FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002076968> ?p ?o ?g. }

• W2002076968 endingPage "580" @default.
• W2002076968 startingPage "575" @default.
• W2002076968 abstract "microRNAs (miRNAs) have been reported to play an essential role in the regulation of brown adipocyte adipogenesis. In the present study, we investigated the role of the miR-106b-93 cluster in the differentiation of brown adipocytes. We found that knockdown of miR-106b and miR-93 significantly induced the expression of brown fat-specific genes and promoted the accumulation of lipid-droplet in differentiating brown adipocytes. In addition, ectopic expression of miR-106b and miR-93 suppressed the mRNA level of Ucp1, a selective hallmark of brown adipocytes. Furthermore, the expression levels of miR-106b and miR-93 are higher in brown adipose tissues of high fat diet-induced obese mice compared to control mice. Taken together, our results identify miR-106b and miR-93 as negative regulators of brown adipocyte differentiation and the miR-106b-93 cluster may play an important role in regulating energy homeostasis." @default.
• W2002076968 created "2016-06-24" @default.
• W2002076968 creator A5001462210 @default.
• W2002076968 creator A5003043493 @default.
• W2002076968 creator A5003688182 @default.
• W2002076968 creator A5026241533 @default.
• W2002076968 creator A5060470951 @default.
• W2002076968 creator A5067825481 @default.
• W2002076968 creator A5069756943 @default.
• W2002076968 creator A5079030810 @default.
• W2002076968 date "2013-09-01" @default.
• W2002076968 modified "2023-10-16" @default.
• W2002076968 title "Identification of miR-106b-93 as a negative regulator of brown adipocyte differentiation" @default.
• W2002076968 cites W144423133 @default.
• W2002076968 cites W1970685293 @default.
• W2002076968 cites W1973859136 @default.
• W2002076968 cites W1982752738 @default.
• W2002076968 cites W1987597166 @default.
• W2002076968 cites W1988183203 @default.
• W2002076968 cites W1995253518 @default.
• W2002076968 cites W1996039273 @default.
• W2002076968 cites W1997196734 @default.
• W2002076968 cites W1999649641 @default.
• W2002076968 cites W2033834901 @default.
• W2002076968 cites W2047982128 @default.
• W2002076968 cites W2050132057 @default.
• W2002076968 cites W2051583212 @default.
• W2002076968 cites W2055928731 @default.
• W2002076968 cites W2058009015 @default.
• W2002076968 cites W2070172494 @default.
• W2002076968 cites W2089747726 @default.
• W2002076968 cites W2096842458 @default.
• W2002076968 cites W2132358997 @default.
• W2002076968 cites W2133009318 @default.
• W2002076968 cites W2168813512 @default.
• W2002076968 cites W2171716790 @default.
• W2002076968 doi "https://doi.org/10.1016/j.bbrc.2013.08.016" @default.
• W2002076968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23954633" @default.
• W2002076968 hasPublicationYear "2013" @default.
• W2002076968 type Work @default.
• W2002076968 sameAs 2002076968 @default.
• W2002076968 citedByCount "51" @default.
• W2002076968 countsByYear W20020769682014 @default.
• W2002076968 countsByYear W20020769682015 @default.
• W2002076968 countsByYear W20020769682016 @default.
• W2002076968 countsByYear W20020769682017 @default.
• W2002076968 countsByYear W20020769682018 @default.
• W2002076968 countsByYear W20020769682019 @default.
• W2002076968 countsByYear W20020769682020 @default.
• W2002076968 countsByYear W20020769682021 @default.
• W2002076968 countsByYear W20020769682022 @default.
• W2002076968 countsByYear W20020769682023 @default.
• W2002076968 crossrefType "journal-article" @default.
• W2002076968 hasAuthorship W2002076968A5001462210 @default.
• W2002076968 hasAuthorship W2002076968A5003043493 @default.
• W2002076968 hasAuthorship W2002076968A5003688182 @default.
• W2002076968 hasAuthorship W2002076968A5026241533 @default.
• W2002076968 hasAuthorship W2002076968A5060470951 @default.
• W2002076968 hasAuthorship W2002076968A5067825481 @default.
• W2002076968 hasAuthorship W2002076968A5069756943 @default.
• W2002076968 hasAuthorship W2002076968A5079030810 @default.
• W2002076968 hasConcept C104317684 @default.
• W2002076968 hasConcept C122927707 @default.
• W2002076968 hasConcept C126322002 @default.
• W2002076968 hasConcept C134018914 @default.
• W2002076968 hasConcept C145059251 @default.
• W2002076968 hasConcept C151279926 @default.
• W2002076968 hasConcept C171089720 @default.
• W2002076968 hasConcept C173396325 @default.
• W2002076968 hasConcept C2776175234 @default.
• W2002076968 hasConcept C2780642333 @default.
• W2002076968 hasConcept C55493867 @default.
• W2002076968 hasConcept C6929976 @default.
• W2002076968 hasConcept C71924100 @default.
• W2002076968 hasConcept C86803240 @default.
• W2002076968 hasConcept C95444343 @default.
• W2002076968 hasConcept C97037327 @default.
• W2002076968 hasConceptScore W2002076968C104317684 @default.
• W2002076968 hasConceptScore W2002076968C122927707 @default.
• W2002076968 hasConceptScore W2002076968C126322002 @default.
• W2002076968 hasConceptScore W2002076968C134018914 @default.
• W2002076968 hasConceptScore W2002076968C145059251 @default.
• W2002076968 hasConceptScore W2002076968C151279926 @default.
• W2002076968 hasConceptScore W2002076968C171089720 @default.
• W2002076968 hasConceptScore W2002076968C173396325 @default.
• W2002076968 hasConceptScore W2002076968C2776175234 @default.
• W2002076968 hasConceptScore W2002076968C2780642333 @default.
• W2002076968 hasConceptScore W2002076968C55493867 @default.
• W2002076968 hasConceptScore W2002076968C6929976 @default.
• W2002076968 hasConceptScore W2002076968C71924100 @default.
• W2002076968 hasConceptScore W2002076968C86803240 @default.
• W2002076968 hasConceptScore W2002076968C95444343 @default.
• W2002076968 hasConceptScore W2002076968C97037327 @default.
• W2002076968 hasFunder F4320321001 @default.
• W2002076968 hasIssue "4" @default.
• W2002076968 hasLocation W20020769681 @default.
• W2002076968 hasLocation W20020769682 @default.
• W2002076968 hasOpenAccess W2002076968 @default.

• next