FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2002077518> ?p ?o ?g. }

• W2002077518 endingPage "175" @default.
• W2002077518 startingPage "167" @default.
• W2002077518 abstract "Abstract Objective The safety, efficacy, and morbidity of radiosurgery (RS) must be established before it can be offered as an alternative to open surgery for unilateral mesial temporal lobe epilepsy. We report the 3‐year outcomes of a multicenter, prospective pilot study of RS. Methods RS was randomized to 20 or 24Gy targeting the amygdala, hippocampus, and parahippocampal gyrus. Seizure diaries evaluated the final seizure remission between months 24 and 36. Verbal memory was evaluated at baseline and 24m with the Wechsler Memory Scale–Revised (WMS‐R) and California Verbal Learning Test (CVLT). Patients were classified as having “significant improvement,” “no change,” and “significant impairment” based on relative change indices. Results Thirteen high‐dose and 17 low‐dose patients were treated. Both groups showed significant reductions in seizures by 1 year after treatment. At the 36‐month follow‐up evaluation, 67% of patients were free of seizures for the prior 12 months (high dose: 10/13, 76.9%; low dose: 10/17, 58.8%). Use of steroids, headaches, and visual field defects did not differ by dose or seizure remission. The prevalence of verbal memory impairment was 15% (4/26 patients); none declined on more than one measure. The prevalence of significant verbal memory improvements was 12% (3/26). Interpretation RS for unilateral mesial temporal lobe epilepsy offers seizure remission rates comparable with those reported previously for open surgery. There were no major safety concerns with high‐dose RS compared with low‐dose RS. Additional research is required to determine whether RS may be a treatment option for some patients with mesial temporal lobe epilepsy. Ann Neurol 2009" @default.
• W2002077518 created "2016-06-24" @default.
• W2002077518 creator A5008597138 @default.
• W2002077518 creator A5014510616 @default.
• W2002077518 creator A5015650055 @default.
• W2002077518 creator A5020032572 @default.
• W2002077518 creator A5025025895 @default.
• W2002077518 creator A5032709669 @default.
• W2002077518 creator A5034100976 @default.
• W2002077518 creator A5041027677 @default.
• W2002077518 creator A5042076336 @default.
• W2002077518 creator A5046287975 @default.
• W2002077518 creator A5052100134 @default.
• W2002077518 creator A5057943090 @default.
• W2002077518 creator A5059057763 @default.
• W2002077518 creator A5061018141 @default.
• W2002077518 creator A5067067307 @default.
• W2002077518 creator A5075819823 @default.
• W2002077518 creator A5086296477 @default.
• W2002077518 creator A5091264881 @default.
• W2002077518 date "2009-02-01" @default.
• W2002077518 modified "2023-10-17" @default.
• W2002077518 title "A multicenter, prospective pilot study of gamma knife radiosurgery for mesial temporal lobe epilepsy: Seizure response, adverse events, and verbal memory" @default.
• W2002077518 cites W1538698005 @default.
• W2002077518 cites W1966100057 @default.
• W2002077518 cites W1967096335 @default.
• W2002077518 cites W1968877963 @default.
• W2002077518 cites W1973634238 @default.
• W2002077518 cites W1975181723 @default.
• W2002077518 cites W1975564074 @default.
• W2002077518 cites W1979808630 @default.
• W2002077518 cites W1980051064 @default.
• W2002077518 cites W1984134627 @default.
• W2002077518 cites W1987584839 @default.
• W2002077518 cites W1987686727 @default.
• W2002077518 cites W2025806411 @default.
• W2002077518 cites W2029567348 @default.
• W2002077518 cites W2037335456 @default.
• W2002077518 cites W2044931971 @default.
• W2002077518 cites W2050943522 @default.
• W2002077518 cites W2052144086 @default.
• W2002077518 cites W2052770597 @default.
• W2002077518 cites W2053063947 @default.
• W2002077518 cites W2055388139 @default.
• W2002077518 cites W2057281409 @default.
• W2002077518 cites W2067460884 @default.
• W2002077518 cites W2077813963 @default.
• W2002077518 cites W2079758805 @default.
• W2002077518 cites W2084257045 @default.
• W2002077518 cites W2086241055 @default.
• W2002077518 cites W2087095134 @default.
• W2002077518 cites W2089163906 @default.
• W2002077518 cites W2089379828 @default.
• W2002077518 cites W2093287528 @default.
• W2002077518 cites W2094753049 @default.
• W2002077518 cites W2096384638 @default.
• W2002077518 cites W2097764649 @default.
• W2002077518 cites W2099822535 @default.
• W2002077518 cites W2102582788 @default.
• W2002077518 cites W2109808616 @default.
• W2002077518 cites W2116191988 @default.
• W2002077518 cites W2122817080 @default.
• W2002077518 cites W2123383271 @default.
• W2002077518 cites W2124878314 @default.
• W2002077518 cites W2157405811 @default.
• W2002077518 cites W2167472217 @default.
• W2002077518 cites W2317495993 @default.
• W2002077518 cites W3211179584 @default.
• W2002077518 cites W4246817163 @default.
• W2002077518 cites W4251744762 @default.
• W2002077518 doi "https://doi.org/10.1002/ana.21558" @default.
• W2002077518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19243009" @default.
• W2002077518 hasPublicationYear "2009" @default.
• W2002077518 type Work @default.
• W2002077518 sameAs 2002077518 @default.
• W2002077518 citedByCount "161" @default.
• W2002077518 countsByYear W20020775182012 @default.
• W2002077518 countsByYear W20020775182013 @default.
• W2002077518 countsByYear W20020775182014 @default.
• W2002077518 countsByYear W20020775182015 @default.
• W2002077518 countsByYear W20020775182016 @default.
• W2002077518 countsByYear W20020775182017 @default.
• W2002077518 countsByYear W20020775182018 @default.
• W2002077518 countsByYear W20020775182019 @default.
• W2002077518 countsByYear W20020775182020 @default.
• W2002077518 countsByYear W20020775182021 @default.
• W2002077518 countsByYear W20020775182022 @default.
• W2002077518 countsByYear W20020775182023 @default.
• W2002077518 crossrefType "journal-article" @default.
• W2002077518 hasAuthorship W2002077518A5008597138 @default.
• W2002077518 hasAuthorship W2002077518A5014510616 @default.
• W2002077518 hasAuthorship W2002077518A5015650055 @default.
• W2002077518 hasAuthorship W2002077518A5020032572 @default.
• W2002077518 hasAuthorship W2002077518A5025025895 @default.
• W2002077518 hasAuthorship W2002077518A5032709669 @default.
• W2002077518 hasAuthorship W2002077518A5034100976 @default.
• W2002077518 hasAuthorship W2002077518A5041027677 @default.
• W2002077518 hasAuthorship W2002077518A5042076336 @default.

• next