasLocation W20020512201 @default.
• W2002051220 hasLocation W20020512202 @default.
• W2002051220 hasOpenAccess W2002051220 @default.
• W2002051220 hasPrimaryLocation W20020512201 @default.
• W2002051220 hasRelatedWork W1981004562 @default.
• W2002051220 hasRelatedWork W2002051220 @default.
• W2002051220 hasRelatedWork W2086124779 @default.
• W2002051220 hasRelatedWork W2087459840 @default.
• W2002051220 hasRelatedWork W2107641298 @default.
• W2002051220 hasRelatedWork W2320033002 @default.
• W2002051220 hasRelatedWork W2395452842 @default.
• W2002051220 hasRelatedWork W2396758130 @default.

• next