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- W2002080188 abstract "Eight male patients who had suffered severe trauma were longitudinally monitored for serum zinc, total protein, alkaline phosphatase and urea nitrogen. Daily urinary zinc and creatinine excretion were also measured. The trauma patients were followed from less than 24 hours to 240 hours after admission. The initial mean serum zinc concentration at less than 24 hours after admission was significantly lower (P<.05) than the concentrations at 97–168 and 169–240 hours post admission. The initial mean serum zinc of 41 ug/dl was also lower than the mean of 87 ug/dl observed in twelve healthy males. By 240 hours after admission 6 of the 8 patients had serum zinc values comparable to the healthy males. Serum zinc concentration was significantly correlated (P <.05) with serum alkaline phosphatase but not with serum total protein, albumin or urea nitrogen. An increase in urinary zinc excretion compared to that observed in the twelve healthy men did not occur until 97–168 hours post admission. An increase in urinary creatinine excretion also occurred at this time period, which suggests that the increased loss of zinc was due to muscle catabolism. The initial decrease in serum zinc below values observed for the healthy males was not accompanied by a decrease in serum albumin or an increase in urinary zinc excretion." @default.
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- W2002080188 date "1985-03-01" @default.
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- W2002080188 title "Serum zinc and urinary zinc excretion of trauma patients" @default.
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- W2002080188 doi "https://doi.org/10.1016/s0271-5317(85)80003-8" @default.
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