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• W2002055798 abstract "Objective: To determine whether a history of depression and/or posttraumatic stress disorder (PTSD) is associated with all-cause mortality in primary care patients over an average of 2 years. Methods: Patients from seven Department of Veterans Affairs medical centers completed mailed questionnaires. Depression and PTSD status were determined from patient self-report of a prior diagnosis and/or electronic administrative data. Date of death was ascertained from Veterans Health Information Systems and Technology Architecture and the Department of Veterans Affairs' Beneficiary Identification and Records Locator System. Results: Among 35,715 primary care patients, those with a history of depression without a history of PTSD (n = 6876) were at increased risk of death over an average of 2 years compared with patients with neither depression nor PTSD after adjustment for demographic variables, health behaviors, and medical comorbidity (hazard ratio (HR) = 1.17; 95% Confidence Interval (CI) = 1.06–1.28). However, patients with a history of PTSD without a history of depression (n = 748) were not at increased risk of death compared with patients with neither depression nor PTSD (HR = 0.84; 95% CI = 0.63–1.13). Patients with a history of both (n = 3762) were at increased risk of death after adjustment for demographic factors, although not after additional adjustment for health behaviors and medical comorbidity (HR = 0.90; 95% CI = 0.78–1.04). Conclusions: In a large sample of veterans, a prior diagnosis of depression, but not PTSD, was associated with an increased risk of death over an average of 2 years after adjusting for age, demographic variables, health behaviors, and medical comorbidity. PTSD = posttraumatic stress disorder; VA= Department of Veterans Affairs; ACQUIP = Ambulatory Care Quality Improvement Project; MHI-5 = Mental Health Inventory; CHF = congestive heart failure; MI = heart attack/myocardial infarction." @default.
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• W2002055798 date "2008-01-01" @default.
• W2002055798 modified "2023-10-02" @default.
• W2002055798 title "Depression, Posttraumatic Stress Disorder, and Mortality" @default.
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• W2002055798 doi "https://doi.org/10.1097/psy.0b013e31815aac93" @default.
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