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• W2002076420 abstract "Metabolic chiral inversion of 2-arylpropanoic acids (2-APAs; ‘profens’), such as ibuprofen, is important for pharmacological activity. Several 2-APA-CoA esters were good racemisation substrates for human AMACR 1A, suggesting a common chiral inversion pathway for all 2-APAs and an additional mechanism for their anti-cancer properties." @default.
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• W2002076420 date "2011-01-01" @default.
• W2002076420 modified "2023-10-16" @default.
• W2002076420 title "Chiral inversion of 2-arylpropionyl-CoA esters by human α-methylacyl-CoA racemase 1A (P504S)—a potential mechanism for the anti-cancer effects of ibuprofen" @default.
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• W2002076420 doi "https://doi.org/10.1039/c1cc10763a" @default.
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