FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002069416> ?p ?o ?g. }

• W2002069416 endingPage "192" @default.
• W2002069416 startingPage "185" @default.
• W2002069416 abstract "Elevated 23Na MR image intensity after acute myocardial infarction has previously been shown to correspond to high tissue [Na+] and loss of myocardial viability. In this study, we explored the potential of in vivo 23Na MRI to assess infarct size and investigated possible mechanisms for elevated 23Na image intensity.Thirteen dogs and 8 rabbits underwent in situ coronary artery occlusion and reperfusion and were imaged by 23Na MRI. For anatomically matched left ventricular short-axis cross sections (n=46), infarct size measured by in vivo 23Na MRI correlated well with triphenyltetrazolium chloride staining (r=0.87, y=0.92x+3.37, P<0.001). Elevated 23Na image intensity was observed in infarcted myocardium (206+/-37% of remote in dogs, P<0.001; 215+/-58% in rabbits, P<0.002) but was not observed after severe but reversible ischemic injury (101+/-11% of baseline, P=NS). High-resolution ex vivo imaging revealed that regions of elevated 23Na image intensity appeared to be identical to those of infarcted regions (r=0.97, y=0.92x+1.52, P<0.001). In infarcted regions, total tissue [Na+] was elevated (89+/-12 versus 37+/-9 mmol/L in control tissue, 156+/-60% increase, P<0.001) and was associated with increased intracellular sodium (254+/-68% of control, P<0.005) and an increased intracellular sodium/potassium ratio (868+/-512% of control, P<0.002). Morphometric analysis demonstrated only a minor increase in extracellular volume (17+/-8% versus 14+/-5%, P<0.05) in the infarcted territory.Elevated 23Na MR image intensity in vivo measures infarct size after reperfused infarction in both a large and a small animal model. The mechanism of elevated 23Na image intensity is probably intracellular sodium accumulation secondary to loss of myocyte ionic homeostasis." @default.
• W2002069416 created "2016-06-24" @default.
• W2002069416 creator A5003321014 @default.
• W2002069416 creator A5023888915 @default.
• W2002069416 creator A5038689387 @default.
• W2002069416 creator A5043592365 @default.
• W2002069416 creator A5076169239 @default.
• W2002069416 creator A5079483150 @default.
• W2002069416 date "1999-07-13" @default.
• W2002069416 modified "2023-09-24" @default.
• W2002069416 title "Relationship of Elevated ²³ Na Magnetic Resonance Image Intensity to Infarct Size After Acute Reperfused Myocardial Infarction" @default.
• W2002069416 cites W1972550937 @default.
• W2002069416 cites W1985300575 @default.
• W2002069416 cites W1991117742 @default.
• W2002069416 cites W1999834276 @default.
• W2002069416 cites W2021037687 @default.
• W2002069416 cites W2070951720 @default.
• W2002069416 cites W2090150484 @default.
• W2002069416 cites W2091051297 @default.
• W2002069416 cites W2098699717 @default.
• W2002069416 cites W2117044841 @default.
• W2002069416 cites W2126478397 @default.
• W2002069416 cites W2140233303 @default.
• W2002069416 cites W2151751945 @default.
• W2002069416 cites W2416002725 @default.
• W2002069416 cites W2764766395 @default.
• W2002069416 cites W2973101225 @default.
• W2002069416 cites W4302355088 @default.
• W2002069416 doi "https://doi.org/10.1161/01.cir.100.2.185" @default.
• W2002069416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10402449" @default.
• W2002069416 hasPublicationYear "1999" @default.
• W2002069416 type Work @default.
• W2002069416 sameAs 2002069416 @default.
• W2002069416 citedByCount "119" @default.
• W2002069416 countsByYear W20020694162012 @default.
• W2002069416 countsByYear W20020694162013 @default.
• W2002069416 countsByYear W20020694162014 @default.
• W2002069416 countsByYear W20020694162015 @default.
• W2002069416 countsByYear W20020694162016 @default.
• W2002069416 countsByYear W20020694162017 @default.
• W2002069416 countsByYear W20020694162018 @default.
• W2002069416 countsByYear W20020694162019 @default.
• W2002069416 countsByYear W20020694162020 @default.
• W2002069416 countsByYear W20020694162021 @default.
• W2002069416 countsByYear W20020694162022 @default.
• W2002069416 crossrefType "journal-article" @default.
• W2002069416 hasAuthorship W2002069416A5003321014 @default.
• W2002069416 hasAuthorship W2002069416A5023888915 @default.
• W2002069416 hasAuthorship W2002069416A5038689387 @default.
• W2002069416 hasAuthorship W2002069416A5043592365 @default.
• W2002069416 hasAuthorship W2002069416A5076169239 @default.
• W2002069416 hasAuthorship W2002069416A5079483150 @default.
• W2002069416 hasBestOaLocation W20020694161 @default.
• W2002069416 hasConcept C121332964 @default.
• W2002069416 hasConcept C126322002 @default.
• W2002069416 hasConcept C126838900 @default.
• W2002069416 hasConcept C142724271 @default.
• W2002069416 hasConcept C143409427 @default.
• W2002069416 hasConcept C150903083 @default.
• W2002069416 hasConcept C164705383 @default.
• W2002069416 hasConcept C178790620 @default.
• W2002069416 hasConcept C185592680 @default.
• W2002069416 hasConcept C207001950 @default.
• W2002069416 hasConcept C26291073 @default.
• W2002069416 hasConcept C2776894844 @default.
• W2002069416 hasConcept C2777798775 @default.
• W2002069416 hasConcept C28406088 @default.
• W2002069416 hasConcept C2989005 @default.
• W2002069416 hasConcept C500558357 @default.
• W2002069416 hasConcept C537181965 @default.
• W2002069416 hasConcept C55493867 @default.
• W2002069416 hasConcept C62520636 @default.
• W2002069416 hasConcept C71924100 @default.
• W2002069416 hasConcept C86803240 @default.
• W2002069416 hasConcept C93038891 @default.
• W2002069416 hasConceptScore W2002069416C121332964 @default.
• W2002069416 hasConceptScore W2002069416C126322002 @default.
• W2002069416 hasConceptScore W2002069416C126838900 @default.
• W2002069416 hasConceptScore W2002069416C142724271 @default.
• W2002069416 hasConceptScore W2002069416C143409427 @default.
• W2002069416 hasConceptScore W2002069416C150903083 @default.
• W2002069416 hasConceptScore W2002069416C164705383 @default.
• W2002069416 hasConceptScore W2002069416C178790620 @default.
• W2002069416 hasConceptScore W2002069416C185592680 @default.
• W2002069416 hasConceptScore W2002069416C207001950 @default.
• W2002069416 hasConceptScore W2002069416C26291073 @default.
• W2002069416 hasConceptScore W2002069416C2776894844 @default.
• W2002069416 hasConceptScore W2002069416C2777798775 @default.
• W2002069416 hasConceptScore W2002069416C28406088 @default.
• W2002069416 hasConceptScore W2002069416C2989005 @default.
• W2002069416 hasConceptScore W2002069416C500558357 @default.
• W2002069416 hasConceptScore W2002069416C537181965 @default.
• W2002069416 hasConceptScore W2002069416C55493867 @default.
• W2002069416 hasConceptScore W2002069416C62520636 @default.
• W2002069416 hasConceptScore W2002069416C71924100 @default.
• W2002069416 hasConceptScore W2002069416C86803240 @default.
• W2002069416 hasConceptScore W2002069416C93038891 @default.
• W2002069416 hasIssue "2" @default.

• next