FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002074878> ?p ?o ?g. }

• W2002074878 endingPage "448" @default.
• W2002074878 startingPage "438" @default.
• W2002074878 abstract "We investigated effects of extracellular ATP on intracellular chloride activities ([Cl-]i) and possible contribution of the Cl--HCO3- exchange to this increase in [Cl-]i in isolated guinea pig ventricular muscles. The [Cl-]i and intracellular pH (pHi) were recorded in quiescent ventricular muscles using double-barreled ion-selective microelectrode techniques. MgATP at a concentration higher than 0.1 mM, induced an increase in [Cl-]i, and this increase in [Cl-]i was dependent on the concentration of ATP but not on the concentration of magnesium ions present in the perfusion solution. NaADP, but not NaAMP, at a concentration of 0.5 mM induced a similar increase in [Cl-]i as that induced by MgATP. However, the NaADP-induced increase in [Cl-]i was transient and gradually returned to the control level even though NaADP was continuously present. Furthermore, ATP also triggered a transient acidification of pHi, and both increases in [Cl-]i and intracellular H+ induced by ATP were prevented when preparations were pretreated with stilbene derivatives, SITS and DIDS, or perfused with a Cl--free solution. Our findings showed that the increased extracellular ATP concentrations might trigger an increase in [Cl-]i in ventricular muscles. In light of previous studies showing that cardiac ischemia induced increases in extracellular nucleotide concentrations and [Cl-]i in ventricular muscles, we propose that ischemia-induced accumulation of ATP concentration in the extracellular space may be an important factor to trigger increment of [Cl-]i during ischemic conditions." @default.
• W2002074878 created "2016-06-24" @default.
• W2002074878 creator A5051704695 @default.
• W2002074878 creator A5062672529 @default.
• W2002074878 date "2000-01-01" @default.
• W2002074878 modified "2023-09-25" @default.
• W2002074878 title "Enhancement of Intracellular Cl Concentrations Induced by Extracellular ATP in Guinea Pig Ventricular Muscle" @default.
• W2002074878 cites W1524430041 @default.
• W2002074878 cites W1947888345 @default.
• W2002074878 cites W1969849820 @default.
• W2002074878 cites W1971287143 @default.
• W2002074878 cites W1976785884 @default.
• W2002074878 cites W1976836106 @default.
• W2002074878 cites W1977020147 @default.
• W2002074878 cites W1978987833 @default.
• W2002074878 cites W1985859138 @default.
• W2002074878 cites W1987051971 @default.
• W2002074878 cites W1987812611 @default.
• W2002074878 cites W1991639569 @default.
• W2002074878 cites W2000989410 @default.
• W2002074878 cites W2009935511 @default.
• W2002074878 cites W2012735842 @default.
• W2002074878 cites W2018235445 @default.
• W2002074878 cites W2023131332 @default.
• W2002074878 cites W2025954344 @default.
• W2002074878 cites W2027616380 @default.
• W2002074878 cites W2042573064 @default.
• W2002074878 cites W2052071375 @default.
• W2002074878 cites W2059105096 @default.
• W2002074878 cites W2061880643 @default.
• W2002074878 cites W2063703812 @default.
• W2002074878 cites W2067126238 @default.
• W2002074878 cites W2068991671 @default.
• W2002074878 cites W2095384133 @default.
• W2002074878 cites W2100238828 @default.
• W2002074878 cites W2109416407 @default.
• W2002074878 cites W2113012318 @default.
• W2002074878 cites W2141979997 @default.
• W2002074878 cites W2151763078 @default.
• W2002074878 cites W2156828622 @default.
• W2002074878 cites W2159763620 @default.
• W2002074878 cites W2164404600 @default.
• W2002074878 cites W2167582289 @default.
• W2002074878 cites W2170353863 @default.
• W2002074878 cites W2171031510 @default.
• W2002074878 cites W2222089302 @default.
• W2002074878 cites W2244731059 @default.
• W2002074878 cites W2339512094 @default.
• W2002074878 cites W2346814112 @default.
• W2002074878 cites W2404609735 @default.
• W2002074878 cites W2405557463 @default.
• W2002074878 cites W2415742514 @default.
• W2002074878 cites W2417366532 @default.
• W2002074878 cites W2417835997 @default.
• W2002074878 cites W2420946172 @default.
• W2002074878 cites W2466303878 @default.
• W2002074878 cites W2468423859 @default.
• W2002074878 cites W3018022636 @default.
• W2002074878 doi "https://doi.org/10.1254/jjp.84.438" @default.
• W2002074878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11202617" @default.
• W2002074878 hasPublicationYear "2000" @default.
• W2002074878 type Work @default.
• W2002074878 sameAs 2002074878 @default.
• W2002074878 citedByCount "4" @default.
• W2002074878 countsByYear W20020748782013 @default.
• W2002074878 countsByYear W20020748782014 @default.
• W2002074878 crossrefType "journal-article" @default.
• W2002074878 hasAuthorship W2002074878A5051704695 @default.
• W2002074878 hasAuthorship W2002074878A5062672529 @default.
• W2002074878 hasBestOaLocation W20020748781 @default.
• W2002074878 hasConcept C12554922 @default.
• W2002074878 hasConcept C134018914 @default.
• W2002074878 hasConcept C134897140 @default.
• W2002074878 hasConcept C178790620 @default.
• W2002074878 hasConcept C185592680 @default.
• W2002074878 hasConcept C2778695967 @default.
• W2002074878 hasConcept C2778815084 @default.
• W2002074878 hasConcept C2779533339 @default.
• W2002074878 hasConcept C28406088 @default.
• W2002074878 hasConcept C41625074 @default.
• W2002074878 hasConcept C55493867 @default.
• W2002074878 hasConcept C79879829 @default.
• W2002074878 hasConcept C86803240 @default.
• W2002074878 hasConceptScore W2002074878C12554922 @default.
• W2002074878 hasConceptScore W2002074878C134018914 @default.
• W2002074878 hasConceptScore W2002074878C134897140 @default.
• W2002074878 hasConceptScore W2002074878C178790620 @default.
• W2002074878 hasConceptScore W2002074878C185592680 @default.
• W2002074878 hasConceptScore W2002074878C2778695967 @default.
• W2002074878 hasConceptScore W2002074878C2778815084 @default.
• W2002074878 hasConceptScore W2002074878C2779533339 @default.
• W2002074878 hasConceptScore W2002074878C28406088 @default.
• W2002074878 hasConceptScore W2002074878C41625074 @default.
• W2002074878 hasConceptScore W2002074878C55493867 @default.
• W2002074878 hasConceptScore W2002074878C79879829 @default.
• W2002074878 hasConceptScore W2002074878C86803240 @default.
• W2002074878 hasIssue "4" @default.
• W2002074878 hasLocation W20020748781 @default.

• next